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Evaluation of brief screening tools for neurocognitive impairment in HIV/AIDS: a systematic review of the literature.

Zipursky AR, Gogolishvili D, Rueda S, Brunetta J, Carvalhal A, McCombe JA, Gill MJ, Rachlis A, Rosenes R, Arbess G, Marcotte T, Rourke SB - AIDS (2013)

Bottom Line: Fifty-one studies met inclusion criteria; we focused on 31 studies that compared brief screening tools with reference tests.There were significant methodological shortcomings noted in most studies.Further investigation, with improved methodology, is required to understand the utility of newer screening tools for HAND; further tools may need to be developed for milder HAND conditions.

View Article: PubMed Central - PubMed

Affiliation: aOntario HIV Treatment Network bUniversity of Toronto cMaple Leaf Clinic, Toronto, Ontario dSt. Michael's Hospital, Toronto, Ontario eSouthern Alberta HIV Clinic and University of Alberta, Edmonton, Alberta fSunnybrook Hospital, Toronto, Ontario, Canada gUniversity of California, San Diego, La Jolla, California, USA.

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Related in: MedlinePlus

Forest plots.
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Figure 2: Forest plots.

Mentions: The Forest Plot of the meta-analysis of the HDS (Fig. 2a) shows a large range in the sensitivities for the HDS across studies; four studies [19,34,38,42] reported poor sensitivity (i.e. ≤0.55) and three studies [6,40,44] reported good sensitivity (i.e. >0.80). Overall, the pooled sensitivity of these studies (i.e. 0.48) would suggest that the HDS (without any corrections for demographics) is not useful for detecting a range of HAND conditions.


Evaluation of brief screening tools for neurocognitive impairment in HIV/AIDS: a systematic review of the literature.

Zipursky AR, Gogolishvili D, Rueda S, Brunetta J, Carvalhal A, McCombe JA, Gill MJ, Rachlis A, Rosenes R, Arbess G, Marcotte T, Rourke SB - AIDS (2013)

Forest plots.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3814629&req=5

Figure 2: Forest plots.
Mentions: The Forest Plot of the meta-analysis of the HDS (Fig. 2a) shows a large range in the sensitivities for the HDS across studies; four studies [19,34,38,42] reported poor sensitivity (i.e. ≤0.55) and three studies [6,40,44] reported good sensitivity (i.e. >0.80). Overall, the pooled sensitivity of these studies (i.e. 0.48) would suggest that the HDS (without any corrections for demographics) is not useful for detecting a range of HAND conditions.

Bottom Line: Fifty-one studies met inclusion criteria; we focused on 31 studies that compared brief screening tools with reference tests.There were significant methodological shortcomings noted in most studies.Further investigation, with improved methodology, is required to understand the utility of newer screening tools for HAND; further tools may need to be developed for milder HAND conditions.

View Article: PubMed Central - PubMed

Affiliation: aOntario HIV Treatment Network bUniversity of Toronto cMaple Leaf Clinic, Toronto, Ontario dSt. Michael's Hospital, Toronto, Ontario eSouthern Alberta HIV Clinic and University of Alberta, Edmonton, Alberta fSunnybrook Hospital, Toronto, Ontario, Canada gUniversity of California, San Diego, La Jolla, California, USA.

Show MeSH
Related in: MedlinePlus