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Applications of fluorescent sensor based on 1H-pyrazolo[3,4-b]quinoline in analytical chemistry.

Mac M, Uchacz T, Danel A, Musiolik H - J Fluoresc (2013)

Bottom Line: Relatively high sensitivity but poor selectivity of the amino alcohol that contains indicator towards the two-valued cations was observed.However, upon addition of some amounts of water the selectivity of this sensor has been enhanced (especially towards lead cation).The preliminary results in analytical application of the sensor are discussed.

View Article: PubMed Central - PubMed

Affiliation: Faculty of Chemistry, Jagiellonian University, Ingardena 3, 30-060, Krakow, Poland.

ABSTRACT
Fluorescent dye 2-[(2-Hydroxyethyl)-(1,3-diphenyl-1H-pyrazolo[3,4-b]quinolin-6-ylmethyl)-amino]ethanol (LL1) was examined for its efficiency in the detection of small inorganic cations (lithium, sodium, barium, calcium, magnesium, cadmium, lead and zinc). The dye was synthesized in the laboratory and investigated by means of both, steady-state and time-resolved fluorescence techniques. This compound acts as a fluorescent sensor suitable for detection of small inorganic cations (lithium, sodium, barium, calcium, magnesium, cadmium, lead and zinc) in strongly polar solvent (acetonitrile). An electron transfer from the electro-donative part (receptor) of the molecule to the acceptor part (fluorophore) is thought to be the main mechanism that underlies functionality of the compound as a sensor. This process can be retarded upon complexation of the receptor moiety by inorganic cations. Relatively high sensitivity but poor selectivity of the amino alcohol that contains indicator towards the two-valued cations was observed. However, upon addition of some amounts of water the selectivity of this sensor has been enhanced (especially towards lead cation). The preliminary results in analytical application of the sensor are discussed.

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Dependence of the integrated fluorescence of the mixture of LL1 (4 × 10−5M) and Pb(ClO4)2 (1 × 10−3M) on the volume of the added TBACl (concentration 2 × 10−2M). Initial volume of the mixture of LL1 and Pb(ClO4)2 is 1 ml. Inset: the first derivative of the titration curve with a minimum (equivalence point) c.a. 0.09 ml of TBACl
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Fig5: Dependence of the integrated fluorescence of the mixture of LL1 (4 × 10−5M) and Pb(ClO4)2 (1 × 10−3M) on the volume of the added TBACl (concentration 2 × 10−2M). Initial volume of the mixture of LL1 and Pb(ClO4)2 is 1 ml. Inset: the first derivative of the titration curve with a minimum (equivalence point) c.a. 0.09 ml of TBACl

Mentions: The fluorimetric titration of LL1-Pb2+ complex by tetrabutylammonium chloride (TBACl) was performed in acetonitrile. Addition of TBACl to the solution of Pb(ClO4)2 causes a precipitation of PbCl2 with a residue that is hardly soluble in acetonitrile. Further addition of Cl- anions dissolves the precipitate due to formation of the anion complex Pb(Cl4)2- [18]. The titration process can be monitored by fluorescence techniques in the presence of nonfluorescent LL1 dye (Fig. 5). Both PbCl2 and Pb(Cl4)2- cannot form a fluorescent complex with LL1.Fig. 5


Applications of fluorescent sensor based on 1H-pyrazolo[3,4-b]quinoline in analytical chemistry.

Mac M, Uchacz T, Danel A, Musiolik H - J Fluoresc (2013)

Dependence of the integrated fluorescence of the mixture of LL1 (4 × 10−5M) and Pb(ClO4)2 (1 × 10−3M) on the volume of the added TBACl (concentration 2 × 10−2M). Initial volume of the mixture of LL1 and Pb(ClO4)2 is 1 ml. Inset: the first derivative of the titration curve with a minimum (equivalence point) c.a. 0.09 ml of TBACl
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Related In: Results  -  Collection

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getmorefigures.php?uid=PMC3824276&req=5

Fig5: Dependence of the integrated fluorescence of the mixture of LL1 (4 × 10−5M) and Pb(ClO4)2 (1 × 10−3M) on the volume of the added TBACl (concentration 2 × 10−2M). Initial volume of the mixture of LL1 and Pb(ClO4)2 is 1 ml. Inset: the first derivative of the titration curve with a minimum (equivalence point) c.a. 0.09 ml of TBACl
Mentions: The fluorimetric titration of LL1-Pb2+ complex by tetrabutylammonium chloride (TBACl) was performed in acetonitrile. Addition of TBACl to the solution of Pb(ClO4)2 causes a precipitation of PbCl2 with a residue that is hardly soluble in acetonitrile. Further addition of Cl- anions dissolves the precipitate due to formation of the anion complex Pb(Cl4)2- [18]. The titration process can be monitored by fluorescence techniques in the presence of nonfluorescent LL1 dye (Fig. 5). Both PbCl2 and Pb(Cl4)2- cannot form a fluorescent complex with LL1.Fig. 5

Bottom Line: Relatively high sensitivity but poor selectivity of the amino alcohol that contains indicator towards the two-valued cations was observed.However, upon addition of some amounts of water the selectivity of this sensor has been enhanced (especially towards lead cation).The preliminary results in analytical application of the sensor are discussed.

View Article: PubMed Central - PubMed

Affiliation: Faculty of Chemistry, Jagiellonian University, Ingardena 3, 30-060, Krakow, Poland.

ABSTRACT
Fluorescent dye 2-[(2-Hydroxyethyl)-(1,3-diphenyl-1H-pyrazolo[3,4-b]quinolin-6-ylmethyl)-amino]ethanol (LL1) was examined for its efficiency in the detection of small inorganic cations (lithium, sodium, barium, calcium, magnesium, cadmium, lead and zinc). The dye was synthesized in the laboratory and investigated by means of both, steady-state and time-resolved fluorescence techniques. This compound acts as a fluorescent sensor suitable for detection of small inorganic cations (lithium, sodium, barium, calcium, magnesium, cadmium, lead and zinc) in strongly polar solvent (acetonitrile). An electron transfer from the electro-donative part (receptor) of the molecule to the acceptor part (fluorophore) is thought to be the main mechanism that underlies functionality of the compound as a sensor. This process can be retarded upon complexation of the receptor moiety by inorganic cations. Relatively high sensitivity but poor selectivity of the amino alcohol that contains indicator towards the two-valued cations was observed. However, upon addition of some amounts of water the selectivity of this sensor has been enhanced (especially towards lead cation). The preliminary results in analytical application of the sensor are discussed.

Show MeSH
Related in: MedlinePlus