Limits...
Role of cytology in fibroadenoma with clinging carcinoma.

Swetha N, Geetha Ch, Prayaga AK - J Cytol (2013)

Bottom Line: Fibroadenoma is the most common benign breast tumor in adolescent girls and young women with a peak incidence in the second and third decades of life.We describe a case of clinging type of ductal carcinoma in situ (DCIS) arising within a fibroadenoma.Clinging carcinoma, a variant of DCIS is an under recognized entity.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, Nizam's Institute of Medical Sciences, Hyderabad, India.

ABSTRACT
Fibroadenoma is the most common benign breast tumor in adolescent girls and young women with a peak incidence in the second and third decades of life. Carcinoma arising within a fibroadenoma is rare and is usually discovered incidentally. We describe a case of clinging type of ductal carcinoma in situ (DCIS) arising within a fibroadenoma. Clinging carcinoma, a variant of DCIS is an under recognized entity. Diagnosis of DCIS is made based on architecture and cytology. This case report highlights the role of fine needle aspiration cytology in the diagnosis of this entity coexisting in a fibroadenoma.

No MeSH data available.


Related in: MedlinePlus

(a) Benign ductal epithelial cell cluster (Pap, ×100); (b) Lesion with bare bipolar nuclei in the background (MGG, ×400); (c) and (d) Clusters of cells with hyperchromatic nuclei and prominent nucleoli (MGG, ×400)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3643372&req=5

Figure 2: (a) Benign ductal epithelial cell cluster (Pap, ×100); (b) Lesion with bare bipolar nuclei in the background (MGG, ×400); (c) and (d) Clusters of cells with hyperchromatic nuclei and prominent nucleoli (MGG, ×400)

Mentions: The smears from the right breast mass showed three dimensional clusters of cells with hyperchromatic nuclei, prominent nucleoli. There were singly scattered pleomorphic cells with mitotic figures. Admixed with these clusters were benign ductal cells with no nuclear pleomorphism along with myoepithelial cells. A few bare nuclei were also seen. Cytologic diagnosis of duct cell carcinoma of bilateral breast lumps with left axillary lymph node metastasis was made [Figure 2].


Role of cytology in fibroadenoma with clinging carcinoma.

Swetha N, Geetha Ch, Prayaga AK - J Cytol (2013)

(a) Benign ductal epithelial cell cluster (Pap, ×100); (b) Lesion with bare bipolar nuclei in the background (MGG, ×400); (c) and (d) Clusters of cells with hyperchromatic nuclei and prominent nucleoli (MGG, ×400)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3643372&req=5

Figure 2: (a) Benign ductal epithelial cell cluster (Pap, ×100); (b) Lesion with bare bipolar nuclei in the background (MGG, ×400); (c) and (d) Clusters of cells with hyperchromatic nuclei and prominent nucleoli (MGG, ×400)
Mentions: The smears from the right breast mass showed three dimensional clusters of cells with hyperchromatic nuclei, prominent nucleoli. There were singly scattered pleomorphic cells with mitotic figures. Admixed with these clusters were benign ductal cells with no nuclear pleomorphism along with myoepithelial cells. A few bare nuclei were also seen. Cytologic diagnosis of duct cell carcinoma of bilateral breast lumps with left axillary lymph node metastasis was made [Figure 2].

Bottom Line: Fibroadenoma is the most common benign breast tumor in adolescent girls and young women with a peak incidence in the second and third decades of life.We describe a case of clinging type of ductal carcinoma in situ (DCIS) arising within a fibroadenoma.Clinging carcinoma, a variant of DCIS is an under recognized entity.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, Nizam's Institute of Medical Sciences, Hyderabad, India.

ABSTRACT
Fibroadenoma is the most common benign breast tumor in adolescent girls and young women with a peak incidence in the second and third decades of life. Carcinoma arising within a fibroadenoma is rare and is usually discovered incidentally. We describe a case of clinging type of ductal carcinoma in situ (DCIS) arising within a fibroadenoma. Clinging carcinoma, a variant of DCIS is an under recognized entity. Diagnosis of DCIS is made based on architecture and cytology. This case report highlights the role of fine needle aspiration cytology in the diagnosis of this entity coexisting in a fibroadenoma.

No MeSH data available.


Related in: MedlinePlus