Structural and ultrastructural evidence for telocytes in prostate stroma.
Bottom Line: They were found primarily in the subepithelial area and also at the periphery of SMC layers.TCs also exhibited moniliform processes, caveolae and nuclei surrounded by small amounts of cytoplasm.Close contacts between TC podomers were evident, particularly in the adjacent epithelial compartment.
Affiliation: Department of Biology, Institute of Biosciences, Humanities and Exact Sciences (IBILCE), Univ. Estadual Paulista - UNESP, São José do Rio Preto, São Paulo, Brazil.Show MeSH
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Mentions: As shown in Figure 1A, for the acini of the gerbil ventral prostate, the glandular epithelial compartment was surrounded by vascularized connective tissue stroma in which smooth muscle bundles surrounded each acinus. The epithelium was simple or pseudostratified and comprised columnar cells. In the stroma, a complex arrangement of cells and ECM components, SMCs were well organized in a densely packed layer surrounding the acinar epithelium. Moreover, collagen and reticular fibres were noted that were interspersed throughout the stroma, primarily along the basal aspect of epithelial structures, but also among SMCs. Immune cells, fibroblasts, blood vessels and nerves were also found in the stromal compartment.
Affiliation: Department of Biology, Institute of Biosciences, Humanities and Exact Sciences (IBILCE), Univ. Estadual Paulista - UNESP, São José do Rio Preto, São Paulo, Brazil.