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Xenomic networks variability and adaptation traits in wood decaying fungi.

Morel M, Meux E, Mathieu Y, Thuillier A, Chibani K, Harvengt L, Jacquot JP, Gelhaye E - Microb Biotechnol (2013)

Bottom Line: Taking advantage of the recent release of numerous genomes of basidiomycetes, we show here that these multigenic families are extended and functionally related in wood-decaying fungi.Furthermore, we postulate that these rapidly evolving multigenic families could reflect the adaptation of these fungi to the diversity of their substrate and provide keys to understand their ecology.This is of particular importance for white biotechnology, this xenome being a putative target for improving degradation properties of these fungi in biomass valorization purposes.

View Article: PubMed Central - PubMed

Affiliation: Université de Lorraine, IAM, UMR 1136, IFR 110 EFABA, Vandoeuvre-lès-Nancy, F-54506, France. mmorel@scbiol.uhp-nancy.fr

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The fungal detoxification system defined as ‘xenome’.
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fig01: The fungal detoxification system defined as ‘xenome’.

Mentions: Facing this large diversity of nutriments and potential toxic component sources, fungi, which mainly control wood decomposition in forest ecosystems, have also concomitantly evolved modified detoxification pathways, defining the xenome (Edwards et al., 2005). As in other eukaryotic organisms, the detoxification pathways dealing with recalcitrant/toxic compounds can be divided into three different steps in fungi, the first one corresponding to an activation of the molecule often through an oxidation stage, the second one to a conjugation stage, and the third one either to transport or to storage (Fig. 1). In this article, we will focus mainly on the oxidation and conjugation steps found in wood-decaying fungi through the determination of their xenomic gene content in relation to their environment.


Xenomic networks variability and adaptation traits in wood decaying fungi.

Morel M, Meux E, Mathieu Y, Thuillier A, Chibani K, Harvengt L, Jacquot JP, Gelhaye E - Microb Biotechnol (2013)

The fungal detoxification system defined as ‘xenome’.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3815920&req=5

fig01: The fungal detoxification system defined as ‘xenome’.
Mentions: Facing this large diversity of nutriments and potential toxic component sources, fungi, which mainly control wood decomposition in forest ecosystems, have also concomitantly evolved modified detoxification pathways, defining the xenome (Edwards et al., 2005). As in other eukaryotic organisms, the detoxification pathways dealing with recalcitrant/toxic compounds can be divided into three different steps in fungi, the first one corresponding to an activation of the molecule often through an oxidation stage, the second one to a conjugation stage, and the third one either to transport or to storage (Fig. 1). In this article, we will focus mainly on the oxidation and conjugation steps found in wood-decaying fungi through the determination of their xenomic gene content in relation to their environment.

Bottom Line: Taking advantage of the recent release of numerous genomes of basidiomycetes, we show here that these multigenic families are extended and functionally related in wood-decaying fungi.Furthermore, we postulate that these rapidly evolving multigenic families could reflect the adaptation of these fungi to the diversity of their substrate and provide keys to understand their ecology.This is of particular importance for white biotechnology, this xenome being a putative target for improving degradation properties of these fungi in biomass valorization purposes.

View Article: PubMed Central - PubMed

Affiliation: Université de Lorraine, IAM, UMR 1136, IFR 110 EFABA, Vandoeuvre-lès-Nancy, F-54506, France. mmorel@scbiol.uhp-nancy.fr

Show MeSH
Related in: MedlinePlus