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MRI manifestions correlate with survival of glioblastoma multiforme patients.

Li WB, Tang K, Chen Q, Li S, Qiu XG, Li SW, Jiang T - Cancer Biol Med (2012)

Bottom Line: Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor.Patients without edema surrounding the tumor had longer OS than those with edema.These features can serve as prognostic indicators for GBM patients.

View Article: PubMed Central - PubMed

Affiliation: Cancer Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.

ABSTRACT

Objective: To identify the correlation between magnetic resonance manifestation and survival of patients with glioblastoma multiforme (GBM).

Methods: The magnetic resonance imaging (MRI) images of 30 glioblastoma patients were collected. Imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging were selected to determine their correlation with patient survival. The relationship between imaging and survival time was studied using SPSS 19.0 software. Kaplan-Meier survival analysis and log-rank test were used to compare the survival curves.

Results: Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor. Patients without edema surrounding the tumor had longer OS than those with edema. Patients with tumor of hyperintensity and/or isointensity in T2-weighted imaging had longer OS than those with hyperintensity and/or isointensity and hypointensity.

Conclusions: Some MR imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging are correlated with the survival of patients with GBM. These features can serve as prognostic indicators for GBM patients.

No MeSH data available.


Related in: MedlinePlus

Edema surrounding the tumor and patient survival.
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f4: Edema surrounding the tumor and patient survival.

Mentions: Among the 30 patients who underwent comprehensive treatment, “no edema” was found in 4 cases that had a medium survival time of 237.2 weeks; the other 26 cases were found to have “edema” and had a medium survival time of 120.9 weeks. The survival curves of these two groups were compared using log-rank test (χ2=6.617, P=0.013). The results also showed a statistically significant difference in the OS between patients with “no edema” and “edema” as shown in Figure 4.


MRI manifestions correlate with survival of glioblastoma multiforme patients.

Li WB, Tang K, Chen Q, Li S, Qiu XG, Li SW, Jiang T - Cancer Biol Med (2012)

Edema surrounding the tumor and patient survival.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3643659&req=5

f4: Edema surrounding the tumor and patient survival.
Mentions: Among the 30 patients who underwent comprehensive treatment, “no edema” was found in 4 cases that had a medium survival time of 237.2 weeks; the other 26 cases were found to have “edema” and had a medium survival time of 120.9 weeks. The survival curves of these two groups were compared using log-rank test (χ2=6.617, P=0.013). The results also showed a statistically significant difference in the OS between patients with “no edema” and “edema” as shown in Figure 4.

Bottom Line: Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor.Patients without edema surrounding the tumor had longer OS than those with edema.These features can serve as prognostic indicators for GBM patients.

View Article: PubMed Central - PubMed

Affiliation: Cancer Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.

ABSTRACT

Objective: To identify the correlation between magnetic resonance manifestation and survival of patients with glioblastoma multiforme (GBM).

Methods: The magnetic resonance imaging (MRI) images of 30 glioblastoma patients were collected. Imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging were selected to determine their correlation with patient survival. The relationship between imaging and survival time was studied using SPSS 19.0 software. Kaplan-Meier survival analysis and log-rank test were used to compare the survival curves.

Results: Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor. Patients without edema surrounding the tumor had longer OS than those with edema. Patients with tumor of hyperintensity and/or isointensity in T2-weighted imaging had longer OS than those with hyperintensity and/or isointensity and hypointensity.

Conclusions: Some MR imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging are correlated with the survival of patients with GBM. These features can serve as prognostic indicators for GBM patients.

No MeSH data available.


Related in: MedlinePlus