Limits...
Simultaneous spatial and temporal focusing for tissue ablation.

Block E, Greco M, Vitek D, Masihzadeh O, Ammar DA, Kahook MY, Mandava N, Durfee C, Squier J - Biomed Opt Express (2013)

Bottom Line: Simultaneous spatial temporal focusing (SSTF) is used to deliver microjoule femtosecond pulses with low numerical aperture geometries (<0.05 NA) with characteristics that are significantly improved compared to standard focusing paradigms.Nonlinear effects that would normally result in focal plane shifts and focal spot distortion are mitigated when SSTF is employed.As a result, it is shown that SSTF will enable surgical implementations that are presently inhibited.

View Article: PubMed Central - PubMed

Affiliation: Department of Physics, Colorado School of Mines, 1523 Illinois Street, Golden, CO 80401, USA.

ABSTRACT
Simultaneous spatial temporal focusing (SSTF) is used to deliver microjoule femtosecond pulses with low numerical aperture geometries (<0.05 NA) with characteristics that are significantly improved compared to standard focusing paradigms. Nonlinear effects that would normally result in focal plane shifts and focal spot distortion are mitigated when SSTF is employed. As a result, it is shown that SSTF will enable surgical implementations that are presently inhibited.

No MeSH data available.


Related in: MedlinePlus

Image of focus as a function of pulse energy for a standard focal geometry (left) and an SSTF focal geometry (right). The dashed line in the left panel indicates the focal plane of the focusing optic. The beam’s focal position shifts toward this focusing optic as the energy is increased.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC3675863&req=5

g003: Image of focus as a function of pulse energy for a standard focal geometry (left) and an SSTF focal geometry (right). The dashed line in the left panel indicates the focal plane of the focusing optic. The beam’s focal position shifts toward this focusing optic as the energy is increased.

Mentions: We performed an experiment in which energetic pulses were focused in air to explicitly demonstrate the resistance of SSTF pulses to self-focusing and ionization-induced defocusing. A 45-degree off-axis parabola (Edmund Optics #83-970), f = 76.2 mm, was used to focus 40 fs pulses at 800 nm from a 1 kHz chirped pulse amplification system in air to a 8 µm spot size (FWHM) using both SSTF and conventional (non-SSTF) focusing geometries. The plasma breakdown was imaged from above and recorded as a function of increasing pulse energy. Figure 3Fig. 3


Simultaneous spatial and temporal focusing for tissue ablation.

Block E, Greco M, Vitek D, Masihzadeh O, Ammar DA, Kahook MY, Mandava N, Durfee C, Squier J - Biomed Opt Express (2013)

Image of focus as a function of pulse energy for a standard focal geometry (left) and an SSTF focal geometry (right). The dashed line in the left panel indicates the focal plane of the focusing optic. The beam’s focal position shifts toward this focusing optic as the energy is increased.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3675863&req=5

g003: Image of focus as a function of pulse energy for a standard focal geometry (left) and an SSTF focal geometry (right). The dashed line in the left panel indicates the focal plane of the focusing optic. The beam’s focal position shifts toward this focusing optic as the energy is increased.
Mentions: We performed an experiment in which energetic pulses were focused in air to explicitly demonstrate the resistance of SSTF pulses to self-focusing and ionization-induced defocusing. A 45-degree off-axis parabola (Edmund Optics #83-970), f = 76.2 mm, was used to focus 40 fs pulses at 800 nm from a 1 kHz chirped pulse amplification system in air to a 8 µm spot size (FWHM) using both SSTF and conventional (non-SSTF) focusing geometries. The plasma breakdown was imaged from above and recorded as a function of increasing pulse energy. Figure 3Fig. 3

Bottom Line: Simultaneous spatial temporal focusing (SSTF) is used to deliver microjoule femtosecond pulses with low numerical aperture geometries (<0.05 NA) with characteristics that are significantly improved compared to standard focusing paradigms.Nonlinear effects that would normally result in focal plane shifts and focal spot distortion are mitigated when SSTF is employed.As a result, it is shown that SSTF will enable surgical implementations that are presently inhibited.

View Article: PubMed Central - PubMed

Affiliation: Department of Physics, Colorado School of Mines, 1523 Illinois Street, Golden, CO 80401, USA.

ABSTRACT
Simultaneous spatial temporal focusing (SSTF) is used to deliver microjoule femtosecond pulses with low numerical aperture geometries (<0.05 NA) with characteristics that are significantly improved compared to standard focusing paradigms. Nonlinear effects that would normally result in focal plane shifts and focal spot distortion are mitigated when SSTF is employed. As a result, it is shown that SSTF will enable surgical implementations that are presently inhibited.

No MeSH data available.


Related in: MedlinePlus