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Applications of fluorescent sensor based on 1H-pyrazolo[3,4-b]quinoline in analytical chemistry.

Mac M, Uchacz T, Danel A, Musiolik H - J Fluoresc (2013)

Bottom Line: Relatively high sensitivity but poor selectivity of the amino alcohol that contains indicator towards the two-valued cations was observed.However, upon addition of some amounts of water the selectivity of this sensor has been enhanced (especially towards lead cation).The preliminary results in analytical application of the sensor are discussed.

View Article: PubMed Central - PubMed

Affiliation: Faculty of Chemistry, Jagiellonian University, Ingardena 3, 30-060, Krakow, Poland.

ABSTRACT
Fluorescent dye 2-[(2-Hydroxyethyl)-(1,3-diphenyl-1H-pyrazolo[3,4-b]quinolin-6-ylmethyl)-amino]ethanol (LL1) was examined for its efficiency in the detection of small inorganic cations (lithium, sodium, barium, calcium, magnesium, cadmium, lead and zinc). The dye was synthesized in the laboratory and investigated by means of both, steady-state and time-resolved fluorescence techniques. This compound acts as a fluorescent sensor suitable for detection of small inorganic cations (lithium, sodium, barium, calcium, magnesium, cadmium, lead and zinc) in strongly polar solvent (acetonitrile). An electron transfer from the electro-donative part (receptor) of the molecule to the acceptor part (fluorophore) is thought to be the main mechanism that underlies functionality of the compound as a sensor. This process can be retarded upon complexation of the receptor moiety by inorganic cations. Relatively high sensitivity but poor selectivity of the amino alcohol that contains indicator towards the two-valued cations was observed. However, upon addition of some amounts of water the selectivity of this sensor has been enhanced (especially towards lead cation). The preliminary results in analytical application of the sensor are discussed.

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Dependence of the integrated fluorescence of the complex LL1Me2+ on concentration of water in ACN-H2O mixtures
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Fig4: Dependence of the integrated fluorescence of the complex LL1Me2+ on concentration of water in ACN-H2O mixtures

Mentions: The selectivity of the LL1 can be improved by performing fluorimetric measurements in acetonitrile-water mixtures. By adding small amounts of water to the acetonitrile solution of the complex LL1 with magnesium cation can quench fluorescence of the complex almost completely (Fig. 4). The fluorescence of the magnesium complex was immediately quenched in the mixture containing 0.1 molar fraction of water (B), while the complexes with other bivalent cations are almost unaffected and the fluorescence intensity stays the same as in pure acetonitrile (A). However, a systematic increase of water concentration quenches fluorescence of other complexes except of the Pb2+-LL1 complex (C). This is probably the result of different ability of the cations to hydrate.Fig. 4


Applications of fluorescent sensor based on 1H-pyrazolo[3,4-b]quinoline in analytical chemistry.

Mac M, Uchacz T, Danel A, Musiolik H - J Fluoresc (2013)

Dependence of the integrated fluorescence of the complex LL1Me2+ on concentration of water in ACN-H2O mixtures
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3824276&req=5

Fig4: Dependence of the integrated fluorescence of the complex LL1Me2+ on concentration of water in ACN-H2O mixtures
Mentions: The selectivity of the LL1 can be improved by performing fluorimetric measurements in acetonitrile-water mixtures. By adding small amounts of water to the acetonitrile solution of the complex LL1 with magnesium cation can quench fluorescence of the complex almost completely (Fig. 4). The fluorescence of the magnesium complex was immediately quenched in the mixture containing 0.1 molar fraction of water (B), while the complexes with other bivalent cations are almost unaffected and the fluorescence intensity stays the same as in pure acetonitrile (A). However, a systematic increase of water concentration quenches fluorescence of other complexes except of the Pb2+-LL1 complex (C). This is probably the result of different ability of the cations to hydrate.Fig. 4

Bottom Line: Relatively high sensitivity but poor selectivity of the amino alcohol that contains indicator towards the two-valued cations was observed.However, upon addition of some amounts of water the selectivity of this sensor has been enhanced (especially towards lead cation).The preliminary results in analytical application of the sensor are discussed.

View Article: PubMed Central - PubMed

Affiliation: Faculty of Chemistry, Jagiellonian University, Ingardena 3, 30-060, Krakow, Poland.

ABSTRACT
Fluorescent dye 2-[(2-Hydroxyethyl)-(1,3-diphenyl-1H-pyrazolo[3,4-b]quinolin-6-ylmethyl)-amino]ethanol (LL1) was examined for its efficiency in the detection of small inorganic cations (lithium, sodium, barium, calcium, magnesium, cadmium, lead and zinc). The dye was synthesized in the laboratory and investigated by means of both, steady-state and time-resolved fluorescence techniques. This compound acts as a fluorescent sensor suitable for detection of small inorganic cations (lithium, sodium, barium, calcium, magnesium, cadmium, lead and zinc) in strongly polar solvent (acetonitrile). An electron transfer from the electro-donative part (receptor) of the molecule to the acceptor part (fluorophore) is thought to be the main mechanism that underlies functionality of the compound as a sensor. This process can be retarded upon complexation of the receptor moiety by inorganic cations. Relatively high sensitivity but poor selectivity of the amino alcohol that contains indicator towards the two-valued cations was observed. However, upon addition of some amounts of water the selectivity of this sensor has been enhanced (especially towards lead cation). The preliminary results in analytical application of the sensor are discussed.

Show MeSH
Related in: MedlinePlus