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American tegumentary leishmaniasis: an uncommon clinical and histopathological presentation.

Adriano AL, Leal PA, Breckenfeld MP, Costa Idos S, Almeida C, Sousa AR - An Bras Dermatol (2013 Mar-Apr)

Bottom Line: We report a case of an unusual presentation of American Tegumentary Leishmaniasis involving a male patient with a solitary lesion on the ear lobe, persisting with minimal increase for at least six months without ulceration or related symptoms.Treatment commenced with meglumine antimoniate resulting in regression of the condition.This report is of importance given the unusual clinical manifestation and histopathological findings in this case and the fact that there was low correlation with the extended duration of the disease.

View Article: PubMed Central - PubMed

Affiliation: Dermatology Department, Dona Libânia Dermatology Center, Fortaleza, CE, Brazil. adrilena@hotmail.com

ABSTRACT
We report a case of an unusual presentation of American Tegumentary Leishmaniasis involving a male patient with a solitary lesion on the ear lobe, persisting with minimal increase for at least six months without ulceration or related symptoms. The histological sections showed epithelial atrophy and a large number of structures consistent with Leishmania sp. amastigotes within macrophages. Treatment commenced with meglumine antimoniate resulting in regression of the condition. This report is of importance given the unusual clinical manifestation and histopathological findings in this case and the fact that there was low correlation with the extended duration of the disease.

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There is a large number of leishmania amastigotes within macrophages.
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f03: There is a large number of leishmania amastigotes within macrophages.

Mentions: The histological sections showed epithelial atrophy, and Grenz's zone in the dermis,with a dense superficial and deep lymphoplasmacytic and histiocytic infiltrate. A largenumber of structures consistent with Leishmania sp. amastigotes wasobserved in macrophages. The results of the Leishmanin skin test (LST) were positive,with 10 mm of induration (Figure 2 and 3).


American tegumentary leishmaniasis: an uncommon clinical and histopathological presentation.

Adriano AL, Leal PA, Breckenfeld MP, Costa Idos S, Almeida C, Sousa AR - An Bras Dermatol (2013 Mar-Apr)

There is a large number of leishmania amastigotes within macrophages.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3750893&req=5

f03: There is a large number of leishmania amastigotes within macrophages.
Mentions: The histological sections showed epithelial atrophy, and Grenz's zone in the dermis,with a dense superficial and deep lymphoplasmacytic and histiocytic infiltrate. A largenumber of structures consistent with Leishmania sp. amastigotes wasobserved in macrophages. The results of the Leishmanin skin test (LST) were positive,with 10 mm of induration (Figure 2 and 3).

Bottom Line: We report a case of an unusual presentation of American Tegumentary Leishmaniasis involving a male patient with a solitary lesion on the ear lobe, persisting with minimal increase for at least six months without ulceration or related symptoms.Treatment commenced with meglumine antimoniate resulting in regression of the condition.This report is of importance given the unusual clinical manifestation and histopathological findings in this case and the fact that there was low correlation with the extended duration of the disease.

View Article: PubMed Central - PubMed

Affiliation: Dermatology Department, Dona Libânia Dermatology Center, Fortaleza, CE, Brazil. adrilena@hotmail.com

ABSTRACT
We report a case of an unusual presentation of American Tegumentary Leishmaniasis involving a male patient with a solitary lesion on the ear lobe, persisting with minimal increase for at least six months without ulceration or related symptoms. The histological sections showed epithelial atrophy and a large number of structures consistent with Leishmania sp. amastigotes within macrophages. Treatment commenced with meglumine antimoniate resulting in regression of the condition. This report is of importance given the unusual clinical manifestation and histopathological findings in this case and the fact that there was low correlation with the extended duration of the disease.

Show MeSH
Related in: MedlinePlus