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Long-term results of cornea collagen cross-linking with riboflavin for keratoconus.

Agrawal V - Indian J Ophthalmol (2013)

Bottom Line: Visual improvement generally starts 3 months after treatment.Reduction is coma seen on aberrometry in early postoperative phase is also responsible for the improvement in visual acuity.In the light of currently available data we can thus say that CXL is a safe procedure that is successful in arresting keratoconus.

View Article: PubMed Central - PubMed

Affiliation: Consultant Cornea Services, Clear Vision, 201, Bhavya Plaza, Station Road, Khar (W), Mumbai, India.

ABSTRACT
Corneal collagen cross-linking with riboflavin and UVA light (CXL) is the only method designed to arrest the progression of keratoconus. Visual improvement generally starts 3 months after treatment. Reduction is coma seen on aberrometry in early postoperative phase is also responsible for the improvement in visual acuity. In the light of currently available data we can thus say that CXL is a safe procedure that is successful in arresting keratoconus.

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Related in: MedlinePlus

Sequential topography changes seen in one eye of a patient over 31 months. Note the generalized flattening of the cone and the shrinkage of the steepened areas. Also note the change in Best fit sphere as well as the Sim K values. (a) at baseline (b) at 8 months (c) at 20 months and (d) 31 months post-Cross Linking
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Figure 1: Sequential topography changes seen in one eye of a patient over 31 months. Note the generalized flattening of the cone and the shrinkage of the steepened areas. Also note the change in Best fit sphere as well as the Sim K values. (a) at baseline (b) at 8 months (c) at 20 months and (d) 31 months post-Cross Linking

Mentions: Visual improvement generally starts 3 months after treatment.[3] There is a temporary visual reduction seen in the early postoperative phase. This is due to stromal edema evident in 100% of eyes with confocal microscopy.[4] Average visual improvement has been between 1 and 2 Snellen lines from 1 to 4 years after treatment.[56] This is corroborated by our unpublished results over the last 5 years. We have also noted continuing minor changes in topography in patients over time [Fig. 1]. The improved uncorrected visual acuity can be partially explained by reduction in the sphere and the spherical equivalent reduction. Reduction is coma seen on aberrometry in early postoperative phase is also responsible for the improvement in visual acuity.[2] This reduction of values has been maintained up to 36 to 48 months.[5]


Long-term results of cornea collagen cross-linking with riboflavin for keratoconus.

Agrawal V - Indian J Ophthalmol (2013)

Sequential topography changes seen in one eye of a patient over 31 months. Note the generalized flattening of the cone and the shrinkage of the steepened areas. Also note the change in Best fit sphere as well as the Sim K values. (a) at baseline (b) at 8 months (c) at 20 months and (d) 31 months post-Cross Linking
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3775082&req=5

Figure 1: Sequential topography changes seen in one eye of a patient over 31 months. Note the generalized flattening of the cone and the shrinkage of the steepened areas. Also note the change in Best fit sphere as well as the Sim K values. (a) at baseline (b) at 8 months (c) at 20 months and (d) 31 months post-Cross Linking
Mentions: Visual improvement generally starts 3 months after treatment.[3] There is a temporary visual reduction seen in the early postoperative phase. This is due to stromal edema evident in 100% of eyes with confocal microscopy.[4] Average visual improvement has been between 1 and 2 Snellen lines from 1 to 4 years after treatment.[56] This is corroborated by our unpublished results over the last 5 years. We have also noted continuing minor changes in topography in patients over time [Fig. 1]. The improved uncorrected visual acuity can be partially explained by reduction in the sphere and the spherical equivalent reduction. Reduction is coma seen on aberrometry in early postoperative phase is also responsible for the improvement in visual acuity.[2] This reduction of values has been maintained up to 36 to 48 months.[5]

Bottom Line: Visual improvement generally starts 3 months after treatment.Reduction is coma seen on aberrometry in early postoperative phase is also responsible for the improvement in visual acuity.In the light of currently available data we can thus say that CXL is a safe procedure that is successful in arresting keratoconus.

View Article: PubMed Central - PubMed

Affiliation: Consultant Cornea Services, Clear Vision, 201, Bhavya Plaza, Station Road, Khar (W), Mumbai, India.

ABSTRACT
Corneal collagen cross-linking with riboflavin and UVA light (CXL) is the only method designed to arrest the progression of keratoconus. Visual improvement generally starts 3 months after treatment. Reduction is coma seen on aberrometry in early postoperative phase is also responsible for the improvement in visual acuity. In the light of currently available data we can thus say that CXL is a safe procedure that is successful in arresting keratoconus.

Show MeSH
Related in: MedlinePlus