Limits...
Magnetoresistive emulsion analyzer.

Lin G, Baraban L, Han L, Karnaushenko D, Makarov D, Cuniberti G, Schmidt OG - Sci Rep (2013)

Bottom Line: We realize a magnetoresistive emulsion analyzer capable of detection, multiparametric analysis and sorting of ferrofluid-containing nanoliter-droplets.The operation of the device in a cytometric mode provides high throughput and quantitative information about the dimensions and magnetic content of the emulsion.Our method offers important complementarity to conventional optical approaches involving ferrofluids, and paves the way to the development of novel compact tools for diagnostics and nanomedicine including drug design and screening.

View Article: PubMed Central - PubMed

Affiliation: Institute for Integrative Nanosciences, IFW Dresden, Helmholtzstrasse 20, Dresden, Germany.

ABSTRACT
We realize a magnetoresistive emulsion analyzer capable of detection, multiparametric analysis and sorting of ferrofluid-containing nanoliter-droplets. The operation of the device in a cytometric mode provides high throughput and quantitative information about the dimensions and magnetic content of the emulsion. Our method offers important complementarity to conventional optical approaches involving ferrofluids, and paves the way to the development of novel compact tools for diagnostics and nanomedicine including drug design and screening.

Show MeSH
(a) Concept of GMR-based droplet analyzer for multiparametric analysis and sorting. (b) Magnetoresistive characterization of GMR sensor. Inset: Photograph of the patterned sensor prepared for measurements in 4-point configuration. (c) Real time detection of a train containing small and large ferrofluid emulsion droplets. Sorting of small (d1) and large (d2) droplets at the T-junction.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3757360&req=5

f1: (a) Concept of GMR-based droplet analyzer for multiparametric analysis and sorting. (b) Magnetoresistive characterization of GMR sensor. Inset: Photograph of the patterned sensor prepared for measurements in 4-point configuration. (c) Real time detection of a train containing small and large ferrofluid emulsion droplets. Sorting of small (d1) and large (d2) droplets at the T-junction.

Mentions: The concept of the magnetoresistive emulsion analyzer capable of multiparametric studies and sorting of ferrofluid droplets is presented in Figure 1a. Water-in-oil emulsion droplets of various sizes with encapsulated ferrofluids are produced in a T-junction geometry. An example of the flow profiles of the two immiscible phases is displayed in Supplementary Figure 6.


Magnetoresistive emulsion analyzer.

Lin G, Baraban L, Han L, Karnaushenko D, Makarov D, Cuniberti G, Schmidt OG - Sci Rep (2013)

(a) Concept of GMR-based droplet analyzer for multiparametric analysis and sorting. (b) Magnetoresistive characterization of GMR sensor. Inset: Photograph of the patterned sensor prepared for measurements in 4-point configuration. (c) Real time detection of a train containing small and large ferrofluid emulsion droplets. Sorting of small (d1) and large (d2) droplets at the T-junction.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3757360&req=5

f1: (a) Concept of GMR-based droplet analyzer for multiparametric analysis and sorting. (b) Magnetoresistive characterization of GMR sensor. Inset: Photograph of the patterned sensor prepared for measurements in 4-point configuration. (c) Real time detection of a train containing small and large ferrofluid emulsion droplets. Sorting of small (d1) and large (d2) droplets at the T-junction.
Mentions: The concept of the magnetoresistive emulsion analyzer capable of multiparametric studies and sorting of ferrofluid droplets is presented in Figure 1a. Water-in-oil emulsion droplets of various sizes with encapsulated ferrofluids are produced in a T-junction geometry. An example of the flow profiles of the two immiscible phases is displayed in Supplementary Figure 6.

Bottom Line: We realize a magnetoresistive emulsion analyzer capable of detection, multiparametric analysis and sorting of ferrofluid-containing nanoliter-droplets.The operation of the device in a cytometric mode provides high throughput and quantitative information about the dimensions and magnetic content of the emulsion.Our method offers important complementarity to conventional optical approaches involving ferrofluids, and paves the way to the development of novel compact tools for diagnostics and nanomedicine including drug design and screening.

View Article: PubMed Central - PubMed

Affiliation: Institute for Integrative Nanosciences, IFW Dresden, Helmholtzstrasse 20, Dresden, Germany.

ABSTRACT
We realize a magnetoresistive emulsion analyzer capable of detection, multiparametric analysis and sorting of ferrofluid-containing nanoliter-droplets. The operation of the device in a cytometric mode provides high throughput and quantitative information about the dimensions and magnetic content of the emulsion. Our method offers important complementarity to conventional optical approaches involving ferrofluids, and paves the way to the development of novel compact tools for diagnostics and nanomedicine including drug design and screening.

Show MeSH