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American tegumentary leishmaniasis: an uncommon clinical and histopathological presentation.

Adriano AL, Leal PA, Breckenfeld MP, Costa Idos S, Almeida C, Sousa AR - An Bras Dermatol (2013 Mar-Apr)

Bottom Line: We report a case of an unusual presentation of American Tegumentary Leishmaniasis involving a male patient with a solitary lesion on the ear lobe, persisting with minimal increase for at least six months without ulceration or related symptoms.Treatment commenced with meglumine antimoniate resulting in regression of the condition.This report is of importance given the unusual clinical manifestation and histopathological findings in this case and the fact that there was low correlation with the extended duration of the disease.

View Article: PubMed Central - PubMed

Affiliation: Dermatology Department, Dona Libânia Dermatology Center, Fortaleza, CE, Brazil. adrilena@hotmail.com

ABSTRACT
We report a case of an unusual presentation of American Tegumentary Leishmaniasis involving a male patient with a solitary lesion on the ear lobe, persisting with minimal increase for at least six months without ulceration or related symptoms. The histological sections showed epithelial atrophy and a large number of structures consistent with Leishmania sp. amastigotes within macrophages. Treatment commenced with meglumine antimoniate resulting in regression of the condition. This report is of importance given the unusual clinical manifestation and histopathological findings in this case and the fact that there was low correlation with the extended duration of the disease.

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Regression of the lesion four months after the end of the therapy
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f04: Regression of the lesion four months after the end of the therapy

Mentions: The patient missed follow-up but returned three months later with no changes on thelesion. Since no abnormalities were found in the general laboratory tests, treatment wasstarted with meglumine antimoniate (15mg/kg) over 20 days. Two months after the end oftherapy the lesions showed clear signs of regression (Figure 4).


American tegumentary leishmaniasis: an uncommon clinical and histopathological presentation.

Adriano AL, Leal PA, Breckenfeld MP, Costa Idos S, Almeida C, Sousa AR - An Bras Dermatol (2013 Mar-Apr)

Regression of the lesion four months after the end of the therapy
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3750893&req=5

f04: Regression of the lesion four months after the end of the therapy
Mentions: The patient missed follow-up but returned three months later with no changes on thelesion. Since no abnormalities were found in the general laboratory tests, treatment wasstarted with meglumine antimoniate (15mg/kg) over 20 days. Two months after the end oftherapy the lesions showed clear signs of regression (Figure 4).

Bottom Line: We report a case of an unusual presentation of American Tegumentary Leishmaniasis involving a male patient with a solitary lesion on the ear lobe, persisting with minimal increase for at least six months without ulceration or related symptoms.Treatment commenced with meglumine antimoniate resulting in regression of the condition.This report is of importance given the unusual clinical manifestation and histopathological findings in this case and the fact that there was low correlation with the extended duration of the disease.

View Article: PubMed Central - PubMed

Affiliation: Dermatology Department, Dona Libânia Dermatology Center, Fortaleza, CE, Brazil. adrilena@hotmail.com

ABSTRACT
We report a case of an unusual presentation of American Tegumentary Leishmaniasis involving a male patient with a solitary lesion on the ear lobe, persisting with minimal increase for at least six months without ulceration or related symptoms. The histological sections showed epithelial atrophy and a large number of structures consistent with Leishmania sp. amastigotes within macrophages. Treatment commenced with meglumine antimoniate resulting in regression of the condition. This report is of importance given the unusual clinical manifestation and histopathological findings in this case and the fact that there was low correlation with the extended duration of the disease.

Show MeSH
Related in: MedlinePlus