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Validation of the English version of the UNESP-Botucatu multidimensional composite pain scale for assessing postoperative pain in cats.

Brondani JT, Mama KR, Luna SP, Wright BD, Niyom S, Ambrosio J, Vogel PR, Padovani CR - BMC Vet. Res. (2013)

Bottom Line: Relevant changes in pain scores at clinically distinct time points (e.g., post-surgery, post-analgesic therapy), confirmed the construct validity and responsiveness (Wilcoxon test, p < 0.001).The cut-off point for rescue analgesia was > 7 (range 0-30 points) with 96.5% sensitivity and 99.5% specificity.The cut-off point for rescue analgesia provides an additional tool for guiding analgesic therapy.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, UNESP Univ Estadual Paulista, Botucatu, SP 18618-970, Brazil.

ABSTRACT

Background: A scale validated in one language is not automatically valid in another language or culture. The purpose of this study was to validate the English version of the UNESP-Botucatu multidimensional composite pain scale (MCPS) to assess postoperative pain in cats. The English version was developed using translation, back-translation, and review by individuals with expertise in feline pain management. In sequence, validity and reliability tests were performed.

Results: Of the three domains identified by factor analysis, the internal consistency was excellent for 'pain expression' and 'psychomotor change' (0.86 and 0.87) but not for 'physiological variables' (0.28). Relevant changes in pain scores at clinically distinct time points (e.g., post-surgery, post-analgesic therapy), confirmed the construct validity and responsiveness (Wilcoxon test, p < 0.001). Favorable correlation with the IVAS scores (p < 0.001) and moderate to very good agreement between blinded observers and 'gold standard' evaluations, supported criterion validity. The cut-off point for rescue analgesia was > 7 (range 0-30 points) with 96.5% sensitivity and 99.5% specificity.

Conclusions: The English version of the UNESP-Botucatu-MCPS is a valid, reliable and responsive instrument for assessing acute pain in cats undergoing ovariohysterectomy, when used by anesthesiologists or anesthesia technicians. The cut-off point for rescue analgesia provides an additional tool for guiding analgesic therapy.

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ROC curve and the optimal cut-off point > 7 for rescue analgesia. Receiver Operating Characteristic ROC curve showing the optimal cut-off point > 7 for rescue analgesia (0 – 30 points), with 96.5% of sensitivity, 99.5% of specificity and AUC of 0.996, based on analysis of videos recorded at 4 time points during the perioperative period in cats undergoing ovariohysterectomy.
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Figure 1: ROC curve and the optimal cut-off point > 7 for rescue analgesia. Receiver Operating Characteristic ROC curve showing the optimal cut-off point > 7 for rescue analgesia (0 – 30 points), with 96.5% of sensitivity, 99.5% of specificity and AUC of 0.996, based on analysis of videos recorded at 4 time points during the perioperative period in cats undergoing ovariohysterectomy.

Mentions: From the analysis of the ROC curve, different cut-off points were suggested, highlighting the point represented by the greatest value of the sensitivity and specificity, simultaneously. The optimal cut-off point identified was > 7 (scale range 0 – 30 points), with a sensitivity of 96.5% (95% CI: 92.6 – 98.7%), and specificity of 99.5% (95% CI: 98.3 – 99.9%). The high AUC = 0.996 (95% CI: 0.987 – 0.999; p < 0.001) indicated that the instrument has excellent discriminatory ability (Figures 1 and 2).


Validation of the English version of the UNESP-Botucatu multidimensional composite pain scale for assessing postoperative pain in cats.

Brondani JT, Mama KR, Luna SP, Wright BD, Niyom S, Ambrosio J, Vogel PR, Padovani CR - BMC Vet. Res. (2013)

ROC curve and the optimal cut-off point > 7 for rescue analgesia. Receiver Operating Characteristic ROC curve showing the optimal cut-off point > 7 for rescue analgesia (0 – 30 points), with 96.5% of sensitivity, 99.5% of specificity and AUC of 0.996, based on analysis of videos recorded at 4 time points during the perioperative period in cats undergoing ovariohysterectomy.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3722032&req=5

Figure 1: ROC curve and the optimal cut-off point > 7 for rescue analgesia. Receiver Operating Characteristic ROC curve showing the optimal cut-off point > 7 for rescue analgesia (0 – 30 points), with 96.5% of sensitivity, 99.5% of specificity and AUC of 0.996, based on analysis of videos recorded at 4 time points during the perioperative period in cats undergoing ovariohysterectomy.
Mentions: From the analysis of the ROC curve, different cut-off points were suggested, highlighting the point represented by the greatest value of the sensitivity and specificity, simultaneously. The optimal cut-off point identified was > 7 (scale range 0 – 30 points), with a sensitivity of 96.5% (95% CI: 92.6 – 98.7%), and specificity of 99.5% (95% CI: 98.3 – 99.9%). The high AUC = 0.996 (95% CI: 0.987 – 0.999; p < 0.001) indicated that the instrument has excellent discriminatory ability (Figures 1 and 2).

Bottom Line: Relevant changes in pain scores at clinically distinct time points (e.g., post-surgery, post-analgesic therapy), confirmed the construct validity and responsiveness (Wilcoxon test, p < 0.001).The cut-off point for rescue analgesia was > 7 (range 0-30 points) with 96.5% sensitivity and 99.5% specificity.The cut-off point for rescue analgesia provides an additional tool for guiding analgesic therapy.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, UNESP Univ Estadual Paulista, Botucatu, SP 18618-970, Brazil.

ABSTRACT

Background: A scale validated in one language is not automatically valid in another language or culture. The purpose of this study was to validate the English version of the UNESP-Botucatu multidimensional composite pain scale (MCPS) to assess postoperative pain in cats. The English version was developed using translation, back-translation, and review by individuals with expertise in feline pain management. In sequence, validity and reliability tests were performed.

Results: Of the three domains identified by factor analysis, the internal consistency was excellent for 'pain expression' and 'psychomotor change' (0.86 and 0.87) but not for 'physiological variables' (0.28). Relevant changes in pain scores at clinically distinct time points (e.g., post-surgery, post-analgesic therapy), confirmed the construct validity and responsiveness (Wilcoxon test, p < 0.001). Favorable correlation with the IVAS scores (p < 0.001) and moderate to very good agreement between blinded observers and 'gold standard' evaluations, supported criterion validity. The cut-off point for rescue analgesia was > 7 (range 0-30 points) with 96.5% sensitivity and 99.5% specificity.

Conclusions: The English version of the UNESP-Botucatu-MCPS is a valid, reliable and responsive instrument for assessing acute pain in cats undergoing ovariohysterectomy, when used by anesthesiologists or anesthesia technicians. The cut-off point for rescue analgesia provides an additional tool for guiding analgesic therapy.

Show MeSH
Related in: MedlinePlus