Limits...
Comprehensive Approach to Lower Blood Pressure (CALM-BP): a randomized controlled trial of a multifactorial lifestyle intervention.

Ziv A, Vogel O, Keret D, Pintov S, Bodenstein E, Wolkomir K, Doenyas K, Mirovski Y, Efrati S - J Hum Hypertens (2013)

Bottom Line: Medications were reduced if systolic BP dropped below 110 mm Hg accompanied by symptoms.In addition to BP reduction, medications were reduced because of symptomatic hypotension in 70.7% of the CALM-BP group compared with 32.7% in the DASH group, P<0.0001.Significant reductions in body mass index, cholesterol and improved quality-of-life scores were observed only in the CALM-BP group.

View Article: PubMed Central - PubMed

Affiliation: Shiram Integrated Medicine Unit, Assaf Harofeh Medical Center, Zerifin, Israel.

ABSTRACT
Complementary medicine advocates the use of a multifactorial approach to address the varied aspects of hypertension. The aim of this study was to compare the blood pressure (BP) effect and medication use of a novel Comprehensive Approach to Lowering Measured Blood Pressure (CALM-BP), based on complementary medicine principles, with the standard recommended Dietary Approach to Stop Hypertension (DASH). A total of 113 patients treated with antihypertensive drugs were randomly assigned to either CALM-BP treatment (consisting of rice diet, walks, yoga, relaxation and stress management) or to a DASH+exercise control group (consisting of DASH and walks). Ambulatory 24-h and home BP were monitored over a 16-week programme, followed by 6 months of maintenance period. Medications were reduced if systolic BP dropped below 110 mm Hg accompanied by symptoms. In addition to BP reduction, medications were reduced because of symptomatic hypotension in 70.7% of the CALM-BP group compared with 32.7% in the DASH group, P<0.0001. After 6 months, medication status was not altered in the majority of individuals. Significant reductions in body mass index, cholesterol and improved quality-of-life scores were observed only in the CALM-BP group. Lifestyle and diet modifications based on complementary medicine principles are highly effective with respect to BP control, medication use and cardiovascular risk factors.

Show MeSH

Related in: MedlinePlus

Screening, randomization and follow-up. CALM-BP: Comprehensive Approach to Lowering Measured Blood Pressure, based on complementary medicine principles. DASH: the standard recommended Dietary Approach to Stop Hypertension according to the US Department of Health and Human Services, National Institute of Health, National Heart, Lung, and Blood Institute.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3775127&req=5

fig1: Screening, randomization and follow-up. CALM-BP: Comprehensive Approach to Lowering Measured Blood Pressure, based on complementary medicine principles. DASH: the standard recommended Dietary Approach to Stop Hypertension according to the US Department of Health and Human Services, National Institute of Health, National Heart, Lung, and Blood Institute.

Mentions: Initial screening involved 235 individuals of whom 113 were included in the study (Figure 1). The mean age was 57±9 years, and mean body mass index was 29±4 kg m−2; 51% of the participants were women. Baseline ambulatory systolic and diastolic BP values were similar in both groups (Table 2). More participants in DASH group had hyperlipidaemia and were treated with lipid-lowering drugs. No other significant between-group differences were observed (Table 2).


Comprehensive Approach to Lower Blood Pressure (CALM-BP): a randomized controlled trial of a multifactorial lifestyle intervention.

Ziv A, Vogel O, Keret D, Pintov S, Bodenstein E, Wolkomir K, Doenyas K, Mirovski Y, Efrati S - J Hum Hypertens (2013)

Screening, randomization and follow-up. CALM-BP: Comprehensive Approach to Lowering Measured Blood Pressure, based on complementary medicine principles. DASH: the standard recommended Dietary Approach to Stop Hypertension according to the US Department of Health and Human Services, National Institute of Health, National Heart, Lung, and Blood Institute.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3775127&req=5

fig1: Screening, randomization and follow-up. CALM-BP: Comprehensive Approach to Lowering Measured Blood Pressure, based on complementary medicine principles. DASH: the standard recommended Dietary Approach to Stop Hypertension according to the US Department of Health and Human Services, National Institute of Health, National Heart, Lung, and Blood Institute.
Mentions: Initial screening involved 235 individuals of whom 113 were included in the study (Figure 1). The mean age was 57±9 years, and mean body mass index was 29±4 kg m−2; 51% of the participants were women. Baseline ambulatory systolic and diastolic BP values were similar in both groups (Table 2). More participants in DASH group had hyperlipidaemia and were treated with lipid-lowering drugs. No other significant between-group differences were observed (Table 2).

Bottom Line: Medications were reduced if systolic BP dropped below 110 mm Hg accompanied by symptoms.In addition to BP reduction, medications were reduced because of symptomatic hypotension in 70.7% of the CALM-BP group compared with 32.7% in the DASH group, P<0.0001.Significant reductions in body mass index, cholesterol and improved quality-of-life scores were observed only in the CALM-BP group.

View Article: PubMed Central - PubMed

Affiliation: Shiram Integrated Medicine Unit, Assaf Harofeh Medical Center, Zerifin, Israel.

ABSTRACT
Complementary medicine advocates the use of a multifactorial approach to address the varied aspects of hypertension. The aim of this study was to compare the blood pressure (BP) effect and medication use of a novel Comprehensive Approach to Lowering Measured Blood Pressure (CALM-BP), based on complementary medicine principles, with the standard recommended Dietary Approach to Stop Hypertension (DASH). A total of 113 patients treated with antihypertensive drugs were randomly assigned to either CALM-BP treatment (consisting of rice diet, walks, yoga, relaxation and stress management) or to a DASH+exercise control group (consisting of DASH and walks). Ambulatory 24-h and home BP were monitored over a 16-week programme, followed by 6 months of maintenance period. Medications were reduced if systolic BP dropped below 110 mm Hg accompanied by symptoms. In addition to BP reduction, medications were reduced because of symptomatic hypotension in 70.7% of the CALM-BP group compared with 32.7% in the DASH group, P<0.0001. After 6 months, medication status was not altered in the majority of individuals. Significant reductions in body mass index, cholesterol and improved quality-of-life scores were observed only in the CALM-BP group. Lifestyle and diet modifications based on complementary medicine principles are highly effective with respect to BP control, medication use and cardiovascular risk factors.

Show MeSH
Related in: MedlinePlus