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The 30-year cardiovascular risk profile of South Africans with diagnosed diabetes, undiagnosed diabetes, pre-diabetes or normoglycaemia: the Bellville, South Africa pilot study.

Matsha TE, Hassan MS, Kidd M, Erasmus RT - Cardiovasc J Afr (2012)

Bottom Line: High CVD risk (> 20%) was evident in normoglycaemic and younger subjects (under 35 years).The high lifetime risk in normoglycaemic and younger subjects may be considered a warning that CVD might take on epidemic proportions in the near future in this country.We recommend the inclusion of education on CVD in school and university curricula.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Bio-Medical Sciences, Faculty of Health and Wellness Science, Cape Peninsula University of Technology, Cape Town, South Africa.

ABSTRACT
The aim of this pilot study was to assess the 30-year risk for cardiovascular disease (CVD) in the South Africa population of mixed-ancestry in individuals with non-diabetic hyperglycaemia, and undiagnosed and self-reported diabetes. Participants were drawn from an urban community of the Bellville South suburb of Cape Town. In total, 583 subjects without a history of CVD were eligible for lifetime CVD risk estimation. Gender-specific prediction for CVD risk was calculated using the 30-year CVD interactive risk calculator. High CVD risk (> 20%) was evident in normoglycaemic and younger subjects (under 35 years). The significant predictors of CVD were sibling history of diabetes, and triglyceride, low-density lipoprotein cholesterol and glycated haemoglobin levels (p < 0.001). The high lifetime risk in normoglycaemic and younger subjects may be considered a warning that CVD might take on epidemic proportions in the near future in this country. We recommend the inclusion of education on CVD in school and university curricula.

No MeSH data available.


Related in: MedlinePlus

CVD risk score for men and women in relation to their age.
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Figure 2: CVD risk score for men and women in relation to their age.

Mentions: The pattern of CVD risk factors used in the 30-year risk calculator is shown in Table 2. Generally, diabetes, hypertension and percentage CVD risk increased with age. On the other hand smoking was more prevalent in the younger age group, 20 to 30 years, while overweight (BMI ≥ 25, < 30 kg/m2) was similar across age groups. While diabetes was highest in the age group 51 to 60 years, undiagnosed diabetes was present in all age groups. The scatter plot in Fig. 2 illustrates the effect of age on increasing CVD risk. Even in those subjects younger than 35 years, some had CVD risk of 20% or more.


The 30-year cardiovascular risk profile of South Africans with diagnosed diabetes, undiagnosed diabetes, pre-diabetes or normoglycaemia: the Bellville, South Africa pilot study.

Matsha TE, Hassan MS, Kidd M, Erasmus RT - Cardiovasc J Afr (2012)

CVD risk score for men and women in relation to their age.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3721868&req=5

Figure 2: CVD risk score for men and women in relation to their age.
Mentions: The pattern of CVD risk factors used in the 30-year risk calculator is shown in Table 2. Generally, diabetes, hypertension and percentage CVD risk increased with age. On the other hand smoking was more prevalent in the younger age group, 20 to 30 years, while overweight (BMI ≥ 25, < 30 kg/m2) was similar across age groups. While diabetes was highest in the age group 51 to 60 years, undiagnosed diabetes was present in all age groups. The scatter plot in Fig. 2 illustrates the effect of age on increasing CVD risk. Even in those subjects younger than 35 years, some had CVD risk of 20% or more.

Bottom Line: High CVD risk (> 20%) was evident in normoglycaemic and younger subjects (under 35 years).The high lifetime risk in normoglycaemic and younger subjects may be considered a warning that CVD might take on epidemic proportions in the near future in this country.We recommend the inclusion of education on CVD in school and university curricula.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Bio-Medical Sciences, Faculty of Health and Wellness Science, Cape Peninsula University of Technology, Cape Town, South Africa.

ABSTRACT
The aim of this pilot study was to assess the 30-year risk for cardiovascular disease (CVD) in the South Africa population of mixed-ancestry in individuals with non-diabetic hyperglycaemia, and undiagnosed and self-reported diabetes. Participants were drawn from an urban community of the Bellville South suburb of Cape Town. In total, 583 subjects without a history of CVD were eligible for lifetime CVD risk estimation. Gender-specific prediction for CVD risk was calculated using the 30-year CVD interactive risk calculator. High CVD risk (> 20%) was evident in normoglycaemic and younger subjects (under 35 years). The significant predictors of CVD were sibling history of diabetes, and triglyceride, low-density lipoprotein cholesterol and glycated haemoglobin levels (p < 0.001). The high lifetime risk in normoglycaemic and younger subjects may be considered a warning that CVD might take on epidemic proportions in the near future in this country. We recommend the inclusion of education on CVD in school and university curricula.

No MeSH data available.


Related in: MedlinePlus