Synthesis of activated pyrimidine ribonucleotides 1 and

Limits...

Detection of potential TNA and RNA nucleoside precursors in a prebiotic mixture by pure shift diffusion-ordered NMR spectroscopy. Islam S, Aguilar JA, Powner MW, Nilsson M, Morris GA, Sutherland JD - Chemistry (2013) Bottom Line: One potential avenue is the combination of pure shift methodology, in which NMR spectra are measured with greatly improved resolution by suppressing multiplet structure, with diffusion-ordered spectroscopy, in which NMR signals from different species are distinguished through their different rates of diffusion.Such a combination has the added advantage of working with intact mixtures, allowing analyses to be carried out without perturbing mixtures in which chemical entities are part of a network of reactions in equilibrium.The direct formation of potential RNA and TNA nucleoside precursors, amongst other adducts, was observed. View Article: PubMed Central - PubMed Affiliation: School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK. saidul.islam@qmul.ac.uk Show MeSH Major Magnetic Resonance Spectroscopy/methods* Nucleosides/chemistry* Prebiotics* RNA Precursors/analysis* Tetroses/analysis* Minor Chromatography Complex Mixtures Diffusion Molecular Structure Related in: MedlinePlus	© Copyright Policy - open-access Related In: Results - Collection License Show All Figures getmorefigures.php?uid=PMC3814424&req=5 sch01: Synthesis of activated pyrimidine ribonucleotides 1 and 2.

Detection of potential TNA and RNA nucleoside precursors in a prebiotic mixture by pure shift diffusion-ordered NMR spectroscopy.

Islam S, Aguilar JA, Powner MW, Nilsson M, Morris GA, Sutherland JD - Chemistry (2013)

Bottom Line: One potential avenue is the combination of pure shift methodology, in which NMR spectra are measured with greatly improved resolution by suppressing multiplet structure, with diffusion-ordered spectroscopy, in which NMR signals from different species are distinguished through their different rates of diffusion.Such a combination has the added advantage of working with intact mixtures, allowing analyses to be carried out without perturbing mixtures in which chemical entities are part of a network of reactions in equilibrium.The direct formation of potential RNA and TNA nucleoside precursors, amongst other adducts, was observed.

View Article: PubMed Central - PubMed

Affiliation: School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK. saidul.islam@qmul.ac.uk

Show MeSH

Related in: MedlinePlus

Synthesis of activated pyrimidine ribonucleotides 1 and 2.

Related In: Results - Collection

License

Show All Figures

getmorefigures.php?uid=PMC3814424&req=5

sch01: Synthesis of activated pyrimidine ribonucleotides 1 and 2.