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Increased hair selenium concentration in hyperlipidemic patients.

Fülöp P, Seres I, Jenei Z, Juhász I, Paragh G - J. Cell. Mol. Med. (2013)

Bottom Line: Therefore, we analysed selenium concentrations by X-ray fluorescence in the hair of 81 statin-naïve patients with newly diagnosed Fredrickson-type IIa and IIb hyperlipoproteinemia and compared their data with 43 healthy volunteers.Hair selenium levels were found to be significantly higher in hyperlipidemic patients compared with volunteers with normal lipid levels.Our results suggest that high hair selenium status might be associated with adverse blood lipid profile together with an increased number of traditional risk factors in a selenium-deplete population.

View Article: PubMed Central - PubMed

Affiliation: Institute of Internal Medicine, University of Debrecen Medical and Health Science Center, Debrecen, Hungary.

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Number of risk factors in hyperlipidemic patients with below and above the median of log hair selenium (P = 0.0025).
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fig01: Number of risk factors in hyperlipidemic patients with below and above the median of log hair selenium (P = 0.0025).

Mentions: Assessing the prevalence of all risk factors, we found that hyperlipidemic patients in the high-selenium group had significantly more traditional risk factors of atherosclerosis (P = 0.0025) compared with those with low hair selenium concentration (Fig. 1). Our results indicate that 50% of the patients with low hair selenium levels possessed one or more risk factors other than hyperlipidemia, whereas this ratio was found to be 75% in individuals with hair selenium levels exceeding the median.


Increased hair selenium concentration in hyperlipidemic patients.

Fülöp P, Seres I, Jenei Z, Juhász I, Paragh G - J. Cell. Mol. Med. (2013)

Number of risk factors in hyperlipidemic patients with below and above the median of log hair selenium (P = 0.0025).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3823016&req=5

fig01: Number of risk factors in hyperlipidemic patients with below and above the median of log hair selenium (P = 0.0025).
Mentions: Assessing the prevalence of all risk factors, we found that hyperlipidemic patients in the high-selenium group had significantly more traditional risk factors of atherosclerosis (P = 0.0025) compared with those with low hair selenium concentration (Fig. 1). Our results indicate that 50% of the patients with low hair selenium levels possessed one or more risk factors other than hyperlipidemia, whereas this ratio was found to be 75% in individuals with hair selenium levels exceeding the median.

Bottom Line: Therefore, we analysed selenium concentrations by X-ray fluorescence in the hair of 81 statin-naïve patients with newly diagnosed Fredrickson-type IIa and IIb hyperlipoproteinemia and compared their data with 43 healthy volunteers.Hair selenium levels were found to be significantly higher in hyperlipidemic patients compared with volunteers with normal lipid levels.Our results suggest that high hair selenium status might be associated with adverse blood lipid profile together with an increased number of traditional risk factors in a selenium-deplete population.

View Article: PubMed Central - PubMed

Affiliation: Institute of Internal Medicine, University of Debrecen Medical and Health Science Center, Debrecen, Hungary.

Show MeSH
Related in: MedlinePlus