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Reconstructive management of the rare bilateral oral submucos fibrosis using nasolabial flap in comparison with free radial forearm flap--a randomised prospective trial.

Faisal M, Rana M, Shaheen A, Warraich R, Kokemueller H, Eckardt AM, Gellrich NC, Rana M - Orphanet J Rare Dis (2013)

Bottom Line: Surgery remains the main stay in severe cases and aims at release of fibrotic bands and resurfacing the raw areas with different options.Twenty five (25) of these were reconstructed by nasolabial flap and twenty five (25) were reconstructed by radial free forearm flap.At different intervals of their post-operative visits, they were evaluated for the interincisal distance and the difference between the two groups was assessed.RESULTS Average increase in interincisal distance was greater in patients reconstructed with radial free forearm flap compared with patient reconstructed by nasolabial flap i.e. 18.96 mm and 15.16 mm respectively with 'P' value > 0.05.CONCLUSIONS Based on the results of this study, there was no significant difference in mouth opening after reconstruction with radial forearm free flap compared to nasolabial flap [corrected].

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ABSTRACT

Background: Oral sub mucous fibrosis is a rare chronic, progressive, pre malignant collagen disorder of oral mucosa in people of Asian descent characterized by trismus, blanching and stiffness of mucosa, burning sensation in mouth and hypomobility of soft palate and tongue with loss of gustatory sensation. Betel nut chewing is the most common etiological agent. Surgery remains the main stay in severe cases and aims at release of fibrotic bands and resurfacing the raw areas with different options. Reconstruction can be done by using nasolabial flap or radial free forearm flap. The purpose of this study was to compare the mouth opening after the reconstruction with either nasolabial flap or radial free forearm flap.METHODS This study was carried out on fifty (50) patients with oral sub mucous fibrosis. Twenty five (25) of these were reconstructed by nasolabial flap and twenty five (25) were reconstructed by radial free forearm flap. At different intervals of their post-operative visits, they were evaluated for the interincisal distance and the difference between the two groups was assessed.RESULTS Average increase in interincisal distance was greater in patients reconstructed with radial free forearm flap compared with patient reconstructed by nasolabial flap i.e. 18.96 mm and 15.16 mm respectively with 'P' value > 0.05.CONCLUSIONS Based on the results of this study, there was no significant difference in mouth opening after reconstruction with radial forearm free flap compared to nasolabial flap [corrected].

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Frontal intraoral view shows typically precancerous condition with increased prevalence in the Indian subcontinent.
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Figure 2: Frontal intraoral view shows typically precancerous condition with increased prevalence in the Indian subcontinent.

Mentions: A total of 50 adults without sexual discrimination diagnosed clinically and histopathologically for oral submucous fibrosis, were prospectively and observer blind enrolled. The division in two groups occurred randomly. All patients were diagnosed with bilateral oral submucous fibrosis of buccal mucosa (FiguresĀ 1 &2). Exclusion criteria were patients having oral submucous fibrosis extending into pharynx, soft palate, oesophagus or paratubal muscles, malignant change in oral sub mucous fibrosis on biopsy, patients having diabetes mellitus, hypercholesterolemia, arteriosclerosis, blood coagulopathies, collagen vascular disorders and other vascular disorders, previously irradiated patients, intravenous drug abuse.


Reconstructive management of the rare bilateral oral submucos fibrosis using nasolabial flap in comparison with free radial forearm flap--a randomised prospective trial.

Faisal M, Rana M, Shaheen A, Warraich R, Kokemueller H, Eckardt AM, Gellrich NC, Rana M - Orphanet J Rare Dis (2013)

Frontal intraoral view shows typically precancerous condition with increased prevalence in the Indian subcontinent.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3717039&req=5

Figure 2: Frontal intraoral view shows typically precancerous condition with increased prevalence in the Indian subcontinent.
Mentions: A total of 50 adults without sexual discrimination diagnosed clinically and histopathologically for oral submucous fibrosis, were prospectively and observer blind enrolled. The division in two groups occurred randomly. All patients were diagnosed with bilateral oral submucous fibrosis of buccal mucosa (FiguresĀ 1 &2). Exclusion criteria were patients having oral submucous fibrosis extending into pharynx, soft palate, oesophagus or paratubal muscles, malignant change in oral sub mucous fibrosis on biopsy, patients having diabetes mellitus, hypercholesterolemia, arteriosclerosis, blood coagulopathies, collagen vascular disorders and other vascular disorders, previously irradiated patients, intravenous drug abuse.

Bottom Line: Surgery remains the main stay in severe cases and aims at release of fibrotic bands and resurfacing the raw areas with different options.Twenty five (25) of these were reconstructed by nasolabial flap and twenty five (25) were reconstructed by radial free forearm flap.At different intervals of their post-operative visits, they were evaluated for the interincisal distance and the difference between the two groups was assessed.RESULTS Average increase in interincisal distance was greater in patients reconstructed with radial free forearm flap compared with patient reconstructed by nasolabial flap i.e. 18.96 mm and 15.16 mm respectively with 'P' value > 0.05.CONCLUSIONS Based on the results of this study, there was no significant difference in mouth opening after reconstruction with radial forearm free flap compared to nasolabial flap [corrected].

View Article: PubMed Central - HTML - PubMed

ABSTRACT

Background: Oral sub mucous fibrosis is a rare chronic, progressive, pre malignant collagen disorder of oral mucosa in people of Asian descent characterized by trismus, blanching and stiffness of mucosa, burning sensation in mouth and hypomobility of soft palate and tongue with loss of gustatory sensation. Betel nut chewing is the most common etiological agent. Surgery remains the main stay in severe cases and aims at release of fibrotic bands and resurfacing the raw areas with different options. Reconstruction can be done by using nasolabial flap or radial free forearm flap. The purpose of this study was to compare the mouth opening after the reconstruction with either nasolabial flap or radial free forearm flap.METHODS This study was carried out on fifty (50) patients with oral sub mucous fibrosis. Twenty five (25) of these were reconstructed by nasolabial flap and twenty five (25) were reconstructed by radial free forearm flap. At different intervals of their post-operative visits, they were evaluated for the interincisal distance and the difference between the two groups was assessed.RESULTS Average increase in interincisal distance was greater in patients reconstructed with radial free forearm flap compared with patient reconstructed by nasolabial flap i.e. 18.96 mm and 15.16 mm respectively with 'P' value > 0.05.CONCLUSIONS Based on the results of this study, there was no significant difference in mouth opening after reconstruction with radial forearm free flap compared to nasolabial flap [corrected].

Show MeSH
Related in: MedlinePlus