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Association of self-reported race with AIDS death in continuous HAART users in a cohort of HIV-infected women in the United States.

Murphy K, Hoover DR, Shi Q, Cohen M, Gandhi M, Golub ET, Gustafson DR, Pearce CL, Young M, Anastos K - AIDS (2013)

Bottom Line: Cumulative AIDS death incidence at 10 years was 17.3 and 8.3% for black and white women, respectively.Other significant independent pre-HAART predictors of AIDS death included peak viral load (aHR 1.70 per log₁₀, 95% CI 1.34, 2.16; P < 0.001), nadir CD4⁺ cell count (aHR 0.65 per 100 cells/μl, 95% CI 0.56, 0.76; P < 0.001), depressive symptoms by Center for Epidemiology Studies Depression score at least 16 (aHR 2.10, 95% CI 1.51, 2.92; P < 0.001), hepatitis C virus infection (aHR 1.57, 95% CI 1.02, 2.40; P = 0.04), and HIV acquisition via transfusion (aHR 2.33, 95% CI 1.21, 4.49; P = 0.01).In continuous HAART-using women, black women more rapidly died from AIDS or experienced incident ADI than their white counterparts after adjusting for confounders.

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Affiliation: aAlbert Einstein College of Medicine/Montefiore Medical Center, Bronx, New York bRutgers University, Piscataway, New Jersey cSchool of Health Sciences and Practice/New York Medical College, Valhalla, New York dCook County Health and Hospitals System eRush University, Chicago, Illinois fUniversity of California San Francisco, San Francisco, California gJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland hState University of New York/Downstate Medical Center, Brooklyn, New York, USA iUniversity of Gothenburg, Gothenburg, Sweden jUniversity of Southern California, Los Angeles, California kGeorgetown University, Washington, District of Columbia, USA.

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Cumulative incidence of non-AIDS death over time.
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Figure 2: Cumulative incidence of non-AIDS death over time.

Mentions: Figures 1 and 2 show cumulative incidence of AIDS and non-AIDS death, respectively, stratified by race. Ten years after HAART initiation, black women had the highest cumulative incidence of AIDS death, 17.3 vs. 8.3% for whites and 14.2% for others (Fig. 1), whereas cumulative incidence of non-AIDS death was similar in blacks and whites (13.1 and 12.3%, respectively) and lower (7.7%) in women reporting their race as other (Fig. 2).


Association of self-reported race with AIDS death in continuous HAART users in a cohort of HIV-infected women in the United States.

Murphy K, Hoover DR, Shi Q, Cohen M, Gandhi M, Golub ET, Gustafson DR, Pearce CL, Young M, Anastos K - AIDS (2013)

Cumulative incidence of non-AIDS death over time.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3815041&req=5

Figure 2: Cumulative incidence of non-AIDS death over time.
Mentions: Figures 1 and 2 show cumulative incidence of AIDS and non-AIDS death, respectively, stratified by race. Ten years after HAART initiation, black women had the highest cumulative incidence of AIDS death, 17.3 vs. 8.3% for whites and 14.2% for others (Fig. 1), whereas cumulative incidence of non-AIDS death was similar in blacks and whites (13.1 and 12.3%, respectively) and lower (7.7%) in women reporting their race as other (Fig. 2).

Bottom Line: Cumulative AIDS death incidence at 10 years was 17.3 and 8.3% for black and white women, respectively.Other significant independent pre-HAART predictors of AIDS death included peak viral load (aHR 1.70 per log₁₀, 95% CI 1.34, 2.16; P < 0.001), nadir CD4⁺ cell count (aHR 0.65 per 100 cells/μl, 95% CI 0.56, 0.76; P < 0.001), depressive symptoms by Center for Epidemiology Studies Depression score at least 16 (aHR 2.10, 95% CI 1.51, 2.92; P < 0.001), hepatitis C virus infection (aHR 1.57, 95% CI 1.02, 2.40; P = 0.04), and HIV acquisition via transfusion (aHR 2.33, 95% CI 1.21, 4.49; P = 0.01).In continuous HAART-using women, black women more rapidly died from AIDS or experienced incident ADI than their white counterparts after adjusting for confounders.

View Article: PubMed Central - PubMed

Affiliation: aAlbert Einstein College of Medicine/Montefiore Medical Center, Bronx, New York bRutgers University, Piscataway, New Jersey cSchool of Health Sciences and Practice/New York Medical College, Valhalla, New York dCook County Health and Hospitals System eRush University, Chicago, Illinois fUniversity of California San Francisco, San Francisco, California gJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland hState University of New York/Downstate Medical Center, Brooklyn, New York, USA iUniversity of Gothenburg, Gothenburg, Sweden jUniversity of Southern California, Los Angeles, California kGeorgetown University, Washington, District of Columbia, USA.

Show MeSH
Related in: MedlinePlus