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Measles outbreak response immunization is context-specific: insight from the recent experience of Médecins Sans Frontières.

Minetti A, Bopp C, Fermon F, François G, Grais RF, Grout L, Hurtado N, Luquero FJ, Porten K, Sury L, Terzian M - PLoS Med. (2013)

Bottom Line: Andrea Minetti and colleagues compare measles outbreak responses from the Democratic Republic of the Congo and Malawi and argue that outbreak response strategies should be tailored to local measles epidemiology.Please see later in the article for the Editors' Summary.

View Article: PubMed Central - PubMed

Affiliation: Epicentre, Paris, France.

ABSTRACT
Andrea Minetti and colleagues compare measles outbreak responses from the Democratic Republic of the Congo and Malawi and argue that outbreak response strategies should be tailored to local measles epidemiology. Please see later in the article for the Editors' Summary.

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Related in: MedlinePlus

Age distribution of measles cases in Katanga Province (Democratic Republic of the Congo), 2010–2011, and in Malawi, 2010, as represented by attack rates, with incidence risk ratio by age.The incidence risk ratio (irr) is the age-specific AR in Katanga divided by the age-specific AR in Malawi.
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pmed-1001544-g001: Age distribution of measles cases in Katanga Province (Democratic Republic of the Congo), 2010–2011, and in Malawi, 2010, as represented by attack rates, with incidence risk ratio by age.The incidence risk ratio (irr) is the age-specific AR in Katanga divided by the age-specific AR in Malawi.

Mentions: The epidemiological profiles of these two epidemics are distinguishable by the age distribution of cases. In Katanga, the median age of cases was 2 years (interquartile range: 1–4), with 80% of reported cases in children <5 years old and only 6% in individuals ≥10 years old. In Malawi, the median age of cases was 7 years (interquartile range: 1–16), with 41% of reported cases in children <5 years old and 28% in individuals ≥15 years old (Table 1). In both countries, almost a fifth of cases were in children <1 years old—including children in the Expanded Programme on Immunization target group and younger—with ARs around 5%. In Katanga, young children (12–59 months old) were also highly affected, with AR sharply decreasing in older children. In Malawi, the AR was lower for young children than for children of the same age in Katanga, but much higher for age groups >;5 years old, as shown by the incidence risk ratio (Figure 1).


Measles outbreak response immunization is context-specific: insight from the recent experience of Médecins Sans Frontières.

Minetti A, Bopp C, Fermon F, François G, Grais RF, Grout L, Hurtado N, Luquero FJ, Porten K, Sury L, Terzian M - PLoS Med. (2013)

Age distribution of measles cases in Katanga Province (Democratic Republic of the Congo), 2010–2011, and in Malawi, 2010, as represented by attack rates, with incidence risk ratio by age.The incidence risk ratio (irr) is the age-specific AR in Katanga divided by the age-specific AR in Malawi.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3818158&req=5

pmed-1001544-g001: Age distribution of measles cases in Katanga Province (Democratic Republic of the Congo), 2010–2011, and in Malawi, 2010, as represented by attack rates, with incidence risk ratio by age.The incidence risk ratio (irr) is the age-specific AR in Katanga divided by the age-specific AR in Malawi.
Mentions: The epidemiological profiles of these two epidemics are distinguishable by the age distribution of cases. In Katanga, the median age of cases was 2 years (interquartile range: 1–4), with 80% of reported cases in children <5 years old and only 6% in individuals ≥10 years old. In Malawi, the median age of cases was 7 years (interquartile range: 1–16), with 41% of reported cases in children <5 years old and 28% in individuals ≥15 years old (Table 1). In both countries, almost a fifth of cases were in children <1 years old—including children in the Expanded Programme on Immunization target group and younger—with ARs around 5%. In Katanga, young children (12–59 months old) were also highly affected, with AR sharply decreasing in older children. In Malawi, the AR was lower for young children than for children of the same age in Katanga, but much higher for age groups >;5 years old, as shown by the incidence risk ratio (Figure 1).

Bottom Line: Andrea Minetti and colleagues compare measles outbreak responses from the Democratic Republic of the Congo and Malawi and argue that outbreak response strategies should be tailored to local measles epidemiology.Please see later in the article for the Editors' Summary.

View Article: PubMed Central - PubMed

Affiliation: Epicentre, Paris, France.

ABSTRACT
Andrea Minetti and colleagues compare measles outbreak responses from the Democratic Republic of the Congo and Malawi and argue that outbreak response strategies should be tailored to local measles epidemiology. Please see later in the article for the Editors' Summary.

Show MeSH
Related in: MedlinePlus