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Magnetic resonance imaging of pineal region tumours.

Fang AS, Meyers SP - Insights Imaging (2013)

Bottom Line: Pineal lesions include germ cell tumours, neoplasms arising from the pineal parenchyma, as well as other pineal region masses.A variety of cases of pineal lesions are presented.Knowledge of the imaging characteristics and clinical features of varying pineal lesions can assist in narrowing the differential diagnosis for more accurate and rational therapeutic planning. • Pineal parenchymal tumours show an "explosion" of normal pineal calcifications towards the periphery. • Pineoblastomas often have restricted diffusion, with apparent diffusion coefficient (ADC) values lower than germinomas. • Pineal teratomas and pineal lipomas display fat signal characteristics and fat saturation on MRI. • Pineal lesions in patients with known malignancy should raise suspicion of metastatic involvement. • Pineal cysts and arachnoid cysts show MRI signal characteristics similar to cerebrospinal fluid (CSF).

View Article: PubMed Central - PubMed

Affiliation: Department of Imaging Sciences, University of Rochester Medical Center School of Medicine and Dentistry, 601 Elmwood Ave, Box 648, Rochester, NY, 14642, USA, adam_fang@urmc.rochester.edu.

ABSTRACT

Objectives: Pineal lesions can present as a heterogeneous collection of benign and malignant disease conditions. Pineal lesions include germ cell tumours, neoplasms arising from the pineal parenchyma, as well as other pineal region masses.

Methods: A variety of cases of pineal lesions are presented. The important clinical features and typical imaging findings of each pineal lesion are described with emphasis on their morphological appearance and signal intensity characteristics on magnetic resonance imaging (MRI).

Conclusion: Knowledge of the imaging characteristics and clinical features of varying pineal lesions can assist in narrowing the differential diagnosis for more accurate and rational therapeutic planning.

Teaching points: • Pineal parenchymal tumours show an "explosion" of normal pineal calcifications towards the periphery. • Pineoblastomas often have restricted diffusion, with apparent diffusion coefficient (ADC) values lower than germinomas. • Pineal teratomas and pineal lipomas display fat signal characteristics and fat saturation on MRI. • Pineal lesions in patients with known malignancy should raise suspicion of metastatic involvement. • Pineal cysts and arachnoid cysts show MRI signal characteristics similar to cerebrospinal fluid (CSF).

No MeSH data available.


Related in: MedlinePlus

Pineocytoma in a 35-year-old woman. A well-circumscribed low-attenuated lesion arising from the pineal gland producing the characteristic “explosion” of normal pineal calcifications (arrow) towards the periphery
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Fig1: Pineocytoma in a 35-year-old woman. A well-circumscribed low-attenuated lesion arising from the pineal gland producing the characteristic “explosion” of normal pineal calcifications (arrow) towards the periphery

Mentions: Due to their well-differentiated nature, pineocytomas can be indistinguishable from the normal pineal parenchyma. They are well-circumscribed and unencapsulated tumours that arise and expand from the pineal gland, producing the characteristic “explosion” of normal pineal calcifications towards the periphery (Fig. 1) [9]. On magnetic resonance imaging (MRI), pineocytomas usually have low to intermediate signal on T1-weighted images and intermediate to high signal on T2-weighted images (Fig. 2). These lesions typically show prominent contrast enhancement (Fig. 2). Occasionally cystic or partially cystic pineocytomas are seen, which demonstrate internal or nodular wall enhancement on post-contrast imaging [10, 11]. Pineal apoplexy can occur in rare circumstances.Fig. 1


Magnetic resonance imaging of pineal region tumours.

Fang AS, Meyers SP - Insights Imaging (2013)

Pineocytoma in a 35-year-old woman. A well-circumscribed low-attenuated lesion arising from the pineal gland producing the characteristic “explosion” of normal pineal calcifications (arrow) towards the periphery
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3675249&req=5

Fig1: Pineocytoma in a 35-year-old woman. A well-circumscribed low-attenuated lesion arising from the pineal gland producing the characteristic “explosion” of normal pineal calcifications (arrow) towards the periphery
Mentions: Due to their well-differentiated nature, pineocytomas can be indistinguishable from the normal pineal parenchyma. They are well-circumscribed and unencapsulated tumours that arise and expand from the pineal gland, producing the characteristic “explosion” of normal pineal calcifications towards the periphery (Fig. 1) [9]. On magnetic resonance imaging (MRI), pineocytomas usually have low to intermediate signal on T1-weighted images and intermediate to high signal on T2-weighted images (Fig. 2). These lesions typically show prominent contrast enhancement (Fig. 2). Occasionally cystic or partially cystic pineocytomas are seen, which demonstrate internal or nodular wall enhancement on post-contrast imaging [10, 11]. Pineal apoplexy can occur in rare circumstances.Fig. 1

Bottom Line: Pineal lesions include germ cell tumours, neoplasms arising from the pineal parenchyma, as well as other pineal region masses.A variety of cases of pineal lesions are presented.Knowledge of the imaging characteristics and clinical features of varying pineal lesions can assist in narrowing the differential diagnosis for more accurate and rational therapeutic planning. • Pineal parenchymal tumours show an "explosion" of normal pineal calcifications towards the periphery. • Pineoblastomas often have restricted diffusion, with apparent diffusion coefficient (ADC) values lower than germinomas. • Pineal teratomas and pineal lipomas display fat signal characteristics and fat saturation on MRI. • Pineal lesions in patients with known malignancy should raise suspicion of metastatic involvement. • Pineal cysts and arachnoid cysts show MRI signal characteristics similar to cerebrospinal fluid (CSF).

View Article: PubMed Central - PubMed

Affiliation: Department of Imaging Sciences, University of Rochester Medical Center School of Medicine and Dentistry, 601 Elmwood Ave, Box 648, Rochester, NY, 14642, USA, adam_fang@urmc.rochester.edu.

ABSTRACT

Objectives: Pineal lesions can present as a heterogeneous collection of benign and malignant disease conditions. Pineal lesions include germ cell tumours, neoplasms arising from the pineal parenchyma, as well as other pineal region masses.

Methods: A variety of cases of pineal lesions are presented. The important clinical features and typical imaging findings of each pineal lesion are described with emphasis on their morphological appearance and signal intensity characteristics on magnetic resonance imaging (MRI).

Conclusion: Knowledge of the imaging characteristics and clinical features of varying pineal lesions can assist in narrowing the differential diagnosis for more accurate and rational therapeutic planning.

Teaching points: • Pineal parenchymal tumours show an "explosion" of normal pineal calcifications towards the periphery. • Pineoblastomas often have restricted diffusion, with apparent diffusion coefficient (ADC) values lower than germinomas. • Pineal teratomas and pineal lipomas display fat signal characteristics and fat saturation on MRI. • Pineal lesions in patients with known malignancy should raise suspicion of metastatic involvement. • Pineal cysts and arachnoid cysts show MRI signal characteristics similar to cerebrospinal fluid (CSF).

No MeSH data available.


Related in: MedlinePlus