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Thyroid disease awareness is associated with high rates of identifying subjects with previously undiagnosed thyroid dysfunction.

Canaris GJ, Tape TG, Wigton RS - BMC Public Health (2013)

Bottom Line: In fact, when compared with a previously published case-control study that reported symptoms, the euthyroid health fair participants reported a higher symptom prevalence (range 3.9% to 66.3%, mean 31.5%), than the euthyroid individuals from the case-control study (range 2% to 54%, mean 17.4%).A high proportion of previously undiagnosed thyroid disease was identified at this health fair.However, this was not the case in this health fair screening population.

View Article: PubMed Central - HTML - PubMed

Affiliation: University of Nebraska Medical Center, College of Medicine, Omaha, NE, USA. gcanaris@unmc.edu

ABSTRACT

Background: Conventional screening for hypothyroidism is controversial. Although hypothyroidism is underdiagnosed, many organizations do not recommend screening, citing low disease prevalence in unselected populations. We studied attendees at a thyroid health fair, hypothesizing that certain patient characteristics would enhance the yield of testing.

Methods: We carried out an observational study of participants at a Michigan health fair that focused on thyroid disease. We collected patient-reported symptoms and demographics by questionnaire, and correlated these with the TSH values obtained through the health fair.

Results: 794 of 858 health fair attendees participated. Most were women, and over 40% reported a family history of thyroid disease. We identified 97 (12.2%) participants with previously unknown thyroid dysfunction. No symptom or combination of symptoms discriminated between hypothyroid and euthyroid individuals. Hypothyroid and euthyroid participants in the health fair reported each symptom with a similar prevalence (p > 0.01), a prevalence which was very high. In fact, when compared with a previously published case-control study that reported symptoms, the euthyroid health fair participants reported a higher symptom prevalence (range 3.9% to 66.3%, mean 31.5%), than the euthyroid individuals from the case-control study (range 2% to 54%, mean 17.4%).

Conclusions: A high proportion of previously undiagnosed thyroid disease was identified at this health fair. We initially hypothesized symptoms would distinguish between thyroid function states. However, this was not the case in this health fair screening population. The prevalence of reported symptoms was similar and high in both euthyroid and hypothyroid participants. Because attendees were self-selected, it is possible that this health fair that focused on thyroid disease attracted participants specifically concerned about thyroid health. Despite the lack of symptom discrimination, the much higher prevalence of hypothyroidism in this study (12%) compared with the general population (<2%) suggests that screening may be appropriate and effective in certain circumstances such as thyroid health fairs.

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Distribution of participants according to number of symptoms reported.
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Figure 1: Distribution of participants according to number of symptoms reported.

Mentions: Health fair participants reported a wide range of symptoms, from absolutely no symptoms to 30 symptoms listed on the questionnaire (Figure 1). The median number of symptoms reported by all health fair participants was ten, and mean number of symptoms was eleven.


Thyroid disease awareness is associated with high rates of identifying subjects with previously undiagnosed thyroid dysfunction.

Canaris GJ, Tape TG, Wigton RS - BMC Public Health (2013)

Distribution of participants according to number of symptoms reported.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3643833&req=5

Figure 1: Distribution of participants according to number of symptoms reported.
Mentions: Health fair participants reported a wide range of symptoms, from absolutely no symptoms to 30 symptoms listed on the questionnaire (Figure 1). The median number of symptoms reported by all health fair participants was ten, and mean number of symptoms was eleven.

Bottom Line: In fact, when compared with a previously published case-control study that reported symptoms, the euthyroid health fair participants reported a higher symptom prevalence (range 3.9% to 66.3%, mean 31.5%), than the euthyroid individuals from the case-control study (range 2% to 54%, mean 17.4%).A high proportion of previously undiagnosed thyroid disease was identified at this health fair.However, this was not the case in this health fair screening population.

View Article: PubMed Central - HTML - PubMed

Affiliation: University of Nebraska Medical Center, College of Medicine, Omaha, NE, USA. gcanaris@unmc.edu

ABSTRACT

Background: Conventional screening for hypothyroidism is controversial. Although hypothyroidism is underdiagnosed, many organizations do not recommend screening, citing low disease prevalence in unselected populations. We studied attendees at a thyroid health fair, hypothesizing that certain patient characteristics would enhance the yield of testing.

Methods: We carried out an observational study of participants at a Michigan health fair that focused on thyroid disease. We collected patient-reported symptoms and demographics by questionnaire, and correlated these with the TSH values obtained through the health fair.

Results: 794 of 858 health fair attendees participated. Most were women, and over 40% reported a family history of thyroid disease. We identified 97 (12.2%) participants with previously unknown thyroid dysfunction. No symptom or combination of symptoms discriminated between hypothyroid and euthyroid individuals. Hypothyroid and euthyroid participants in the health fair reported each symptom with a similar prevalence (p > 0.01), a prevalence which was very high. In fact, when compared with a previously published case-control study that reported symptoms, the euthyroid health fair participants reported a higher symptom prevalence (range 3.9% to 66.3%, mean 31.5%), than the euthyroid individuals from the case-control study (range 2% to 54%, mean 17.4%).

Conclusions: A high proportion of previously undiagnosed thyroid disease was identified at this health fair. We initially hypothesized symptoms would distinguish between thyroid function states. However, this was not the case in this health fair screening population. The prevalence of reported symptoms was similar and high in both euthyroid and hypothyroid participants. Because attendees were self-selected, it is possible that this health fair that focused on thyroid disease attracted participants specifically concerned about thyroid health. Despite the lack of symptom discrimination, the much higher prevalence of hypothyroidism in this study (12%) compared with the general population (<2%) suggests that screening may be appropriate and effective in certain circumstances such as thyroid health fairs.

Show MeSH
Related in: MedlinePlus