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Accessory breast cancer occurring concurrently with bilateral primary invasive breast carcinomas: a report of two cases and literature review.

Hao JY, Yang CC, Liu FF, Yang YL, Li S, Li WD, Li YQ, Lang RG, Fan Y, Paulos E, Zhang XM, Fu L - Cancer Biol Med (2012)

Bottom Line: The development of accessory breast tissue, which is found anywhere along the milk line, is attributed to the failure of milk line remnants to regress during embryogenesis.The second case was a 53-year-old Chinese female with bilateral breast cancer (apocrine carcinoma) accompanied by an accessory breast carcinoma (IDC-NOS) in her right axilla that was also incidentally identified.The patient was surgically treated after three doses of cyclophosphamide epirubicin docetaxel (CET) neoadjuvant chemotherapy, followed by adjuvant chemotherapy of the same regimen.

View Article: PubMed Central - PubMed

Affiliation: Department of Breast Cancer Pathology and Research Laboratory, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Breast Cancer Prevention and Therapy, Ministry of Education, Tianjin 300060, China.

ABSTRACT
The development of accessory breast tissue, which is found anywhere along the milk line, is attributed to the failure of milk line remnants to regress during embryogenesis. Primary tumors may arise from any ectopic breast tissue. Accessory breast cancer occurring concurrently with primary invasive breast cancer is extremely rare. Two such cases were reported in this article. One was a 43-year-old Chinese female who exhibited bilateral breast cancer (invasive ductal carcinoma, not otherwise specified, IDC-NOS) and an accessory breast carcinoma (IDC-NOS) incidentally identified in her left axilla. The ectopic breast tissue in her right axilla presented with adenosis. The patient was surgically treated, followed by postoperative docetaxel epirubicin (TE) chemotherapy. The second case was a 53-year-old Chinese female with bilateral breast cancer (apocrine carcinoma) accompanied by an accessory breast carcinoma (IDC-NOS) in her right axilla that was also incidentally identified. The patient was surgically treated after three doses of cyclophosphamide epirubicin docetaxel (CET) neoadjuvant chemotherapy, followed by adjuvant chemotherapy of the same regimen.

No MeSH data available.


Related in: MedlinePlus

Ductal carcinoma in situ was admixed with the IDC-NOS in the right breast (A) (H&E stain, ×100). Ductal carcinoma in situ was adjacent to the IDC-NOS in the left breast (B) (H&E stain, ×40).
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f2: Ductal carcinoma in situ was admixed with the IDC-NOS in the right breast (A) (H&E stain, ×100). Ductal carcinoma in situ was adjacent to the IDC-NOS in the left breast (B) (H&E stain, ×40).

Mentions: Microscopic examination revealed that the tumors in the right (Figure 2A) and left (Figure 2B) breasts were invasive ductal carcinoma, not otherwise specified (IDC-NOS), histologic grade II. Ductal carcinoma in situ was also noted to be admixed with and adjacent to the invasive carcinoma in each breast. The diagnosis was made according to the World Health Organization 2003 criteria[4]. The tumors spread to one of the 12 lymph nodes in the right axilla, whereas the 14 lymph nodes in the left axilla were spared from metastasis. The right axillary soft tissue mass was ectopic breast tissue with adenosis (Figure 3A). The left axillary mass was an IDC-NOS, histologic grade II, adjacent to benign ectopic breast tissue (Figures 3B and C). No lymphoid tissue was identified in the mass lesion. The mass was far from the pectoral breast parenchyma.


Accessory breast cancer occurring concurrently with bilateral primary invasive breast carcinomas: a report of two cases and literature review.

Hao JY, Yang CC, Liu FF, Yang YL, Li S, Li WD, Li YQ, Lang RG, Fan Y, Paulos E, Zhang XM, Fu L - Cancer Biol Med (2012)

Ductal carcinoma in situ was admixed with the IDC-NOS in the right breast (A) (H&E stain, ×100). Ductal carcinoma in situ was adjacent to the IDC-NOS in the left breast (B) (H&E stain, ×40).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3643663&req=5

f2: Ductal carcinoma in situ was admixed with the IDC-NOS in the right breast (A) (H&E stain, ×100). Ductal carcinoma in situ was adjacent to the IDC-NOS in the left breast (B) (H&E stain, ×40).
Mentions: Microscopic examination revealed that the tumors in the right (Figure 2A) and left (Figure 2B) breasts were invasive ductal carcinoma, not otherwise specified (IDC-NOS), histologic grade II. Ductal carcinoma in situ was also noted to be admixed with and adjacent to the invasive carcinoma in each breast. The diagnosis was made according to the World Health Organization 2003 criteria[4]. The tumors spread to one of the 12 lymph nodes in the right axilla, whereas the 14 lymph nodes in the left axilla were spared from metastasis. The right axillary soft tissue mass was ectopic breast tissue with adenosis (Figure 3A). The left axillary mass was an IDC-NOS, histologic grade II, adjacent to benign ectopic breast tissue (Figures 3B and C). No lymphoid tissue was identified in the mass lesion. The mass was far from the pectoral breast parenchyma.

Bottom Line: The development of accessory breast tissue, which is found anywhere along the milk line, is attributed to the failure of milk line remnants to regress during embryogenesis.The second case was a 53-year-old Chinese female with bilateral breast cancer (apocrine carcinoma) accompanied by an accessory breast carcinoma (IDC-NOS) in her right axilla that was also incidentally identified.The patient was surgically treated after three doses of cyclophosphamide epirubicin docetaxel (CET) neoadjuvant chemotherapy, followed by adjuvant chemotherapy of the same regimen.

View Article: PubMed Central - PubMed

Affiliation: Department of Breast Cancer Pathology and Research Laboratory, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Breast Cancer Prevention and Therapy, Ministry of Education, Tianjin 300060, China.

ABSTRACT
The development of accessory breast tissue, which is found anywhere along the milk line, is attributed to the failure of milk line remnants to regress during embryogenesis. Primary tumors may arise from any ectopic breast tissue. Accessory breast cancer occurring concurrently with primary invasive breast cancer is extremely rare. Two such cases were reported in this article. One was a 43-year-old Chinese female who exhibited bilateral breast cancer (invasive ductal carcinoma, not otherwise specified, IDC-NOS) and an accessory breast carcinoma (IDC-NOS) incidentally identified in her left axilla. The ectopic breast tissue in her right axilla presented with adenosis. The patient was surgically treated, followed by postoperative docetaxel epirubicin (TE) chemotherapy. The second case was a 53-year-old Chinese female with bilateral breast cancer (apocrine carcinoma) accompanied by an accessory breast carcinoma (IDC-NOS) in her right axilla that was also incidentally identified. The patient was surgically treated after three doses of cyclophosphamide epirubicin docetaxel (CET) neoadjuvant chemotherapy, followed by adjuvant chemotherapy of the same regimen.

No MeSH data available.


Related in: MedlinePlus