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Improvement of atopic dermatitis severity after reducing indoor air pollutants.

Kim HO, Kim JH, Cho SI, Chung BY, Ahn IS, Lee CH, Park CW - Ann Dermatol (2013)

Bottom Line: Subsequent to the completion of the indoor air quality improvement program, the mean PM10 level was significantly decreased from 182.7 to 73.4 µg/m(3).The mean number of hospital visits decreased from 1.3 per month during the first survey to 0.7 per month during the second survey, which was statistically significant.The reduction of PM10 through improving indoor air quality should be considered in kindergartens and schools in order to prevent and relieve AD in children.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Kangnam Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Korea.

ABSTRACT

Background: Recent epidemiologic studies have shown that environmental contaminants such as air pollution and tobacco smoke play an important role in the pathophysiology of atopic dermatitis (AD).

Objective: The aim of this study was to evaluate the relationship between the severity of AD and indoor air pollution.

Methods: The study population consisted of 425 children from 9 kindergartens, Korea. The authors surveyed the prevalence of AD and evaluated disease severity by the eczema area and severity index (EASI) score and investigator's global assessment (IGA). After measuring indoor air pollution, a program to improve indoor air quality was conducted in 9 kindergartens. Seven months later, the prevalence and disease severity were evaluated.

Results: The initial prevalence of AD was 8% and the mean EASI score was 2.37. The levels of particulate material 10 (PM10) and carbon dioxide (CO2) were higher in some kindergartens compared to the normal values. Subsequent to the completion of the indoor air quality improvement program, the mean PM10 level was significantly decreased from 182.7 to 73.4 µg/m(3). After the completion of the program, the prevalence of AD and the mean EASI were decreased, and the changes were both statistically significant. The mean number of hospital visits decreased from 1.3 per month during the first survey to 0.7 per month during the second survey, which was statistically significant.

Conclusion: Indoor air pollution could be related to AD. The reduction of PM10 through improving indoor air quality should be considered in kindergartens and schools in order to prevent and relieve AD in children.

No MeSH data available.


Related in: MedlinePlus

The comparison of atopic dermatitis improvement and the EASI score between the first and second surveys at 9 different kindergartens (A to I). The mean EASI score decreased from 2.37 in the first survey to 1.19 in the second survey (p<0.05). All kindergartens except 1 showed a decrease in the EASI score during the second survey. EASI: eczema area and severity index.
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Figure 1: The comparison of atopic dermatitis improvement and the EASI score between the first and second surveys at 9 different kindergartens (A to I). The mean EASI score decreased from 2.37 in the first survey to 1.19 in the second survey (p<0.05). All kindergartens except 1 showed a decrease in the EASI score during the second survey. EASI: eczema area and severity index.

Mentions: The mean EASI score decreased from 2.37±1.08 in the first survey to 1.19±1.25 in the second survey (Fig. 1), and the difference was statistically significant (p<0.05).


Improvement of atopic dermatitis severity after reducing indoor air pollutants.

Kim HO, Kim JH, Cho SI, Chung BY, Ahn IS, Lee CH, Park CW - Ann Dermatol (2013)

The comparison of atopic dermatitis improvement and the EASI score between the first and second surveys at 9 different kindergartens (A to I). The mean EASI score decreased from 2.37 in the first survey to 1.19 in the second survey (p<0.05). All kindergartens except 1 showed a decrease in the EASI score during the second survey. EASI: eczema area and severity index.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3756192&req=5

Figure 1: The comparison of atopic dermatitis improvement and the EASI score between the first and second surveys at 9 different kindergartens (A to I). The mean EASI score decreased from 2.37 in the first survey to 1.19 in the second survey (p<0.05). All kindergartens except 1 showed a decrease in the EASI score during the second survey. EASI: eczema area and severity index.
Mentions: The mean EASI score decreased from 2.37±1.08 in the first survey to 1.19±1.25 in the second survey (Fig. 1), and the difference was statistically significant (p<0.05).

Bottom Line: Subsequent to the completion of the indoor air quality improvement program, the mean PM10 level was significantly decreased from 182.7 to 73.4 µg/m(3).The mean number of hospital visits decreased from 1.3 per month during the first survey to 0.7 per month during the second survey, which was statistically significant.The reduction of PM10 through improving indoor air quality should be considered in kindergartens and schools in order to prevent and relieve AD in children.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Kangnam Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Korea.

ABSTRACT

Background: Recent epidemiologic studies have shown that environmental contaminants such as air pollution and tobacco smoke play an important role in the pathophysiology of atopic dermatitis (AD).

Objective: The aim of this study was to evaluate the relationship between the severity of AD and indoor air pollution.

Methods: The study population consisted of 425 children from 9 kindergartens, Korea. The authors surveyed the prevalence of AD and evaluated disease severity by the eczema area and severity index (EASI) score and investigator's global assessment (IGA). After measuring indoor air pollution, a program to improve indoor air quality was conducted in 9 kindergartens. Seven months later, the prevalence and disease severity were evaluated.

Results: The initial prevalence of AD was 8% and the mean EASI score was 2.37. The levels of particulate material 10 (PM10) and carbon dioxide (CO2) were higher in some kindergartens compared to the normal values. Subsequent to the completion of the indoor air quality improvement program, the mean PM10 level was significantly decreased from 182.7 to 73.4 µg/m(3). After the completion of the program, the prevalence of AD and the mean EASI were decreased, and the changes were both statistically significant. The mean number of hospital visits decreased from 1.3 per month during the first survey to 0.7 per month during the second survey, which was statistically significant.

Conclusion: Indoor air pollution could be related to AD. The reduction of PM10 through improving indoor air quality should be considered in kindergartens and schools in order to prevent and relieve AD in children.

No MeSH data available.


Related in: MedlinePlus