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Health-related quality of life after laparoscopic and open surgery for rectal cancer in a randomized trial.

Andersson J, Angenete E, Gellerstedt M, Angerås U, Jess P, Rosenberg J, Fürst A, Bonjer J, Haglind E - Br J Surg (2013)

Bottom Line: Previous studies comparing laparoscopic and open surgical techniques have reported improved health-related quality of life (HRQL).The HRQL deteriorated to moderate/severe degrees after surgery, gradually returning to preoperative values over time.Changes in EORTC QLQ-C30 and QLQ-CR38, and EQ-5D™ were not significantly different between the groups regarding global health score or any of the dimensions or symptoms at 4 weeks, 6 or 12 months after surgery.

View Article: PubMed Central - PubMed

Affiliation: Scandinavian Surgical Outcomes Research Group (SSORG), Department of Surgery, Sahlgrenska University Hospital/Östra, Gothenburg, Sweden.

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Study flow chart. HRQL, health-related quality of life; EQ-5D™, EuroQol – 5D
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fig01: Study flow chart. HRQL, health-related quality of life; EQ-5D™, EuroQol – 5D

Mentions: The COLOR II trial included 1103 patients between 2004 and 2010. In all, 617 patients were eligible for the HRQL study (Fig. 1). Thirty-three patients were excluded from the COLOR II trial after randomization as they did not conform to the inclusion criteria, and another 199 were primarily eligible but were not included owing to logistical difficulties in retrieving preoperative HRQL data, organizing preoperative radiation, language difficulties, patients' cognitive disabilities or lack of consent. Thus, 385 patients were included in the study (260 laparoscopic and 125 open). The included patients had a lower American Society of Anesthesiologists grade and fewer had undergone preoperative radiation compared with eligible patients who were not included. Basic demographic characteristics and clinical data did not differ between the laparoscopic and open groups (Table1).


Health-related quality of life after laparoscopic and open surgery for rectal cancer in a randomized trial.

Andersson J, Angenete E, Gellerstedt M, Angerås U, Jess P, Rosenberg J, Fürst A, Bonjer J, Haglind E - Br J Surg (2013)

Study flow chart. HRQL, health-related quality of life; EQ-5D™, EuroQol – 5D
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3672685&req=5

fig01: Study flow chart. HRQL, health-related quality of life; EQ-5D™, EuroQol – 5D
Mentions: The COLOR II trial included 1103 patients between 2004 and 2010. In all, 617 patients were eligible for the HRQL study (Fig. 1). Thirty-three patients were excluded from the COLOR II trial after randomization as they did not conform to the inclusion criteria, and another 199 were primarily eligible but were not included owing to logistical difficulties in retrieving preoperative HRQL data, organizing preoperative radiation, language difficulties, patients' cognitive disabilities or lack of consent. Thus, 385 patients were included in the study (260 laparoscopic and 125 open). The included patients had a lower American Society of Anesthesiologists grade and fewer had undergone preoperative radiation compared with eligible patients who were not included. Basic demographic characteristics and clinical data did not differ between the laparoscopic and open groups (Table1).

Bottom Line: Previous studies comparing laparoscopic and open surgical techniques have reported improved health-related quality of life (HRQL).The HRQL deteriorated to moderate/severe degrees after surgery, gradually returning to preoperative values over time.Changes in EORTC QLQ-C30 and QLQ-CR38, and EQ-5D™ were not significantly different between the groups regarding global health score or any of the dimensions or symptoms at 4 weeks, 6 or 12 months after surgery.

View Article: PubMed Central - PubMed

Affiliation: Scandinavian Surgical Outcomes Research Group (SSORG), Department of Surgery, Sahlgrenska University Hospital/Östra, Gothenburg, Sweden.

Show MeSH
Related in: MedlinePlus