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Cutaneous leukocytoclastic vasculitis in the presence of methimazole therapy.

Ribeiro Cde O, Magrin PF, Vilar EA, Durães SM, Estrella RR - An Bras Dermatol (2013 Mar-Apr)

Bottom Line: Treatment with antithyroid drugs may be accompanied by side effects.We present a patient diagnosed with Grave's Disease who developed extensive vasculitis in the lower limbs during methimazole use.After suspension of the methimazole and the introduction of prednisone in immunesupressor doses the cutaneous lesions started to involute.

View Article: PubMed Central - PubMed

Affiliation: Dermatology Department, Antônio Pedro University Hospital, Universidade Federal Fluminense, Niterói, (RJ), Brazil. carla_ribb@yahoo.com.br

ABSTRACT
Treatment with antithyroid drugs may be accompanied by side effects. We present a patient diagnosed with Grave's Disease who developed extensive vasculitis in the lower limbs during methimazole use. After suspension of the methimazole and the introduction of prednisone in immunesupressor doses the cutaneous lesions started to involute.

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Regression of skin lesions
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f05: Regression of skin lesions

Mentions: In view of the tests feedback, we decided to discontinue MTM and start therapy withprednisone (1mg/kg). We were able to observe continuous improvement after 7 days (Figure 5).


Cutaneous leukocytoclastic vasculitis in the presence of methimazole therapy.

Ribeiro Cde O, Magrin PF, Vilar EA, Durães SM, Estrella RR - An Bras Dermatol (2013 Mar-Apr)

Regression of skin lesions
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3750899&req=5

f05: Regression of skin lesions
Mentions: In view of the tests feedback, we decided to discontinue MTM and start therapy withprednisone (1mg/kg). We were able to observe continuous improvement after 7 days (Figure 5).

Bottom Line: Treatment with antithyroid drugs may be accompanied by side effects.We present a patient diagnosed with Grave's Disease who developed extensive vasculitis in the lower limbs during methimazole use.After suspension of the methimazole and the introduction of prednisone in immunesupressor doses the cutaneous lesions started to involute.

View Article: PubMed Central - PubMed

Affiliation: Dermatology Department, Antônio Pedro University Hospital, Universidade Federal Fluminense, Niterói, (RJ), Brazil. carla_ribb@yahoo.com.br

ABSTRACT
Treatment with antithyroid drugs may be accompanied by side effects. We present a patient diagnosed with Grave's Disease who developed extensive vasculitis in the lower limbs during methimazole use. After suspension of the methimazole and the introduction of prednisone in immunesupressor doses the cutaneous lesions started to involute.

Show MeSH
Related in: MedlinePlus