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Adaptive image guided brachytherapy for cervical cancer: a combined MRI-/CT-planning technique with MRI only at first fraction.

Nesvacil N, Pötter R, Sturdza A, Hegazy N, Federico M, Kirisits C - Radiother Oncol (2012)

Bottom Line: For 20 patients treated with EBRT and HDR BT with tandem/ring applicators two sets of treatment plans were compared.The results show striking similarity to fully MRI-based planning in cases of small tumours and intracavitary applications, both in terms of HR CTV coverage and respecting of OAR dose limits.For larger tumours and complex applications, as well as situations with unfavourable OAR topography, especially for the sigmoid, MRI based adaptive BT planning remains the superior method.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiotherapy, Comprehensive Cancer Center, Medical University of Vienna. nicole.nesvacil@meduniwien.ac.at

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Related in: MedlinePlus

Schematic representation of the dose summation types for the two different treatment planning scenarios: (I) fully MRI-based planning (MRI plan dose), (II) combined MRI/CT-based planning with (IIa) calculation of expected DVH values based on MRI of first and CT of second application (MRI/CT plan – virtual dose) and (IIb) calculation of dose that would be delivered to MRI-based target contours for both applications (MRI/CT plan – real dose).
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f0005: Schematic representation of the dose summation types for the two different treatment planning scenarios: (I) fully MRI-based planning (MRI plan dose), (II) combined MRI/CT-based planning with (IIa) calculation of expected DVH values based on MRI of first and CT of second application (MRI/CT plan – virtual dose) and (IIb) calculation of dose that would be delivered to MRI-based target contours for both applications (MRI/CT plan – real dose).

Mentions: The three types of dose summation are illustrated by a schematic drawing in Fig. 1.


Adaptive image guided brachytherapy for cervical cancer: a combined MRI-/CT-planning technique with MRI only at first fraction.

Nesvacil N, Pötter R, Sturdza A, Hegazy N, Federico M, Kirisits C - Radiother Oncol (2012)

Schematic representation of the dose summation types for the two different treatment planning scenarios: (I) fully MRI-based planning (MRI plan dose), (II) combined MRI/CT-based planning with (IIa) calculation of expected DVH values based on MRI of first and CT of second application (MRI/CT plan – virtual dose) and (IIb) calculation of dose that would be delivered to MRI-based target contours for both applications (MRI/CT plan – real dose).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3675685&req=5

f0005: Schematic representation of the dose summation types for the two different treatment planning scenarios: (I) fully MRI-based planning (MRI plan dose), (II) combined MRI/CT-based planning with (IIa) calculation of expected DVH values based on MRI of first and CT of second application (MRI/CT plan – virtual dose) and (IIb) calculation of dose that would be delivered to MRI-based target contours for both applications (MRI/CT plan – real dose).
Mentions: The three types of dose summation are illustrated by a schematic drawing in Fig. 1.

Bottom Line: For 20 patients treated with EBRT and HDR BT with tandem/ring applicators two sets of treatment plans were compared.The results show striking similarity to fully MRI-based planning in cases of small tumours and intracavitary applications, both in terms of HR CTV coverage and respecting of OAR dose limits.For larger tumours and complex applications, as well as situations with unfavourable OAR topography, especially for the sigmoid, MRI based adaptive BT planning remains the superior method.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiotherapy, Comprehensive Cancer Center, Medical University of Vienna. nicole.nesvacil@meduniwien.ac.at

Show MeSH
Related in: MedlinePlus