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Physical activity and mortality in a prospective cohort of middle-aged and elderly men - a time perspective.

Bellavia A, Bottai M, Wolk A, Orsini N - Int J Behav Nutr Phys Act (2013)

Bottom Line: We found a strong evidence of non-linearity between TPA and the 10th survival percentile (P-value < 0.001).Above the median TPA additional activity was not significantly associated with better survival.We found that a physically active lifestyle is associated with a substantial improvement in survival time, up to 2.5 years over 13 years of follow-up.

View Article: PubMed Central - HTML - PubMed

Affiliation: Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. andrea.bellavia@ki.se

ABSTRACT

Background: Higher physical activity (PA) levels are known to be associated with lower risk of death. Less attention, however, has been paid to directly evaluate the effect of PA on the time by which a certain fraction of the population has died.

Methods: A population-based cohort of 29,362 men 45 to 79 years of age was followed from January 1998 to December 2010. A total of 4,570 men died. PA was assessed through a self-administrated questionnaire. Adjusted differences in the number of months by which 10% (10th percentile) of the cohort has died, according to levels of total PA (TPA) and different domains of PA were estimated using Laplace regression.

Results: Overall, the 10th survival percentile was 9.6 years, that is, 90% of the cohort lived longer than 9.6 years. We found a strong evidence of non-linearity between TPA and the 10th survival percentile (P-value < 0.001). Compared to men with the lowest TPA (29 metabolic equivalents (MET)-hrs/day), men with a median TPA (41 MET-hrs/day) had 30 months longer survival (95% CI: 25-35). Below the median TPA, every increment of 4 MET-hrs/day, approximately a 30 minutes brisk pace daily walk, was associated with a longer survival of 11 months (95% CI: 8-15). Above the median TPA additional activity was not significantly associated with better survival.

Conclusions: We found that a physically active lifestyle is associated with a substantial improvement in survival time, up to 2.5 years over 13 years of follow-up.

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Related in: MedlinePlus

Survival percentiles (proportion of the cohort who has died) among the group of inactive participants (solid line, walking/bicycling-hardly ever, exercise- < 1 h/week, tv watching/reading > 3 h/day, work occupation-mostly sitting) and the group of participants active in different activities (dashed line, else) estimated with multivariable Laplace regression. The estimates were adjusted for baseline age, body mass index, alcohol consumption, smoking status and educational level; in the graph these covariates are fixed on the most frequent category (Age: 50–54 years, Smoking: ex-smokers with less than 20 pack for week, Alcohol: 10-20 g/day, BMI: 25-29 kg m-2, Education: 1–9 years).
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Figure 3: Survival percentiles (proportion of the cohort who has died) among the group of inactive participants (solid line, walking/bicycling-hardly ever, exercise- < 1 h/week, tv watching/reading > 3 h/day, work occupation-mostly sitting) and the group of participants active in different activities (dashed line, else) estimated with multivariable Laplace regression. The estimates were adjusted for baseline age, body mass index, alcohol consumption, smoking status and educational level; in the graph these covariates are fixed on the most frequent category (Age: 50–54 years, Smoking: ex-smokers with less than 20 pack for week, Alcohol: 10-20 g/day, BMI: 25-29 kg m-2, Education: 1–9 years).

Mentions: We next compared the group of inactive participants (hardly ever walk or bike, exercise less than 1 hours per week, sitting watching TV/reading 3 hours per day or more, mostly sitting at work, and less than 1 hour per day of home/household work) and the group of participants who were active in the different kinds of daily activity (engaged in leisure time walking/bicycling, exercise more than 1 hours per week, limited leisure time inactivity - watching TV/reading - to less than 3 hours per day, physically active at work, and more than 1 hour per day of home/household work) (Figure 3). Active men lived 31 months longer than those men who were inactive (95% CI: 23–39). The difference in survival was not limited to the 10th percentile but was substantial throughout the 13 years of follow-up, ranging from 25 months for the 5th percentile (95% CI: 15–34) to 33 months for the 15th percentile (95% CI: 25–40).


Physical activity and mortality in a prospective cohort of middle-aged and elderly men - a time perspective.

Bellavia A, Bottai M, Wolk A, Orsini N - Int J Behav Nutr Phys Act (2013)

Survival percentiles (proportion of the cohort who has died) among the group of inactive participants (solid line, walking/bicycling-hardly ever, exercise- < 1 h/week, tv watching/reading > 3 h/day, work occupation-mostly sitting) and the group of participants active in different activities (dashed line, else) estimated with multivariable Laplace regression. The estimates were adjusted for baseline age, body mass index, alcohol consumption, smoking status and educational level; in the graph these covariates are fixed on the most frequent category (Age: 50–54 years, Smoking: ex-smokers with less than 20 pack for week, Alcohol: 10-20 g/day, BMI: 25-29 kg m-2, Education: 1–9 years).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3750581&req=5

Figure 3: Survival percentiles (proportion of the cohort who has died) among the group of inactive participants (solid line, walking/bicycling-hardly ever, exercise- < 1 h/week, tv watching/reading > 3 h/day, work occupation-mostly sitting) and the group of participants active in different activities (dashed line, else) estimated with multivariable Laplace regression. The estimates were adjusted for baseline age, body mass index, alcohol consumption, smoking status and educational level; in the graph these covariates are fixed on the most frequent category (Age: 50–54 years, Smoking: ex-smokers with less than 20 pack for week, Alcohol: 10-20 g/day, BMI: 25-29 kg m-2, Education: 1–9 years).
Mentions: We next compared the group of inactive participants (hardly ever walk or bike, exercise less than 1 hours per week, sitting watching TV/reading 3 hours per day or more, mostly sitting at work, and less than 1 hour per day of home/household work) and the group of participants who were active in the different kinds of daily activity (engaged in leisure time walking/bicycling, exercise more than 1 hours per week, limited leisure time inactivity - watching TV/reading - to less than 3 hours per day, physically active at work, and more than 1 hour per day of home/household work) (Figure 3). Active men lived 31 months longer than those men who were inactive (95% CI: 23–39). The difference in survival was not limited to the 10th percentile but was substantial throughout the 13 years of follow-up, ranging from 25 months for the 5th percentile (95% CI: 15–34) to 33 months for the 15th percentile (95% CI: 25–40).

Bottom Line: We found a strong evidence of non-linearity between TPA and the 10th survival percentile (P-value < 0.001).Above the median TPA additional activity was not significantly associated with better survival.We found that a physically active lifestyle is associated with a substantial improvement in survival time, up to 2.5 years over 13 years of follow-up.

View Article: PubMed Central - HTML - PubMed

Affiliation: Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. andrea.bellavia@ki.se

ABSTRACT

Background: Higher physical activity (PA) levels are known to be associated with lower risk of death. Less attention, however, has been paid to directly evaluate the effect of PA on the time by which a certain fraction of the population has died.

Methods: A population-based cohort of 29,362 men 45 to 79 years of age was followed from January 1998 to December 2010. A total of 4,570 men died. PA was assessed through a self-administrated questionnaire. Adjusted differences in the number of months by which 10% (10th percentile) of the cohort has died, according to levels of total PA (TPA) and different domains of PA were estimated using Laplace regression.

Results: Overall, the 10th survival percentile was 9.6 years, that is, 90% of the cohort lived longer than 9.6 years. We found a strong evidence of non-linearity between TPA and the 10th survival percentile (P-value < 0.001). Compared to men with the lowest TPA (29 metabolic equivalents (MET)-hrs/day), men with a median TPA (41 MET-hrs/day) had 30 months longer survival (95% CI: 25-35). Below the median TPA, every increment of 4 MET-hrs/day, approximately a 30 minutes brisk pace daily walk, was associated with a longer survival of 11 months (95% CI: 8-15). Above the median TPA additional activity was not significantly associated with better survival.

Conclusions: We found that a physically active lifestyle is associated with a substantial improvement in survival time, up to 2.5 years over 13 years of follow-up.

Show MeSH
Related in: MedlinePlus