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Pubertal gynecomastia coincides with peak height velocity.

Limony Y, Friger M, Hochberg Z - J Clin Res Pediatr Endocrinol (2013)

Bottom Line: In this study, we investigated the relationship between the ages at which PG and peak height velocity occur in pubertal boys.This was a prospective study that was designed to detect PG within three months of its emergence.The coincidence of age of peak height velocity and PG suggests a causal relationship between the two events and a role of insulin-like growth factor-1.

View Article: PubMed Central - PubMed

Affiliation: Migdaley-Hakenyon, P.O. Box 616, Beer Sheva 84600, Israel. limony@zahav.net.il.

ABSTRACT

Objective: Pubertal gynecomastia (PG) occurs in up to 65% of adolescent boys. In this study, we investigated the relationship between the ages at which PG and peak height velocity occur in pubertal boys.

Methods: This was a prospective study that was designed to detect PG within three months of its emergence. We examined one hundred and six boys who were followed for short stature and/or delayed puberty at three month intervals, and gynecomastia was observed in 43 of these boys (40.5%).

Results: PG occurred in the 43 boys within a year of their peak height velocity, and most of these boys were at Tanner stage 3 for pubic hair and had testicular volumes between 8-10 mL.

Conclusion: It is recommended that evaluation of height growth be included in the diagnostic approach to PG in boys with short stature and/or delayed puberty. The coincidence of age of peak height velocity and PG suggests a causal relationship between the two events and a role of insulin-like growth factor-1.

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Related in: MedlinePlus

Distribution of the boys according to their bone age when gynecomastia was first observed
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f3: Distribution of the boys according to their bone age when gynecomastia was first observed

Mentions: When gynecomastia was first observed in the 43 boys, the bone age of 28 boys was 12.8±0.9 years (mean±SD) (Figure 3). Thirty of the 43 boys were at Tanner stage 3 for pubic hair (Figure 4), and testicular volume was between 8.0 and 10 mL when gynecomastia was first observed.


Pubertal gynecomastia coincides with peak height velocity.

Limony Y, Friger M, Hochberg Z - J Clin Res Pediatr Endocrinol (2013)

Distribution of the boys according to their bone age when gynecomastia was first observed
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3814527&req=5

f3: Distribution of the boys according to their bone age when gynecomastia was first observed
Mentions: When gynecomastia was first observed in the 43 boys, the bone age of 28 boys was 12.8±0.9 years (mean±SD) (Figure 3). Thirty of the 43 boys were at Tanner stage 3 for pubic hair (Figure 4), and testicular volume was between 8.0 and 10 mL when gynecomastia was first observed.

Bottom Line: In this study, we investigated the relationship between the ages at which PG and peak height velocity occur in pubertal boys.This was a prospective study that was designed to detect PG within three months of its emergence.The coincidence of age of peak height velocity and PG suggests a causal relationship between the two events and a role of insulin-like growth factor-1.

View Article: PubMed Central - PubMed

Affiliation: Migdaley-Hakenyon, P.O. Box 616, Beer Sheva 84600, Israel. limony@zahav.net.il.

ABSTRACT

Objective: Pubertal gynecomastia (PG) occurs in up to 65% of adolescent boys. In this study, we investigated the relationship between the ages at which PG and peak height velocity occur in pubertal boys.

Methods: This was a prospective study that was designed to detect PG within three months of its emergence. We examined one hundred and six boys who were followed for short stature and/or delayed puberty at three month intervals, and gynecomastia was observed in 43 of these boys (40.5%).

Results: PG occurred in the 43 boys within a year of their peak height velocity, and most of these boys were at Tanner stage 3 for pubic hair and had testicular volumes between 8-10 mL.

Conclusion: It is recommended that evaluation of height growth be included in the diagnostic approach to PG in boys with short stature and/or delayed puberty. The coincidence of age of peak height velocity and PG suggests a causal relationship between the two events and a role of insulin-like growth factor-1.

Show MeSH
Related in: MedlinePlus