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Stability of cachet phakic intraocular lens position during 6-months follow-up.

Schiano Lomoriello D, Lombardo M, Gualdi L, Iacobelli L, Tranchina L, Ducoli P, Serrao S - Open Ophthalmol J (2013)

Bottom Line: No statistically significant changes of the Cachet pIOL position in the AC were found during follow-up.At the end of follow-up, The mean ECD loss was 0.7 % (from 2794 ± 337 cell/mm(2) to 2776 ± 388 cell/mm(2); P>0.05).A high position stability of the Cachet pIOL in the anterior chamber was shown during a 6-months follow-up.

View Article: PubMed Central - PubMed

Affiliation: Fondazione G.B. Bietti IRCCS, Rome, Italy.

ABSTRACT

Purpose: To evaluate the position stability of a phakic intraocular lens (Cachet pIOL; Alcon, Laboratories, Inc., Fort Worth, TX) in the anterior chamber (AC) during a 6-months follow-up.

Methods: Thirty eyes of 16 subjects underwent a Cachet pIOL implantation for the correction of high myopia from -6.50 to -16.00 D with plano targeted refraction. The position stability of the Cachet pIOL was evaluated using an Anterior Segment-OCT (AS-OCT, Carl Zeiss AG, Oberkochen, Germany) at 1- and 6-months postoperatively. Three measurements have been taken into account: 1) the minimum distance between the anterior surface of the Cachet pIOL optic disk and the central corneal endothelium; 2) the minimum distance between the optic disk's edges of the pIOL and the endothelium; 3) the minimum distance between the posterior surface of the pIOL optic disk and the anterior surface of the crystalline lens. The endothelial cell density (ECD) was also recorded.

Results: No statistically significant changes of the Cachet pIOL position in the AC were found during follow-up. The average changes were ≤0.1 mm between 1- and 6-months postoperatively (P>0.05). At the end of follow-up, The mean ECD loss was 0.7 % (from 2794 ± 337 cell/mm(2) to 2776 ± 388 cell/mm(2); P>0.05).

Conclusion: A high position stability of the Cachet pIOL in the anterior chamber was shown during a 6-months follow-up.

No MeSH data available.


Related in: MedlinePlus

AS-OCT image of the pIOL at 6-months postoperatively.The pIOL design allows the maintenance of a virtually safe distancefrom the anterior chamber structures, including the anterior surfaceof the crystalline lens, the iris, the iridocorneal angle and thecorneal endothelium. The red arrows highlight the minimumdistances, as measured in this study, between (a) the center of thepIOL and the endothelium; (b) the edge of the pIOL and theendothelium; (c) the center of the pIOL center and the crystallinelens.
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Figure 2: AS-OCT image of the pIOL at 6-months postoperatively.The pIOL design allows the maintenance of a virtually safe distancefrom the anterior chamber structures, including the anterior surfaceof the crystalline lens, the iris, the iridocorneal angle and thecorneal endothelium. The red arrows highlight the minimumdistances, as measured in this study, between (a) the center of thepIOL and the endothelium; (b) the edge of the pIOL and theendothelium; (c) the center of the pIOL center and the crystallinelens.

Mentions: The corneal endothelial images were taken at the corneal center using the NonCon-Robo specular microscope (Konan Medical, Inc., Hyogo, Japan). The cell count was performed on two images per eye. At least 50 contiguous cells were marked on each image to estimate the endothelial cell density (ECD). The anterior chamber of each eye was analyzed using an Anterior Segment OCT (AS-OCT, Visante, Zeiss). The stability of the Cachet pIOL position was determined by measuring, at 1- and 6-months postoperatively, the following parameters: 1) the minimum distance between the anterior surface of the Cachet pIOL optic disk and the central corneal endothelium; 2) the minimum distance between the optic disk’s edges of the pIOL and the endothelium; 3) the minimum distance between the posterior surface of the pIOL optic disk and the anterior surface of the crystalline lens (Fig. 2a-c).


Stability of cachet phakic intraocular lens position during 6-months follow-up.

Schiano Lomoriello D, Lombardo M, Gualdi L, Iacobelli L, Tranchina L, Ducoli P, Serrao S - Open Ophthalmol J (2013)

AS-OCT image of the pIOL at 6-months postoperatively.The pIOL design allows the maintenance of a virtually safe distancefrom the anterior chamber structures, including the anterior surfaceof the crystalline lens, the iris, the iridocorneal angle and thecorneal endothelium. The red arrows highlight the minimumdistances, as measured in this study, between (a) the center of thepIOL and the endothelium; (b) the edge of the pIOL and theendothelium; (c) the center of the pIOL center and the crystallinelens.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3722538&req=5

Figure 2: AS-OCT image of the pIOL at 6-months postoperatively.The pIOL design allows the maintenance of a virtually safe distancefrom the anterior chamber structures, including the anterior surfaceof the crystalline lens, the iris, the iridocorneal angle and thecorneal endothelium. The red arrows highlight the minimumdistances, as measured in this study, between (a) the center of thepIOL and the endothelium; (b) the edge of the pIOL and theendothelium; (c) the center of the pIOL center and the crystallinelens.
Mentions: The corneal endothelial images were taken at the corneal center using the NonCon-Robo specular microscope (Konan Medical, Inc., Hyogo, Japan). The cell count was performed on two images per eye. At least 50 contiguous cells were marked on each image to estimate the endothelial cell density (ECD). The anterior chamber of each eye was analyzed using an Anterior Segment OCT (AS-OCT, Visante, Zeiss). The stability of the Cachet pIOL position was determined by measuring, at 1- and 6-months postoperatively, the following parameters: 1) the minimum distance between the anterior surface of the Cachet pIOL optic disk and the central corneal endothelium; 2) the minimum distance between the optic disk’s edges of the pIOL and the endothelium; 3) the minimum distance between the posterior surface of the pIOL optic disk and the anterior surface of the crystalline lens (Fig. 2a-c).

Bottom Line: No statistically significant changes of the Cachet pIOL position in the AC were found during follow-up.At the end of follow-up, The mean ECD loss was 0.7 % (from 2794 ± 337 cell/mm(2) to 2776 ± 388 cell/mm(2); P>0.05).A high position stability of the Cachet pIOL in the anterior chamber was shown during a 6-months follow-up.

View Article: PubMed Central - PubMed

Affiliation: Fondazione G.B. Bietti IRCCS, Rome, Italy.

ABSTRACT

Purpose: To evaluate the position stability of a phakic intraocular lens (Cachet pIOL; Alcon, Laboratories, Inc., Fort Worth, TX) in the anterior chamber (AC) during a 6-months follow-up.

Methods: Thirty eyes of 16 subjects underwent a Cachet pIOL implantation for the correction of high myopia from -6.50 to -16.00 D with plano targeted refraction. The position stability of the Cachet pIOL was evaluated using an Anterior Segment-OCT (AS-OCT, Carl Zeiss AG, Oberkochen, Germany) at 1- and 6-months postoperatively. Three measurements have been taken into account: 1) the minimum distance between the anterior surface of the Cachet pIOL optic disk and the central corneal endothelium; 2) the minimum distance between the optic disk's edges of the pIOL and the endothelium; 3) the minimum distance between the posterior surface of the pIOL optic disk and the anterior surface of the crystalline lens. The endothelial cell density (ECD) was also recorded.

Results: No statistically significant changes of the Cachet pIOL position in the AC were found during follow-up. The average changes were ≤0.1 mm between 1- and 6-months postoperatively (P>0.05). At the end of follow-up, The mean ECD loss was 0.7 % (from 2794 ± 337 cell/mm(2) to 2776 ± 388 cell/mm(2); P>0.05).

Conclusion: A high position stability of the Cachet pIOL in the anterior chamber was shown during a 6-months follow-up.

No MeSH data available.


Related in: MedlinePlus