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Efficacy to effectiveness transition of an Educational Program to Increase Colorectal Cancer Screening (EPICS): study protocol of a cluster randomized controlled trial.

Smith SA, Blumenthal DS - Implement Sci (2013)

Bottom Line: African Americans have the highest incidence and mortality and are less likely than whites to have been screened for colorectal cancer (CRC).This study aims to identify the most efficacious approach to disseminate an evidence-based intervention in promoting colorectal screening in African Americans and to identify the factors associated with its efficacy.Cost-effectiveness analysis will be conducted.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Community Health and Preventive Medicine, Morehouse School of Medicine, Atlanta, GA, USA. ssmith@msm.edu

ABSTRACT

Background: African Americans have the highest incidence and mortality and are less likely than whites to have been screened for colorectal cancer (CRC). Many interventions have been shown to increase CRC screening in research settings, but few have been evaluated specifically for use in African-American communities in real world settings. This study aims to identify the most efficacious approach to disseminate an evidence-based intervention in promoting colorectal screening in African Americans and to identify the factors associated with its efficacy.

Methods/design: In this study, investigators will recruit 20 community coalitions and 7,200 African-Americans age 50 to 74 to test passive and active approaches to disseminating the Educational Program to Increase Colorectal Cancer Screening (EPICS); to measure the extent to which EPICS is accepted and the fidelity of implementation in various settings and to estimate the potential translatability and public health impact of EPICS. This four-arm cluster randomized trial compares the following implementation strategies: passive arms, (web access to facilitator training materials and toolkits without technical assistance (TA) and (web access, but with technical assistance (TA); active arms, (in-person access to facilitator training materials and toolkits without TA and (in-person access with TA). Primary outcome measures are the reach (the proportion of representative community coalitions and individuals participating) and efficacy (post-intervention changes in CRC screening rates). Secondary outcomes include adoption (percentage of community coalitions implementing the EPICS sessions) and implementation (quality and consistency of the intervention delivery). The extent to which community coalitions continue to implement EPICS post-implementation (maintenance) will also be measured. Cost-effectiveness analysis will be conducted.

Discussion: Implementing EPICS in partnership with community coalitions, we hypothesized, will result in more rapid adoption than traditional top-down approaches, and resulting changes in community CRC screening practices are more likely to be sustainable over time. With its national reach, this study has the potential to enhance our understanding of barriers and enablers to the uptake of educational programs aimed at eliminating cancer disparities.

Trial registration: http://www.ClinicalTrials.gov NCT01805622.

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Related in: MedlinePlus

CONSORT flow diagram for EPICS cRCT.
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Related In: Results  -  Collection

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Figure 1: CONSORT flow diagram for EPICS cRCT.

Mentions: This study is a four-arm, cluster randomized controlled trial (cRCT). FigureĀ 1 depicts information from four stages of the EPICS cRCT (enrollment, intervention allocation, follow-up, and analysis) based on the recommended flow of parallel group randomized trials [12].


Efficacy to effectiveness transition of an Educational Program to Increase Colorectal Cancer Screening (EPICS): study protocol of a cluster randomized controlled trial.

Smith SA, Blumenthal DS - Implement Sci (2013)

CONSORT flow diagram for EPICS cRCT.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3750535&req=5

Figure 1: CONSORT flow diagram for EPICS cRCT.
Mentions: This study is a four-arm, cluster randomized controlled trial (cRCT). FigureĀ 1 depicts information from four stages of the EPICS cRCT (enrollment, intervention allocation, follow-up, and analysis) based on the recommended flow of parallel group randomized trials [12].

Bottom Line: African Americans have the highest incidence and mortality and are less likely than whites to have been screened for colorectal cancer (CRC).This study aims to identify the most efficacious approach to disseminate an evidence-based intervention in promoting colorectal screening in African Americans and to identify the factors associated with its efficacy.Cost-effectiveness analysis will be conducted.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Community Health and Preventive Medicine, Morehouse School of Medicine, Atlanta, GA, USA. ssmith@msm.edu

ABSTRACT

Background: African Americans have the highest incidence and mortality and are less likely than whites to have been screened for colorectal cancer (CRC). Many interventions have been shown to increase CRC screening in research settings, but few have been evaluated specifically for use in African-American communities in real world settings. This study aims to identify the most efficacious approach to disseminate an evidence-based intervention in promoting colorectal screening in African Americans and to identify the factors associated with its efficacy.

Methods/design: In this study, investigators will recruit 20 community coalitions and 7,200 African-Americans age 50 to 74 to test passive and active approaches to disseminating the Educational Program to Increase Colorectal Cancer Screening (EPICS); to measure the extent to which EPICS is accepted and the fidelity of implementation in various settings and to estimate the potential translatability and public health impact of EPICS. This four-arm cluster randomized trial compares the following implementation strategies: passive arms, (web access to facilitator training materials and toolkits without technical assistance (TA) and (web access, but with technical assistance (TA); active arms, (in-person access to facilitator training materials and toolkits without TA and (in-person access with TA). Primary outcome measures are the reach (the proportion of representative community coalitions and individuals participating) and efficacy (post-intervention changes in CRC screening rates). Secondary outcomes include adoption (percentage of community coalitions implementing the EPICS sessions) and implementation (quality and consistency of the intervention delivery). The extent to which community coalitions continue to implement EPICS post-implementation (maintenance) will also be measured. Cost-effectiveness analysis will be conducted.

Discussion: Implementing EPICS in partnership with community coalitions, we hypothesized, will result in more rapid adoption than traditional top-down approaches, and resulting changes in community CRC screening practices are more likely to be sustainable over time. With its national reach, this study has the potential to enhance our understanding of barriers and enablers to the uptake of educational programs aimed at eliminating cancer disparities.

Trial registration: http://www.ClinicalTrials.gov NCT01805622.

Show MeSH
Related in: MedlinePlus