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The Leading Concerns of American Women with Nausea and Vomiting of Pregnancy Calling Motherisk NVP Helpline.

Madjunkova S, Maltepe C, Koren G - Obstet Gynecol Int (2013)

Bottom Line: Of these, 86% called for information on management of NVP with/without questions about fetal drug safety, while 14% called solely about drug safety during pregnancy/breastfeeding.American women need more information on the management of NVP and on a variety of its aspects in addition to the safety and effectiveness of antiemetic medications.Their leading concern was the use of doxylamine and vitamin B6 combination for NVP treatment followed by the use of ondansetron.

View Article: PubMed Central - PubMed

Affiliation: The Motherisk Program, Division of Clinical Pharmacology/Toxicology, The Hospital for Sick Children, The University of Toronto, 555 University Avenue, Toronto, ON, Canada M5G 1X8.

ABSTRACT
Background. Nausea and vomiting of pregnancy (NVP) is the most common medical condition of pregnancy, affecting up to 85% of expecting mothers. In the USA, there is no FDA-approved medication for the treatment of NVP. Objective. To identify the primary concerns of American women leading them to contact the Motherisk NVP Helpline and to characterize the severity of their symptoms and therapy offered in order to develop improved and customized counseling for them. Methods. We reviewed the intake forms of the American women who called the NVP Helpline from 2008 to 2012. We extracted their state of residence, demographic data, severity of NVP symptoms, and other available clinical characteristics. Results. A total of 195 forms were reviewed. Of these, 86% called for information on management of NVP with/without questions about fetal drug safety, while 14% called solely about drug safety during pregnancy/breastfeeding. The majority of women were Caucasian, in their thirties, educated, employed, married and in their second pregnancy. Of them 95% were suffering from moderate-to-severe condition with 13% having hyperemesis gravidarum. Conclusion. American women need more information on the management of NVP and on a variety of its aspects in addition to the safety and effectiveness of antiemetic medications. Their leading concern was the use of doxylamine and vitamin B6 combination for NVP treatment followed by the use of ondansetron.

No MeSH data available.


Related in: MedlinePlus

Distribution of PUQE-24 score among women calling from USA.
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Related In: Results  -  Collection


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fig1: Distribution of PUQE-24 score among women calling from USA.

Mentions: Table 3 presents the severity of NVP symptoms among the callers, using the validated PUQE-24 scores [5], showing most callers suffering from moderate-to-severe conditions, probably leading them to seek advice to try to improve their condition. Distribution of PUQE-24 scores among women calling from USA is given in Figure 1.


The Leading Concerns of American Women with Nausea and Vomiting of Pregnancy Calling Motherisk NVP Helpline.

Madjunkova S, Maltepe C, Koren G - Obstet Gynecol Int (2013)

Distribution of PUQE-24 score among women calling from USA.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3649700&req=5

fig1: Distribution of PUQE-24 score among women calling from USA.
Mentions: Table 3 presents the severity of NVP symptoms among the callers, using the validated PUQE-24 scores [5], showing most callers suffering from moderate-to-severe conditions, probably leading them to seek advice to try to improve their condition. Distribution of PUQE-24 scores among women calling from USA is given in Figure 1.

Bottom Line: Of these, 86% called for information on management of NVP with/without questions about fetal drug safety, while 14% called solely about drug safety during pregnancy/breastfeeding.American women need more information on the management of NVP and on a variety of its aspects in addition to the safety and effectiveness of antiemetic medications.Their leading concern was the use of doxylamine and vitamin B6 combination for NVP treatment followed by the use of ondansetron.

View Article: PubMed Central - PubMed

Affiliation: The Motherisk Program, Division of Clinical Pharmacology/Toxicology, The Hospital for Sick Children, The University of Toronto, 555 University Avenue, Toronto, ON, Canada M5G 1X8.

ABSTRACT
Background. Nausea and vomiting of pregnancy (NVP) is the most common medical condition of pregnancy, affecting up to 85% of expecting mothers. In the USA, there is no FDA-approved medication for the treatment of NVP. Objective. To identify the primary concerns of American women leading them to contact the Motherisk NVP Helpline and to characterize the severity of their symptoms and therapy offered in order to develop improved and customized counseling for them. Methods. We reviewed the intake forms of the American women who called the NVP Helpline from 2008 to 2012. We extracted their state of residence, demographic data, severity of NVP symptoms, and other available clinical characteristics. Results. A total of 195 forms were reviewed. Of these, 86% called for information on management of NVP with/without questions about fetal drug safety, while 14% called solely about drug safety during pregnancy/breastfeeding. The majority of women were Caucasian, in their thirties, educated, employed, married and in their second pregnancy. Of them 95% were suffering from moderate-to-severe condition with 13% having hyperemesis gravidarum. Conclusion. American women need more information on the management of NVP and on a variety of its aspects in addition to the safety and effectiveness of antiemetic medications. Their leading concern was the use of doxylamine and vitamin B6 combination for NVP treatment followed by the use of ondansetron.

No MeSH data available.


Related in: MedlinePlus