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Pubertal gynecomastia coincides with peak height velocity.

Limony Y, Friger M, Hochberg Z - J Clin Res Pediatr Endocrinol (2013)

Bottom Line: In this study, we investigated the relationship between the ages at which PG and peak height velocity occur in pubertal boys.This was a prospective study that was designed to detect PG within three months of its emergence.The coincidence of age of peak height velocity and PG suggests a causal relationship between the two events and a role of insulin-like growth factor-1.

View Article: PubMed Central - PubMed

Affiliation: Migdaley-Hakenyon, P.O. Box 616, Beer Sheva 84600, Israel. limony@zahav.net.il.

ABSTRACT

Objective: Pubertal gynecomastia (PG) occurs in up to 65% of adolescent boys. In this study, we investigated the relationship between the ages at which PG and peak height velocity occur in pubertal boys.

Methods: This was a prospective study that was designed to detect PG within three months of its emergence. We examined one hundred and six boys who were followed for short stature and/or delayed puberty at three month intervals, and gynecomastia was observed in 43 of these boys (40.5%).

Results: PG occurred in the 43 boys within a year of their peak height velocity, and most of these boys were at Tanner stage 3 for pubic hair and had testicular volumes between 8-10 mL.

Conclusion: It is recommended that evaluation of height growth be included in the diagnostic approach to PG in boys with short stature and/or delayed puberty. The coincidence of age of peak height velocity and PG suggests a causal relationship between the two events and a role of insulin-like growth factor-1.

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Related in: MedlinePlus

Scatter plot showing a high correlation (r=0.847) between age at which gynecomastia was first observed and age at peak height velocity (PHV)
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f2: Scatter plot showing a high correlation (r=0.847) between age at which gynecomastia was first observed and age at peak height velocity (PHV)

Mentions: Gynecomastia was detected when the boys in the study group were 14.4±0.9 years [mean±standard deviation (SD)] old. Their mean age at PHV was 14.7±1.0 years. Forty-two of the 43 boys (98%) developed gynecomastia within a year of their PHV. Figure 1 shows the distribution of the age difference between PHV and gynecomastia. Age of PHV strongly correlated with the age at which gynecomastia was first observed (r=0.847, p<0.0001, Figure 2).


Pubertal gynecomastia coincides with peak height velocity.

Limony Y, Friger M, Hochberg Z - J Clin Res Pediatr Endocrinol (2013)

Scatter plot showing a high correlation (r=0.847) between age at which gynecomastia was first observed and age at peak height velocity (PHV)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3814527&req=5

f2: Scatter plot showing a high correlation (r=0.847) between age at which gynecomastia was first observed and age at peak height velocity (PHV)
Mentions: Gynecomastia was detected when the boys in the study group were 14.4±0.9 years [mean±standard deviation (SD)] old. Their mean age at PHV was 14.7±1.0 years. Forty-two of the 43 boys (98%) developed gynecomastia within a year of their PHV. Figure 1 shows the distribution of the age difference between PHV and gynecomastia. Age of PHV strongly correlated with the age at which gynecomastia was first observed (r=0.847, p<0.0001, Figure 2).

Bottom Line: In this study, we investigated the relationship between the ages at which PG and peak height velocity occur in pubertal boys.This was a prospective study that was designed to detect PG within three months of its emergence.The coincidence of age of peak height velocity and PG suggests a causal relationship between the two events and a role of insulin-like growth factor-1.

View Article: PubMed Central - PubMed

Affiliation: Migdaley-Hakenyon, P.O. Box 616, Beer Sheva 84600, Israel. limony@zahav.net.il.

ABSTRACT

Objective: Pubertal gynecomastia (PG) occurs in up to 65% of adolescent boys. In this study, we investigated the relationship between the ages at which PG and peak height velocity occur in pubertal boys.

Methods: This was a prospective study that was designed to detect PG within three months of its emergence. We examined one hundred and six boys who were followed for short stature and/or delayed puberty at three month intervals, and gynecomastia was observed in 43 of these boys (40.5%).

Results: PG occurred in the 43 boys within a year of their peak height velocity, and most of these boys were at Tanner stage 3 for pubic hair and had testicular volumes between 8-10 mL.

Conclusion: It is recommended that evaluation of height growth be included in the diagnostic approach to PG in boys with short stature and/or delayed puberty. The coincidence of age of peak height velocity and PG suggests a causal relationship between the two events and a role of insulin-like growth factor-1.

Show MeSH
Related in: MedlinePlus