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Rhythmic and melodic deviations in musical sequences recruit different cortical areas for mismatch detection.

Lappe C, Steinsträter O, Pantev C - Front Hum Neurosci (2013)

Bottom Line: The MMN to melodic deviations revealed significant right hemispheric neural activation in the superior temporal gyrus (STG), inferior frontal cortex (IFC), and the superior frontal (SFG) and orbitofrontal (OFG) gyri.In contrast, beamformer analysis of the data from the rhythm study revealed bilateral activation within the vicinity of auditory cortices and in the inferior parietal lobule (IPL), an area that has recently been implied in temporal processing.We conclude that different cortical networks are activated in the analysis of the temporal and the melodic content of musical material, and discuss these networks in the context of the dual-pathway model of auditory processing.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Institute for Biomagnetism and Biosignalanalysis, University of Münster Münster, Germany.

ABSTRACT
The mismatch negativity (MMN), an event-related potential (ERP) representing the violation of an acoustic regularity, is considered as a pre-attentive change detection mechanism at the sensory level on the one hand and as a prediction error signal on the other hand, suggesting that bottom-up as well as top-down processes are involved in its generation. Rhythmic and melodic deviations within a musical sequence elicit a MMN in musically trained subjects, indicating that acquired musical expertise leads to better discrimination accuracy of musical material and better predictions about upcoming musical events. Expectation violations to musical material could therefore recruit neural generators that reflect top-down processes that are based on musical knowledge. We describe the neural generators of the musical MMN for rhythmic and melodic material after a short-term sensorimotor-auditory (SA) training. We compare the localization of musical MMN data from two previous MEG studies by applying beamformer analysis. One study focused on the melodic harmonic progression whereas the other study focused on rhythmic progression. The MMN to melodic deviations revealed significant right hemispheric neural activation in the superior temporal gyrus (STG), inferior frontal cortex (IFC), and the superior frontal (SFG) and orbitofrontal (OFG) gyri. IFC and SFG activation was also observed in the left hemisphere. In contrast, beamformer analysis of the data from the rhythm study revealed bilateral activation within the vicinity of auditory cortices and in the inferior parietal lobule (IPL), an area that has recently been implied in temporal processing. We conclude that different cortical networks are activated in the analysis of the temporal and the melodic content of musical material, and discuss these networks in the context of the dual-pathway model of auditory processing.

No MeSH data available.


Related in: MedlinePlus

Axial view of the right hemisphere (overlaid on an individual anatomical MRI) showing significant activations (pseudo-T-values, significance level 5%) of the musically elicited mismatch negativity within a time window of 100–200 ms after the occurrence of a pitch deviation. Panel (A) shows activation in the right STG (MNI coordinates: x = 62, y = −20, z = 16). Panel (B) shows activation in IFC (MNI coordinates: x = 51, y = 12, z = 8), panel (C) shows activation SFG (MNI coordinates: x = 25, y = 55, z = 21), and panels (D) shows activation in OFC (MNI coordinates: x = 35, y = 42, z = −8).
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Figure 3: Axial view of the right hemisphere (overlaid on an individual anatomical MRI) showing significant activations (pseudo-T-values, significance level 5%) of the musically elicited mismatch negativity within a time window of 100–200 ms after the occurrence of a pitch deviation. Panel (A) shows activation in the right STG (MNI coordinates: x = 62, y = −20, z = 16). Panel (B) shows activation in IFC (MNI coordinates: x = 51, y = 12, z = 8), panel (C) shows activation SFG (MNI coordinates: x = 25, y = 55, z = 21), and panels (D) shows activation in OFC (MNI coordinates: x = 35, y = 42, z = −8).

Mentions: The sources of the MMN to melodic deviants were localized in a beamformer analysis (Lappe et al., 2013). This analysis was performed on the post-training data of the SA-group from the melodic MMN study (Lappe et al., 2008) within the time window of 100–200 ms, i.e., at the peak of the MMN response (Figure 1D). The analysis revealed significant neural activation in the superior temporal (STG), the IFC, and the superior frontal (SFG) and the orbitofrontal gyri (OFG) in the right hemisphere (Lappe et al., 2013) (Figure 3). IFC and SFG activation was also observed in the left hemisphere (Figure 4). These results suggested that immediately after the occurrence of a deviant tone a distributed network was activated in right hemispheric auditory cortices, and bilaterally in inferior frontal and prefrontal areas. This gives further evidence that a pitch or harmonic deviation within musical material activates a neural network comprising auditory cortices spreading anterolaterally into inferior and prefrontal areas. The result is in line with the notion that auditory object recognition is supposedly processed in the ventral part of the auditory pathway (Rauschecker and Scott, 2009).


Rhythmic and melodic deviations in musical sequences recruit different cortical areas for mismatch detection.

Lappe C, Steinsträter O, Pantev C - Front Hum Neurosci (2013)

Axial view of the right hemisphere (overlaid on an individual anatomical MRI) showing significant activations (pseudo-T-values, significance level 5%) of the musically elicited mismatch negativity within a time window of 100–200 ms after the occurrence of a pitch deviation. Panel (A) shows activation in the right STG (MNI coordinates: x = 62, y = −20, z = 16). Panel (B) shows activation in IFC (MNI coordinates: x = 51, y = 12, z = 8), panel (C) shows activation SFG (MNI coordinates: x = 25, y = 55, z = 21), and panels (D) shows activation in OFC (MNI coordinates: x = 35, y = 42, z = −8).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3675320&req=5

Figure 3: Axial view of the right hemisphere (overlaid on an individual anatomical MRI) showing significant activations (pseudo-T-values, significance level 5%) of the musically elicited mismatch negativity within a time window of 100–200 ms after the occurrence of a pitch deviation. Panel (A) shows activation in the right STG (MNI coordinates: x = 62, y = −20, z = 16). Panel (B) shows activation in IFC (MNI coordinates: x = 51, y = 12, z = 8), panel (C) shows activation SFG (MNI coordinates: x = 25, y = 55, z = 21), and panels (D) shows activation in OFC (MNI coordinates: x = 35, y = 42, z = −8).
Mentions: The sources of the MMN to melodic deviants were localized in a beamformer analysis (Lappe et al., 2013). This analysis was performed on the post-training data of the SA-group from the melodic MMN study (Lappe et al., 2008) within the time window of 100–200 ms, i.e., at the peak of the MMN response (Figure 1D). The analysis revealed significant neural activation in the superior temporal (STG), the IFC, and the superior frontal (SFG) and the orbitofrontal gyri (OFG) in the right hemisphere (Lappe et al., 2013) (Figure 3). IFC and SFG activation was also observed in the left hemisphere (Figure 4). These results suggested that immediately after the occurrence of a deviant tone a distributed network was activated in right hemispheric auditory cortices, and bilaterally in inferior frontal and prefrontal areas. This gives further evidence that a pitch or harmonic deviation within musical material activates a neural network comprising auditory cortices spreading anterolaterally into inferior and prefrontal areas. The result is in line with the notion that auditory object recognition is supposedly processed in the ventral part of the auditory pathway (Rauschecker and Scott, 2009).

Bottom Line: The MMN to melodic deviations revealed significant right hemispheric neural activation in the superior temporal gyrus (STG), inferior frontal cortex (IFC), and the superior frontal (SFG) and orbitofrontal (OFG) gyri.In contrast, beamformer analysis of the data from the rhythm study revealed bilateral activation within the vicinity of auditory cortices and in the inferior parietal lobule (IPL), an area that has recently been implied in temporal processing.We conclude that different cortical networks are activated in the analysis of the temporal and the melodic content of musical material, and discuss these networks in the context of the dual-pathway model of auditory processing.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Institute for Biomagnetism and Biosignalanalysis, University of Münster Münster, Germany.

ABSTRACT
The mismatch negativity (MMN), an event-related potential (ERP) representing the violation of an acoustic regularity, is considered as a pre-attentive change detection mechanism at the sensory level on the one hand and as a prediction error signal on the other hand, suggesting that bottom-up as well as top-down processes are involved in its generation. Rhythmic and melodic deviations within a musical sequence elicit a MMN in musically trained subjects, indicating that acquired musical expertise leads to better discrimination accuracy of musical material and better predictions about upcoming musical events. Expectation violations to musical material could therefore recruit neural generators that reflect top-down processes that are based on musical knowledge. We describe the neural generators of the musical MMN for rhythmic and melodic material after a short-term sensorimotor-auditory (SA) training. We compare the localization of musical MMN data from two previous MEG studies by applying beamformer analysis. One study focused on the melodic harmonic progression whereas the other study focused on rhythmic progression. The MMN to melodic deviations revealed significant right hemispheric neural activation in the superior temporal gyrus (STG), inferior frontal cortex (IFC), and the superior frontal (SFG) and orbitofrontal (OFG) gyri. IFC and SFG activation was also observed in the left hemisphere. In contrast, beamformer analysis of the data from the rhythm study revealed bilateral activation within the vicinity of auditory cortices and in the inferior parietal lobule (IPL), an area that has recently been implied in temporal processing. We conclude that different cortical networks are activated in the analysis of the temporal and the melodic content of musical material, and discuss these networks in the context of the dual-pathway model of auditory processing.

No MeSH data available.


Related in: MedlinePlus