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Ankylosis of the hips and knees due to sickle cell disease.

Al Elayan SS, Al Hamdan A - F1000Res (2012)

Bottom Line: The patient's hemoglobin S decreased to levels below 30% by exchange transfusion.Bilateral total hip replacement, as well as unilateral total knee replacement, was carried out to improve his level of function.These complications were successfully managed and the patient was able to move and transfer using a wheel chair.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedics, Prince Sultan Military Medical City, Riyadh, 11612, Saudi Arabia.

ABSTRACT
This is a case report of a 29-year-old Saudi male with sickle cell disease (SCD) with severe stiffness of his joints, mainly both knees and hips, secondary to complications of SCD. He was severely crippled: unable to sit, stand or walk, and was bedridden for 8 years when he was presented to us. Radiographs showed fusion of both knees and hips. There was no evidence of active osteomyelitis by Gallium scan. The patient's hemoglobin S decreased to levels below 30% by exchange transfusion. Bilateral total hip replacement, as well as unilateral total knee replacement, was carried out to improve his level of function. There is only one reported case of such severe and multiple joint complications in a single patient suffering from SCD. The increased life expectancy that medical advances have offered to the sickle-cell patients has led to the appearance of sickle-cell-related complications, which were previously only seen rarely. These complications were successfully managed and the patient was able to move and transfer using a wheel chair.

No MeSH data available.


Related in: MedlinePlus

AP left & right knee x-ray shows erosion and ankylosis.
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f2: AP left & right knee x-ray shows erosion and ankylosis.

Mentions: Serial radiological studies were done. Radiological investigations demonstrated severe avascular necrosis and ankylosis of the hip (Figure 1) and severe erosion of the articular surfaces of the knees as well as ankylosis (Figure 2). Computed tomography (CT) scan of the hips and knees showed similar findings as that of the X-rays. Shoulders and spine X-ray were done for further assessment. Gallium bone scan demonstrated no evidence of active osteomyelitis. Our patient had a proper preoperative evaluation and blood transfusion to prevent adverse outcomes and sickle cell complications postoperatively5. We took him to surgery for bilateral cementless total hip replacement (THR) in one session.


Ankylosis of the hips and knees due to sickle cell disease.

Al Elayan SS, Al Hamdan A - F1000Res (2012)

AP left & right knee x-ray shows erosion and ankylosis.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3814913&req=5

f2: AP left & right knee x-ray shows erosion and ankylosis.
Mentions: Serial radiological studies were done. Radiological investigations demonstrated severe avascular necrosis and ankylosis of the hip (Figure 1) and severe erosion of the articular surfaces of the knees as well as ankylosis (Figure 2). Computed tomography (CT) scan of the hips and knees showed similar findings as that of the X-rays. Shoulders and spine X-ray were done for further assessment. Gallium bone scan demonstrated no evidence of active osteomyelitis. Our patient had a proper preoperative evaluation and blood transfusion to prevent adverse outcomes and sickle cell complications postoperatively5. We took him to surgery for bilateral cementless total hip replacement (THR) in one session.

Bottom Line: The patient's hemoglobin S decreased to levels below 30% by exchange transfusion.Bilateral total hip replacement, as well as unilateral total knee replacement, was carried out to improve his level of function.These complications were successfully managed and the patient was able to move and transfer using a wheel chair.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedics, Prince Sultan Military Medical City, Riyadh, 11612, Saudi Arabia.

ABSTRACT
This is a case report of a 29-year-old Saudi male with sickle cell disease (SCD) with severe stiffness of his joints, mainly both knees and hips, secondary to complications of SCD. He was severely crippled: unable to sit, stand or walk, and was bedridden for 8 years when he was presented to us. Radiographs showed fusion of both knees and hips. There was no evidence of active osteomyelitis by Gallium scan. The patient's hemoglobin S decreased to levels below 30% by exchange transfusion. Bilateral total hip replacement, as well as unilateral total knee replacement, was carried out to improve his level of function. There is only one reported case of such severe and multiple joint complications in a single patient suffering from SCD. The increased life expectancy that medical advances have offered to the sickle-cell patients has led to the appearance of sickle-cell-related complications, which were previously only seen rarely. These complications were successfully managed and the patient was able to move and transfer using a wheel chair.

No MeSH data available.


Related in: MedlinePlus