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Glucose metabolic flux distribution of Lactobacillus amylophilus during lactic acid production using kitchen waste saccharified solution.

Liu J, Wang Q, Zou H, Liu Y, Wang J, Gan K, Xiang J - Microb Biotechnol (2013)

Bottom Line: The flux to the EMP was also effectively increased.However, the addition of Zn(2+) showed an opposite effect, decreasing the lactic acid production.In conclusion it is feasible and effective means using GC-MS, isotope experiment and MATLAB software to integrate research the metabolic flux distribution of lactic acid bacteria, and the results provide the theoretical foundation for similar metabolic flux distribution.

View Article: PubMed Central - PubMed

Affiliation: School of Civil and Environmental Engineering, University of Science and Technology Beijing, 30 Xueyuan Road, Haidian District, Beijing, 100083, China; Key Laboratory of Educational Ministry for High Efficient Mining and Safety in Metal Mine, University of Science and Technology Beijing, Beijing, 100083, China.

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Key enzymes related to lactic acid synthesis pathway.
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fig03: Key enzymes related to lactic acid synthesis pathway.

Mentions: Figure 3 shows the key enzymes in lactic acid biosynthesis. The change in the activity of these enzymes directly affects lactic acid formation. Promoting LDH activity and inhibiting the activity of PDC, PC and PDHc are effective strategies for optimizing the metabolic pathway to increase lactic production during fermentation.


Glucose metabolic flux distribution of Lactobacillus amylophilus during lactic acid production using kitchen waste saccharified solution.

Liu J, Wang Q, Zou H, Liu Y, Wang J, Gan K, Xiang J - Microb Biotechnol (2013)

Key enzymes related to lactic acid synthesis pathway.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3815935&req=5

fig03: Key enzymes related to lactic acid synthesis pathway.
Mentions: Figure 3 shows the key enzymes in lactic acid biosynthesis. The change in the activity of these enzymes directly affects lactic acid formation. Promoting LDH activity and inhibiting the activity of PDC, PC and PDHc are effective strategies for optimizing the metabolic pathway to increase lactic production during fermentation.

Bottom Line: The flux to the EMP was also effectively increased.However, the addition of Zn(2+) showed an opposite effect, decreasing the lactic acid production.In conclusion it is feasible and effective means using GC-MS, isotope experiment and MATLAB software to integrate research the metabolic flux distribution of lactic acid bacteria, and the results provide the theoretical foundation for similar metabolic flux distribution.

View Article: PubMed Central - PubMed

Affiliation: School of Civil and Environmental Engineering, University of Science and Technology Beijing, 30 Xueyuan Road, Haidian District, Beijing, 100083, China; Key Laboratory of Educational Ministry for High Efficient Mining and Safety in Metal Mine, University of Science and Technology Beijing, Beijing, 100083, China.

Show MeSH
Related in: MedlinePlus