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Structural and ultrastructural evidence for telocytes in prostate stroma.

Corradi LS, Jesus MM, Fochi RA, Vilamaior PS, Justulin LA, Góes RM, Felisbino SL, Taboga SR - J. Cell. Mol. Med. (2013)

Bottom Line: They were found primarily in the subepithelial area and also at the periphery of SMC layers.TCs also exhibited moniliform processes, caveolae and nuclei surrounded by small amounts of cytoplasm.Close contacts between TC podomers were evident, particularly in the adjacent epithelial compartment.

View Article: PubMed Central - PubMed

Affiliation: Department of Biology, Institute of Biosciences, Humanities and Exact Sciences (IBILCE), Univ. Estadual Paulista - UNESP, São José do Rio Preto, São Paulo, Brazil.

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Related in: MedlinePlus

Prostate haematoxylin and eosin stained sections. (A) General features of the gerbil ventral prostate exhibiting acini (a) and periacinar smooth muscle cells (smc) organized in a densely packed layer, which is surrounded by connective tissue stroma (s). The epithelium (ep) is tall columnar. Blood vessels (v). (B–E) Telocytes (arrows) can be observed adjacent to the epithelial (ep) compartment and at the periphery of the smc layer. The phenotypic characteristics of this novel cell type are shown by the small cellular body with the presence of telopodes (asterisks) that are very thin and extremely long. Fibroblast (f).
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fig01: Prostate haematoxylin and eosin stained sections. (A) General features of the gerbil ventral prostate exhibiting acini (a) and periacinar smooth muscle cells (smc) organized in a densely packed layer, which is surrounded by connective tissue stroma (s). The epithelium (ep) is tall columnar. Blood vessels (v). (B–E) Telocytes (arrows) can be observed adjacent to the epithelial (ep) compartment and at the periphery of the smc layer. The phenotypic characteristics of this novel cell type are shown by the small cellular body with the presence of telopodes (asterisks) that are very thin and extremely long. Fibroblast (f).

Mentions: As shown in Figure 1A, for the acini of the gerbil ventral prostate, the glandular epithelial compartment was surrounded by vascularized connective tissue stroma in which smooth muscle bundles surrounded each acinus. The epithelium was simple or pseudostratified and comprised columnar cells. In the stroma, a complex arrangement of cells and ECM components, SMCs were well organized in a densely packed layer surrounding the acinar epithelium. Moreover, collagen and reticular fibres were noted that were interspersed throughout the stroma, primarily along the basal aspect of epithelial structures, but also among SMCs. Immune cells, fibroblasts, blood vessels and nerves were also found in the stromal compartment.


Structural and ultrastructural evidence for telocytes in prostate stroma.

Corradi LS, Jesus MM, Fochi RA, Vilamaior PS, Justulin LA, Góes RM, Felisbino SL, Taboga SR - J. Cell. Mol. Med. (2013)

Prostate haematoxylin and eosin stained sections. (A) General features of the gerbil ventral prostate exhibiting acini (a) and periacinar smooth muscle cells (smc) organized in a densely packed layer, which is surrounded by connective tissue stroma (s). The epithelium (ep) is tall columnar. Blood vessels (v). (B–E) Telocytes (arrows) can be observed adjacent to the epithelial (ep) compartment and at the periphery of the smc layer. The phenotypic characteristics of this novel cell type are shown by the small cellular body with the presence of telopodes (asterisks) that are very thin and extremely long. Fibroblast (f).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3823021&req=5

fig01: Prostate haematoxylin and eosin stained sections. (A) General features of the gerbil ventral prostate exhibiting acini (a) and periacinar smooth muscle cells (smc) organized in a densely packed layer, which is surrounded by connective tissue stroma (s). The epithelium (ep) is tall columnar. Blood vessels (v). (B–E) Telocytes (arrows) can be observed adjacent to the epithelial (ep) compartment and at the periphery of the smc layer. The phenotypic characteristics of this novel cell type are shown by the small cellular body with the presence of telopodes (asterisks) that are very thin and extremely long. Fibroblast (f).
Mentions: As shown in Figure 1A, for the acini of the gerbil ventral prostate, the glandular epithelial compartment was surrounded by vascularized connective tissue stroma in which smooth muscle bundles surrounded each acinus. The epithelium was simple or pseudostratified and comprised columnar cells. In the stroma, a complex arrangement of cells and ECM components, SMCs were well organized in a densely packed layer surrounding the acinar epithelium. Moreover, collagen and reticular fibres were noted that were interspersed throughout the stroma, primarily along the basal aspect of epithelial structures, but also among SMCs. Immune cells, fibroblasts, blood vessels and nerves were also found in the stromal compartment.

Bottom Line: They were found primarily in the subepithelial area and also at the periphery of SMC layers.TCs also exhibited moniliform processes, caveolae and nuclei surrounded by small amounts of cytoplasm.Close contacts between TC podomers were evident, particularly in the adjacent epithelial compartment.

View Article: PubMed Central - PubMed

Affiliation: Department of Biology, Institute of Biosciences, Humanities and Exact Sciences (IBILCE), Univ. Estadual Paulista - UNESP, São José do Rio Preto, São Paulo, Brazil.

Show MeSH
Related in: MedlinePlus