Limits...
The 6-minute walk test and other endpoints in Duchenne muscular dystrophy: longitudinal natural history observations over 48 weeks from a multicenter study.

McDonald CM, Henricson EK, Abresch RT, Florence JM, Eagle M, Gappmaier E, Glanzman AM, PTC124-GD-007-DMD Study GroupSpiegel R, Barth J, Elfring G, Reha A, Peltz S - Muscle Nerve (2013)

Bottom Line: Baseline age (≥7 years), 6MWD, and selected TFT performance are strong predictors of decline in ambulation (Δ6MWD) and time to 10% worsening in 6MWD.A baseline 6MWD of <350 meters was associated with greater functional decline, and loss of ambulation was only seen in those with baseline 6MWD <325 meters.Only 1 of 42 (2.3%) subjects able to stand from supine lost ambulation.

View Article: PubMed Central - PubMed

Affiliation: Department of Physical Medicine and Rehabilitation, University of California Davis School of Medicine, Davis, California, 95817, USA.

Show MeSH

Related in: MedlinePlus

Relationship between percent change in 6MWD and percent change in 10-m run/walk test.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3824082&req=5

fig03: Relationship between percent change in 6MWD and percent change in 10-m run/walk test.

Mentions: It is useful to evaluate the relationship between percent change in 10-m run/walk test and percent change in 6MWD to establish links between 6MWD data with longer-term 10-m run/walk data. Figure 3 shows a strong linear relationship between these 2 different types of ambulation measurement (r = 0.89, P < 0.00001).


The 6-minute walk test and other endpoints in Duchenne muscular dystrophy: longitudinal natural history observations over 48 weeks from a multicenter study.

McDonald CM, Henricson EK, Abresch RT, Florence JM, Eagle M, Gappmaier E, Glanzman AM, PTC124-GD-007-DMD Study GroupSpiegel R, Barth J, Elfring G, Reha A, Peltz S - Muscle Nerve (2013)

Relationship between percent change in 6MWD and percent change in 10-m run/walk test.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3824082&req=5

fig03: Relationship between percent change in 6MWD and percent change in 10-m run/walk test.
Mentions: It is useful to evaluate the relationship between percent change in 10-m run/walk test and percent change in 6MWD to establish links between 6MWD data with longer-term 10-m run/walk data. Figure 3 shows a strong linear relationship between these 2 different types of ambulation measurement (r = 0.89, P < 0.00001).

Bottom Line: Baseline age (≥7 years), 6MWD, and selected TFT performance are strong predictors of decline in ambulation (Δ6MWD) and time to 10% worsening in 6MWD.A baseline 6MWD of <350 meters was associated with greater functional decline, and loss of ambulation was only seen in those with baseline 6MWD <325 meters.Only 1 of 42 (2.3%) subjects able to stand from supine lost ambulation.

View Article: PubMed Central - PubMed

Affiliation: Department of Physical Medicine and Rehabilitation, University of California Davis School of Medicine, Davis, California, 95817, USA.

Show MeSH
Related in: MedlinePlus