Fructose and lactose intolerance and malabsorption testing: the relationship with symptoms in functional gastrointestinal disorders.
Bottom Line: The effectiveness of a targeted saccharide-reduced diet was assessed after 6-8 weeks.Non-GI symptoms occurred more commonly in patients with intolerances.Methane breath levels were not associated with constipation using several cut-off thresholds.
Affiliation: Gastroenterology Group Practice, Brain-Gut Research Group, Bern, Switzerland. firstname.lastname@example.orgShow MeSH
Related in: MedlinePlus
Mentions: In patients with fructose or lactose malabsorption, as defined by any of the H2 or CH4 thresholds, diarrhoea was more common than constipation (all P < 0.05) (Figure 3). Conversely, patients with diarrhoea and constipation had a similar prevalence of malabsorption demonstrated by isolated elevation of H2 (14.5% and 11.3%) and CH4 (1.2% and 1.2%) concentrations following fructose and lactose ((7.7% and 6.5%) and (1.4% and 1.6%)) respectively. Furthermore, a majority (69%) of IBS-C patients did not have elevated CH4 levels after either sugar.
Affiliation: Gastroenterology Group Practice, Brain-Gut Research Group, Bern, Switzerland. email@example.com