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Doppler echocardiographic indices in aortic coarctation: a comparison of profiles before and after stenting.

Hajsadeghi S, Fereshtehnejad SM, Ojaghi M, Bassiri HA, Keramati MR, Chitsazan M, Gholami S - Cardiovasc J Afr (2012)

Bottom Line: Twenty-three patients, including 16 males and seven females with a mean age of 26.14 ± 10.17 years, were enrolled in this study.Except for the mean velocity and mean pressure gradient of the abdominal aorta, the values of the other indices of the abdominal/descending aorta showed enough change after stenting to indicate significant diagnostic accuracy for detecting aortic coarctation.The velocity-time integral and the pressure half-time were among the indices with the highest accuracy rates for this purpose (all p < 0.001).

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Cardiology, Rasoul-e-Akram Hospital, Tehran University of Medical Sciences, Iran.

ABSTRACT

Background: Diagnosis of aortic coarctation is important as it is a difficult condition to evaluate, especially in adults. A Doppler echocardiographic index could provide a simple tool to evaluate coarctation. This study was performed to compare Doppler echocardiographic profiles before and after stenting and to assess the diagnostic value of a complete list of echocardiographic indices for detecting aortic coarctation.

Methods: This prospective study was conducted on 23 patients with a diagnosis of aortic coarctation based on angiography. Echocardiographic assessment was done twice for all patients before and after stenting. Each time, two-dimensional and Doppler echocardiographic imaging modalities were performed and complete lists of indices were recorded for each case. After comparing the values of indices before and after stenting, diagnostic values of each index were calculated in order to diagnose significant coarctation.

Results: Twenty-three patients, including 16 males and seven females with a mean age of 26.14 ± 10.17 years, were enrolled in this study. Except for the mean velocity and mean pressure gradient of the abdominal aorta, the values of the other indices of the abdominal/descending aorta showed enough change after stenting to indicate significant diagnostic accuracy for detecting aortic coarctation. The velocity-time integral and the pressure half-time were among the indices with the highest accuracy rates for this purpose (all p < 0.001).

Conclusion: Post-stenting echocardiographic profiles could provide a reliable reference value of the normal aortic haemodynamics as a unique identification of each patient and it is presumed that these indices could be used as reliable indicators of response to treatment.

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Related in: MedlinePlus

Cut-off points of 5.98 for pulse delay of descending aorta to differentiate significant coarctation (prestenting condition) from post-stenting condition or without coarctation.
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Figure 3: Cut-off points of 5.98 for pulse delay of descending aorta to differentiate significant coarctation (prestenting condition) from post-stenting condition or without coarctation.

Mentions: A pulse delay of > 5.98 had a sensitivity of 87% and specificity of 95.7% to diagnose significant aortic coarctation (Fig. 3). Moreover, as illustrated in Fig. 4, a pulsatility index of > 1.21 had 87% sensitivity and 91.3% specificity to differentiate significant coarctation (pre-stenting condition) from the post-stenting condition or without coarctation.


Doppler echocardiographic indices in aortic coarctation: a comparison of profiles before and after stenting.

Hajsadeghi S, Fereshtehnejad SM, Ojaghi M, Bassiri HA, Keramati MR, Chitsazan M, Gholami S - Cardiovasc J Afr (2012)

Cut-off points of 5.98 for pulse delay of descending aorta to differentiate significant coarctation (prestenting condition) from post-stenting condition or without coarctation.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3721869&req=5

Figure 3: Cut-off points of 5.98 for pulse delay of descending aorta to differentiate significant coarctation (prestenting condition) from post-stenting condition or without coarctation.
Mentions: A pulse delay of > 5.98 had a sensitivity of 87% and specificity of 95.7% to diagnose significant aortic coarctation (Fig. 3). Moreover, as illustrated in Fig. 4, a pulsatility index of > 1.21 had 87% sensitivity and 91.3% specificity to differentiate significant coarctation (pre-stenting condition) from the post-stenting condition or without coarctation.

Bottom Line: Twenty-three patients, including 16 males and seven females with a mean age of 26.14 ± 10.17 years, were enrolled in this study.Except for the mean velocity and mean pressure gradient of the abdominal aorta, the values of the other indices of the abdominal/descending aorta showed enough change after stenting to indicate significant diagnostic accuracy for detecting aortic coarctation.The velocity-time integral and the pressure half-time were among the indices with the highest accuracy rates for this purpose (all p < 0.001).

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Cardiology, Rasoul-e-Akram Hospital, Tehran University of Medical Sciences, Iran.

ABSTRACT

Background: Diagnosis of aortic coarctation is important as it is a difficult condition to evaluate, especially in adults. A Doppler echocardiographic index could provide a simple tool to evaluate coarctation. This study was performed to compare Doppler echocardiographic profiles before and after stenting and to assess the diagnostic value of a complete list of echocardiographic indices for detecting aortic coarctation.

Methods: This prospective study was conducted on 23 patients with a diagnosis of aortic coarctation based on angiography. Echocardiographic assessment was done twice for all patients before and after stenting. Each time, two-dimensional and Doppler echocardiographic imaging modalities were performed and complete lists of indices were recorded for each case. After comparing the values of indices before and after stenting, diagnostic values of each index were calculated in order to diagnose significant coarctation.

Results: Twenty-three patients, including 16 males and seven females with a mean age of 26.14 ± 10.17 years, were enrolled in this study. Except for the mean velocity and mean pressure gradient of the abdominal aorta, the values of the other indices of the abdominal/descending aorta showed enough change after stenting to indicate significant diagnostic accuracy for detecting aortic coarctation. The velocity-time integral and the pressure half-time were among the indices with the highest accuracy rates for this purpose (all p < 0.001).

Conclusion: Post-stenting echocardiographic profiles could provide a reliable reference value of the normal aortic haemodynamics as a unique identification of each patient and it is presumed that these indices could be used as reliable indicators of response to treatment.

Show MeSH
Related in: MedlinePlus