Limits...
Ventricular tachycardia - an atypical initial presentation of sarcoidosis: a case report.

Ekka M, Sinha S, Purushothaman R, Naik N, Narang R, Singh L - J Med Case Rep (2013)

Bottom Line: Although clinically apparent cardiac sarcoidosis is an uncommon entity, ventricular tachyarrhythmias as the first presenting symptom are very rare.We discuss the case of a 41-year-old Asian woman who presented to our hospital with intermittent palpitation and on evaluation was diagnosed to have systemic sarcoidosis with cardiac involvement.She was started on multiple antiarrhythmic drugs and corticosteroids without any satisfactory response.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Medicine, All India Institute of Medical Sciences, New Delhi, India. drsanjeevsinha2002@yahoo.com.

ABSTRACT

Introduction: Symptomatic cardiac involvement is seen in less than 5% of all cases of sarcoidosis. Although clinically apparent cardiac sarcoidosis is an uncommon entity, ventricular tachyarrhythmias as the first presenting symptom are very rare.

Case presentation: We discuss the case of a 41-year-old Asian woman who presented to our hospital with intermittent palpitation and on evaluation was diagnosed to have systemic sarcoidosis with cardiac involvement. She was started on multiple antiarrhythmic drugs and corticosteroids without any satisfactory response.

Conclusions: Our case report indicates that sarcoidosis can manifest as ventricular tachycardia without any detectable systemic findings. This makes sarcoidosis an important diagnostic consideration in patients with ventricular tachycardia of unknown origin given the high mortality associated with ventricular tachyarrhythmias.

No MeSH data available.


Related in: MedlinePlus

Electrocardiogram showing monomorphic ventricular tachycardia.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3750302&req=5

Figure 2: Electrocardiogram showing monomorphic ventricular tachycardia.

Mentions: On investigation, her hemogram, blood biochemistry, liver, renal function and thyroid function were within normal limits. Her angiotensin-converting enzyme level was 147μL (normal range: 0 to 20). Her serum calcium was normal. Her immunological markers were negative with normal erythrocyte sedimentation rate and C-reactive protein. A contrast-enhanced computed tomography (CT) chest scan showed findings suggestive of stage-III sarcoidosis (Figure 1). A slit lamp examination of her eyes did not reveal any abnormal findings. An electrocardiogram showed monomorphic VT and right bundle branch block with right axis deviation (Figure 2).


Ventricular tachycardia - an atypical initial presentation of sarcoidosis: a case report.

Ekka M, Sinha S, Purushothaman R, Naik N, Narang R, Singh L - J Med Case Rep (2013)

Electrocardiogram showing monomorphic ventricular tachycardia.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3750302&req=5

Figure 2: Electrocardiogram showing monomorphic ventricular tachycardia.
Mentions: On investigation, her hemogram, blood biochemistry, liver, renal function and thyroid function were within normal limits. Her angiotensin-converting enzyme level was 147μL (normal range: 0 to 20). Her serum calcium was normal. Her immunological markers were negative with normal erythrocyte sedimentation rate and C-reactive protein. A contrast-enhanced computed tomography (CT) chest scan showed findings suggestive of stage-III sarcoidosis (Figure 1). A slit lamp examination of her eyes did not reveal any abnormal findings. An electrocardiogram showed monomorphic VT and right bundle branch block with right axis deviation (Figure 2).

Bottom Line: Although clinically apparent cardiac sarcoidosis is an uncommon entity, ventricular tachyarrhythmias as the first presenting symptom are very rare.We discuss the case of a 41-year-old Asian woman who presented to our hospital with intermittent palpitation and on evaluation was diagnosed to have systemic sarcoidosis with cardiac involvement.She was started on multiple antiarrhythmic drugs and corticosteroids without any satisfactory response.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Medicine, All India Institute of Medical Sciences, New Delhi, India. drsanjeevsinha2002@yahoo.com.

ABSTRACT

Introduction: Symptomatic cardiac involvement is seen in less than 5% of all cases of sarcoidosis. Although clinically apparent cardiac sarcoidosis is an uncommon entity, ventricular tachyarrhythmias as the first presenting symptom are very rare.

Case presentation: We discuss the case of a 41-year-old Asian woman who presented to our hospital with intermittent palpitation and on evaluation was diagnosed to have systemic sarcoidosis with cardiac involvement. She was started on multiple antiarrhythmic drugs and corticosteroids without any satisfactory response.

Conclusions: Our case report indicates that sarcoidosis can manifest as ventricular tachycardia without any detectable systemic findings. This makes sarcoidosis an important diagnostic consideration in patients with ventricular tachycardia of unknown origin given the high mortality associated with ventricular tachyarrhythmias.

No MeSH data available.


Related in: MedlinePlus