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Evaluation of the association between chronic periodontitis and acute coronary syndrome: A case control study.

Ramesh A, Thomas B, Rao A - J Indian Soc Periodontol (2013)

Bottom Line: Fisher's exact test yielded a p value of 0.4539 with an odds ratio of 0.727(95% confidence interval 0.151 to 3.493).No significant association was found between periodontal disease and acute coronary syndrome.Periodontitis may contribute to cardiovascular disease and stroke in susceptible subjects.

View Article: PubMed Central - PubMed

Affiliation: Department of Periodontics, A B Shetty Memorial Institute of Dental Sciences, Derelakatte, Mangalore, Karnataka, India.

ABSTRACT

Background: The periodontal tissues mount an immune inflammatory response to bacteria and their products and the systemic challenge with these agents also induce a major vascular response. Although many studies have found a correlation between chronic periodontitis and cardiovascular diseases, the role of infection in acute coronary syndrome is disputed. The aim of this study is to investigate whether there is an association between chronic periodontitis and acute coronary syndrome.

Materials and methods: A total of 30 patients, ages ranging from 30 -80. 15 patients from A. B. Shetty Memorial Institute of Dental Sciences and 15 patients admitted to Coronary Care Unit of Justice K. S. Hegde Charitable Hospital Deralakatte Mangalore were included in the study. Variables age more than 40 and gender were also analyzed.

Results: Of the 30 patients analyzed in this study, periodontitis was recognized in 11 patients of the acute coronary syndrome group and 10 patients in the healthy group. Fisher's exact test yielded a p value of 0.4539 with an odds ratio of 0.727(95% confidence interval 0.151 to 3.493).

Conclusion: No significant association was found between periodontal disease and acute coronary syndrome. Periodontitis may contribute to cardiovascular disease and stroke in susceptible subjects. Properly powered longitudinal case control and intervention trials are needed to identify how periodontitis and periodontal interventions may have an impact on cardiovascular diseases.

No MeSH data available.


Related in: MedlinePlus

Measurement of clinical attachment level in a healthy patient with chronic Periodontitis
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Figure 1: Measurement of clinical attachment level in a healthy patient with chronic Periodontitis

Mentions: The severity of chronic periodontitis was determined by clinical attachment loss (CAL) more than 4 mm in more than 30% of sites. CAL was assessed using a Williams's graduated periodontal probe in both arches, examining all the teeth on six surfaces [Figure 1]. The severity of gingivitis was determined by gingival index as given by Loe and Silness, in 1963. Scores 1-3 were recorded with four scoring points on each teeth.


Evaluation of the association between chronic periodontitis and acute coronary syndrome: A case control study.

Ramesh A, Thomas B, Rao A - J Indian Soc Periodontol (2013)

Measurement of clinical attachment level in a healthy patient with chronic Periodontitis
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3713753&req=5

Figure 1: Measurement of clinical attachment level in a healthy patient with chronic Periodontitis
Mentions: The severity of chronic periodontitis was determined by clinical attachment loss (CAL) more than 4 mm in more than 30% of sites. CAL was assessed using a Williams's graduated periodontal probe in both arches, examining all the teeth on six surfaces [Figure 1]. The severity of gingivitis was determined by gingival index as given by Loe and Silness, in 1963. Scores 1-3 were recorded with four scoring points on each teeth.

Bottom Line: Fisher's exact test yielded a p value of 0.4539 with an odds ratio of 0.727(95% confidence interval 0.151 to 3.493).No significant association was found between periodontal disease and acute coronary syndrome.Periodontitis may contribute to cardiovascular disease and stroke in susceptible subjects.

View Article: PubMed Central - PubMed

Affiliation: Department of Periodontics, A B Shetty Memorial Institute of Dental Sciences, Derelakatte, Mangalore, Karnataka, India.

ABSTRACT

Background: The periodontal tissues mount an immune inflammatory response to bacteria and their products and the systemic challenge with these agents also induce a major vascular response. Although many studies have found a correlation between chronic periodontitis and cardiovascular diseases, the role of infection in acute coronary syndrome is disputed. The aim of this study is to investigate whether there is an association between chronic periodontitis and acute coronary syndrome.

Materials and methods: A total of 30 patients, ages ranging from 30 -80. 15 patients from A. B. Shetty Memorial Institute of Dental Sciences and 15 patients admitted to Coronary Care Unit of Justice K. S. Hegde Charitable Hospital Deralakatte Mangalore were included in the study. Variables age more than 40 and gender were also analyzed.

Results: Of the 30 patients analyzed in this study, periodontitis was recognized in 11 patients of the acute coronary syndrome group and 10 patients in the healthy group. Fisher's exact test yielded a p value of 0.4539 with an odds ratio of 0.727(95% confidence interval 0.151 to 3.493).

Conclusion: No significant association was found between periodontal disease and acute coronary syndrome. Periodontitis may contribute to cardiovascular disease and stroke in susceptible subjects. Properly powered longitudinal case control and intervention trials are needed to identify how periodontitis and periodontal interventions may have an impact on cardiovascular diseases.

No MeSH data available.


Related in: MedlinePlus