Community structure and antibiotic production of Streptomyces nodosus bioreactors cultured in liquid environments.
Bottom Line: When cell proliferation was encouraged, substrate hyphae were found inside the alginate matrix and within multicellular projections on the surface of the capsule.These organisms sporulated with reduced antibiotic production compared with free-dwelling cultures.The commitment to sporulate was independent of a surface but dependent on community size and nutritional status.
Affiliation: University of Western Sydney, School of Natural Sciences, Parramatta Campus, Locked Bag 1797, Penrith South DC 1797 NSW, Australia.Show MeSH
Related in: MedlinePlus
Mentions: Capsules were cultured in 48 h conditioned media for up to 30 days. Biomass increased in the capsules up to 48 h (Fig. 3a) with the extent of growth comparable to that observed in capsules exposed to non‐conditioned medium (Fig. 1b). Morphologically, the hyphae were indistinguishable between the two samples. On assessment of viability, 54% (n = 5) of hyphae were non‐viable when cultured in the conditioned medium compared with 24% (n = 5) for those in capsules exposed to YMG.
Affiliation: University of Western Sydney, School of Natural Sciences, Parramatta Campus, Locked Bag 1797, Penrith South DC 1797 NSW, Australia.