Ichthyosis associated with widespread tinea corporis: report of three cases.
Bottom Line: All of these favor fungal proliferation.They have the ability to obtain nutrients from keratinized material.One of its most prevalent genera is Trichophyton rubrum.
Affiliation: Curitiba(PR), Brazil.
Ichthyoses are a common group of keratinization disorders. A non-inflammatory generalized persistent skin desquamation is observed. It is characterized by increased cell turnover, thickening of the stratum corneum and functional changes of sebaceous and sweat glands. All of these favor fungal proliferation. Dermatophytes may infect skin, hair and nails causing ringworm or tinea. They have the ability to obtain nutrients from keratinized material. One of its most prevalent genera is Trichophyton rubrum. Although tineas and ichthyoses are quite common, the association of the two entities is rarely reported in the literature. Three cases of ichthyosis associated with widespread infection by T. rubrum are presented. Resistance to several antifungal treatments was responsible for worsening of ichthyosis signs and symptoms.
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Mentions: During one of his regular visits in July 2011, he presented ill-defined erythematousscaly papules and plaques on the trunk and upper limbs (Figure 2A). Onycholysis, distal leukonychia, subungualhyperkeratosis and onychorrexis on the toenails were also evident. A mycologicalexamination demonstrated septate hyaline hyphae, and a positive culture forT. rubrum. Skin biopsy presented several hyphae within thestratum corneum, suggesting the diagnosis of dermatophytosis (Figure 2B). A subungual sample also demonstrated T. rubrum.Patient was treated with terbinafine 250 mg qd for 120 days, with significantimprovement of skin scaling and nail dystrophy (Figures 2C and 2D).