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MRI manifestions correlate with survival of glioblastoma multiforme patients.

Li WB, Tang K, Chen Q, Li S, Qiu XG, Li SW, Jiang T - Cancer Biol Med (2012)

Bottom Line: Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor.Patients without edema surrounding the tumor had longer OS than those with edema.These features can serve as prognostic indicators for GBM patients.

View Article: PubMed Central - PubMed

Affiliation: Cancer Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.

ABSTRACT

Objective: To identify the correlation between magnetic resonance manifestation and survival of patients with glioblastoma multiforme (GBM).

Methods: The magnetic resonance imaging (MRI) images of 30 glioblastoma patients were collected. Imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging were selected to determine their correlation with patient survival. The relationship between imaging and survival time was studied using SPSS 19.0 software. Kaplan-Meier survival analysis and log-rank test were used to compare the survival curves.

Results: Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor. Patients without edema surrounding the tumor had longer OS than those with edema. Patients with tumor of hyperintensity and/or isointensity in T2-weighted imaging had longer OS than those with hyperintensity and/or isointensity and hypointensity.

Conclusions: Some MR imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging are correlated with the survival of patients with GBM. These features can serve as prognostic indicators for GBM patients.

No MeSH data available.


Related in: MedlinePlus

Contrasted enhancement ≤5%.
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f1: Contrasted enhancement ≤5%.

Mentions: The images of the tumor with ≤5% and >5% contrasted enhancement areas are shown in Figures 1 and 2, respectively. Of the 30 patients, the 3 with a tumor having ≤5% contrasted enhancement area had a medium survival time of 179.1 weeks; whereas the 27 with a tumor having >5% contrasted enhancement area had a medium survival time of 73.9 weeks. The two survival curves of these two groups were compared using log-rank teat (χ2=5.307, P=0.021). Based on the result, the difference in the OS between the two groups was statistically significant (Figure 3).


MRI manifestions correlate with survival of glioblastoma multiforme patients.

Li WB, Tang K, Chen Q, Li S, Qiu XG, Li SW, Jiang T - Cancer Biol Med (2012)

Contrasted enhancement ≤5%.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3643659&req=5

f1: Contrasted enhancement ≤5%.
Mentions: The images of the tumor with ≤5% and >5% contrasted enhancement areas are shown in Figures 1 and 2, respectively. Of the 30 patients, the 3 with a tumor having ≤5% contrasted enhancement area had a medium survival time of 179.1 weeks; whereas the 27 with a tumor having >5% contrasted enhancement area had a medium survival time of 73.9 weeks. The two survival curves of these two groups were compared using log-rank teat (χ2=5.307, P=0.021). Based on the result, the difference in the OS between the two groups was statistically significant (Figure 3).

Bottom Line: Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor.Patients without edema surrounding the tumor had longer OS than those with edema.These features can serve as prognostic indicators for GBM patients.

View Article: PubMed Central - PubMed

Affiliation: Cancer Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.

ABSTRACT

Objective: To identify the correlation between magnetic resonance manifestation and survival of patients with glioblastoma multiforme (GBM).

Methods: The magnetic resonance imaging (MRI) images of 30 glioblastoma patients were collected. Imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging were selected to determine their correlation with patient survival. The relationship between imaging and survival time was studied using SPSS 19.0 software. Kaplan-Meier survival analysis and log-rank test were used to compare the survival curves.

Results: Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor. Patients without edema surrounding the tumor had longer OS than those with edema. Patients with tumor of hyperintensity and/or isointensity in T2-weighted imaging had longer OS than those with hyperintensity and/or isointensity and hypointensity.

Conclusions: Some MR imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging are correlated with the survival of patients with GBM. These features can serve as prognostic indicators for GBM patients.

No MeSH data available.


Related in: MedlinePlus