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MRI manifestions correlate with survival of glioblastoma multiforme patients.

Li WB, Tang K, Chen Q, Li S, Qiu XG, Li SW, Jiang T - Cancer Biol Med (2012)

Bottom Line: Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor.Patients without edema surrounding the tumor had longer OS than those with edema.These features can serve as prognostic indicators for GBM patients.

View Article: PubMed Central - PubMed

Affiliation: Cancer Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.

ABSTRACT

Objective: To identify the correlation between magnetic resonance manifestation and survival of patients with glioblastoma multiforme (GBM).

Methods: The magnetic resonance imaging (MRI) images of 30 glioblastoma patients were collected. Imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging were selected to determine their correlation with patient survival. The relationship between imaging and survival time was studied using SPSS 19.0 software. Kaplan-Meier survival analysis and log-rank test were used to compare the survival curves.

Results: Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor. Patients without edema surrounding the tumor had longer OS than those with edema. Patients with tumor of hyperintensity and/or isointensity in T2-weighted imaging had longer OS than those with hyperintensity and/or isointensity and hypointensity.

Conclusions: Some MR imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging are correlated with the survival of patients with GBM. These features can serve as prognostic indicators for GBM patients.

No MeSH data available.


Related in: MedlinePlus

Intensity in T2 weighted imaging and patient survival.
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f5: Intensity in T2 weighted imaging and patient survival.

Mentions: Among the 30 patients undergoing comprehensive treatment, “hyper or iso” images in T2 were found in 16 cases, with a medium survival time of 108.4 weeks, while the other 14 cases were found to be “hyper/iso/hypo” with a medium survival time of 74.3 weeks. The survival curves of these two groups were compared using log-rank test (χ2=4.232, P=0.039). Figure 5 shows a statistically significant difference in the OS of patients between “hyper or iso” and “hyper/iso/hypo.”


MRI manifestions correlate with survival of glioblastoma multiforme patients.

Li WB, Tang K, Chen Q, Li S, Qiu XG, Li SW, Jiang T - Cancer Biol Med (2012)

Intensity in T2 weighted imaging and patient survival.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3643659&req=5

f5: Intensity in T2 weighted imaging and patient survival.
Mentions: Among the 30 patients undergoing comprehensive treatment, “hyper or iso” images in T2 were found in 16 cases, with a medium survival time of 108.4 weeks, while the other 14 cases were found to be “hyper/iso/hypo” with a medium survival time of 74.3 weeks. The survival curves of these two groups were compared using log-rank test (χ2=4.232, P=0.039). Figure 5 shows a statistically significant difference in the OS of patients between “hyper or iso” and “hyper/iso/hypo.”

Bottom Line: Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor.Patients without edema surrounding the tumor had longer OS than those with edema.These features can serve as prognostic indicators for GBM patients.

View Article: PubMed Central - PubMed

Affiliation: Cancer Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.

ABSTRACT

Objective: To identify the correlation between magnetic resonance manifestation and survival of patients with glioblastoma multiforme (GBM).

Methods: The magnetic resonance imaging (MRI) images of 30 glioblastoma patients were collected. Imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging were selected to determine their correlation with patient survival. The relationship between imaging and survival time was studied using SPSS 19.0 software. Kaplan-Meier survival analysis and log-rank test were used to compare the survival curves.

Results: Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor. Patients without edema surrounding the tumor had longer OS than those with edema. Patients with tumor of hyperintensity and/or isointensity in T2-weighted imaging had longer OS than those with hyperintensity and/or isointensity and hypointensity.

Conclusions: Some MR imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging are correlated with the survival of patients with GBM. These features can serve as prognostic indicators for GBM patients.

No MeSH data available.


Related in: MedlinePlus