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Simultaneous spatial and temporal focusing for tissue ablation.

Block E, Greco M, Vitek D, Masihzadeh O, Ammar DA, Kahook MY, Mandava N, Durfee C, Squier J - Biomed Opt Express (2013)

Bottom Line: Simultaneous spatial temporal focusing (SSTF) is used to deliver microjoule femtosecond pulses with low numerical aperture geometries (<0.05 NA) with characteristics that are significantly improved compared to standard focusing paradigms.Nonlinear effects that would normally result in focal plane shifts and focal spot distortion are mitigated when SSTF is employed.As a result, it is shown that SSTF will enable surgical implementations that are presently inhibited.

View Article: PubMed Central - PubMed

Affiliation: Department of Physics, Colorado School of Mines, 1523 Illinois Street, Golden, CO 80401, USA.

ABSTRACT
Simultaneous spatial temporal focusing (SSTF) is used to deliver microjoule femtosecond pulses with low numerical aperture geometries (<0.05 NA) with characteristics that are significantly improved compared to standard focusing paradigms. Nonlinear effects that would normally result in focal plane shifts and focal spot distortion are mitigated when SSTF is employed. As a result, it is shown that SSTF will enable surgical implementations that are presently inhibited.

No MeSH data available.


Related in: MedlinePlus

Single-frame excerpt from a video recording of laser ablation on the surface of a porcine lens mounted in agarose using a standard focusing geometry (Media 1, 685 KB). Two lenses are shown; however, only the lens on the left is being ablated.
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Related In: Results  -  Collection


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g004: Single-frame excerpt from a video recording of laser ablation on the surface of a porcine lens mounted in agarose using a standard focusing geometry (Media 1, 685 KB). Two lenses are shown; however, only the lens on the left is being ablated.

Mentions: First, a standard focusing geometry is used. The beam is focused on the surface of the porcine lens such that it is normally incident with the sample, having a 33 µm spot size (1/e2 diameter) with a 90-degree off-axis parabola, f = 25 mm. The sample is translated laterally at a rate of 0.6 mm/s (~55 pulses per 33 µm spot). Multiple passes were made such that 4 distinct lines (in rows, separated by 200 µm) are cut across the full aperture of the porcine lens. Figure 4Fig. 4


Simultaneous spatial and temporal focusing for tissue ablation.

Block E, Greco M, Vitek D, Masihzadeh O, Ammar DA, Kahook MY, Mandava N, Durfee C, Squier J - Biomed Opt Express (2013)

Single-frame excerpt from a video recording of laser ablation on the surface of a porcine lens mounted in agarose using a standard focusing geometry (Media 1, 685 KB). Two lenses are shown; however, only the lens on the left is being ablated.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3675863&req=5

g004: Single-frame excerpt from a video recording of laser ablation on the surface of a porcine lens mounted in agarose using a standard focusing geometry (Media 1, 685 KB). Two lenses are shown; however, only the lens on the left is being ablated.
Mentions: First, a standard focusing geometry is used. The beam is focused on the surface of the porcine lens such that it is normally incident with the sample, having a 33 µm spot size (1/e2 diameter) with a 90-degree off-axis parabola, f = 25 mm. The sample is translated laterally at a rate of 0.6 mm/s (~55 pulses per 33 µm spot). Multiple passes were made such that 4 distinct lines (in rows, separated by 200 µm) are cut across the full aperture of the porcine lens. Figure 4Fig. 4

Bottom Line: Simultaneous spatial temporal focusing (SSTF) is used to deliver microjoule femtosecond pulses with low numerical aperture geometries (<0.05 NA) with characteristics that are significantly improved compared to standard focusing paradigms.Nonlinear effects that would normally result in focal plane shifts and focal spot distortion are mitigated when SSTF is employed.As a result, it is shown that SSTF will enable surgical implementations that are presently inhibited.

View Article: PubMed Central - PubMed

Affiliation: Department of Physics, Colorado School of Mines, 1523 Illinois Street, Golden, CO 80401, USA.

ABSTRACT
Simultaneous spatial temporal focusing (SSTF) is used to deliver microjoule femtosecond pulses with low numerical aperture geometries (<0.05 NA) with characteristics that are significantly improved compared to standard focusing paradigms. Nonlinear effects that would normally result in focal plane shifts and focal spot distortion are mitigated when SSTF is employed. As a result, it is shown that SSTF will enable surgical implementations that are presently inhibited.

No MeSH data available.


Related in: MedlinePlus