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Highlights of HRCT imaging in IPF.

Sverzellati N - Respir. Res. (2013)

Bottom Line: Advances in HRCT scanning and interpretation have facilitated improved accuracy for use in diagnosing IPF, eliminating the need for a surgical biopsy in many patients.The role of routine follow-up with HRCT to monitor patients with IPF remains unclear due to lack of sufficient evidence, although, sometimes follow-up HRCT might be necessary to rule out progressive disease in patients with undetermined diagnosis.Advances in the field of HRCT imaging are discussed, along with insights into the clinical utility of this procedure in the diagnosis and management of IPF.

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Affiliation: Scienze Radiologiche, Padiglione Barbieri, Azienda Ospealiero-Universitaria di Parma, V, Gramsci 14, 43100 Parma, Italy.

ABSTRACT
High-resolution computed tomography (HRCT) imaging has a central role in the diagnosis of interstitial lung diseases, particularly in the evaluation of patients with suspected idiopathic pulmonary fibrosis (IPF). In approximately half of cases, HRCT scans are sufficient to allow a confident IPF diagnosis. Advances in HRCT scanning and interpretation have facilitated improved accuracy for use in diagnosing IPF, eliminating the need for a surgical biopsy in many patients. HRCT may also have a role to play in predicting the prognosis of the disease;. The role of routine follow-up with HRCT to monitor patients with IPF remains unclear due to lack of sufficient evidence, although, sometimes follow-up HRCT might be necessary to rule out progressive disease in patients with undetermined diagnosis. Advances in the field of HRCT imaging are discussed, along with insights into the clinical utility of this procedure in the diagnosis and management of IPF.

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Definite UIP pattern. Transverse high-resolution computed tomography (HRCT) image shows subpleural basal honeycombing (more evident in the left lung) with traction bronchiectasis, reticular and ground-glass opacities.
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Figure 1: Definite UIP pattern. Transverse high-resolution computed tomography (HRCT) image shows subpleural basal honeycombing (more evident in the left lung) with traction bronchiectasis, reticular and ground-glass opacities.

Mentions: The characteristic HRCT features of UIP are a reticular pattern with honeycombing, often associated with traction bronchiectasis; ground glass may be present, but is less extensive than reticular abnormality. Such abnormalities are characteristically basal and peripheral, though often patchy (Figure 1) [4].


Highlights of HRCT imaging in IPF.

Sverzellati N - Respir. Res. (2013)

Definite UIP pattern. Transverse high-resolution computed tomography (HRCT) image shows subpleural basal honeycombing (more evident in the left lung) with traction bronchiectasis, reticular and ground-glass opacities.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3643237&req=5

Figure 1: Definite UIP pattern. Transverse high-resolution computed tomography (HRCT) image shows subpleural basal honeycombing (more evident in the left lung) with traction bronchiectasis, reticular and ground-glass opacities.
Mentions: The characteristic HRCT features of UIP are a reticular pattern with honeycombing, often associated with traction bronchiectasis; ground glass may be present, but is less extensive than reticular abnormality. Such abnormalities are characteristically basal and peripheral, though often patchy (Figure 1) [4].

Bottom Line: Advances in HRCT scanning and interpretation have facilitated improved accuracy for use in diagnosing IPF, eliminating the need for a surgical biopsy in many patients.The role of routine follow-up with HRCT to monitor patients with IPF remains unclear due to lack of sufficient evidence, although, sometimes follow-up HRCT might be necessary to rule out progressive disease in patients with undetermined diagnosis.Advances in the field of HRCT imaging are discussed, along with insights into the clinical utility of this procedure in the diagnosis and management of IPF.

View Article: PubMed Central - HTML - PubMed

Affiliation: Scienze Radiologiche, Padiglione Barbieri, Azienda Ospealiero-Universitaria di Parma, V, Gramsci 14, 43100 Parma, Italy.

ABSTRACT
High-resolution computed tomography (HRCT) imaging has a central role in the diagnosis of interstitial lung diseases, particularly in the evaluation of patients with suspected idiopathic pulmonary fibrosis (IPF). In approximately half of cases, HRCT scans are sufficient to allow a confident IPF diagnosis. Advances in HRCT scanning and interpretation have facilitated improved accuracy for use in diagnosing IPF, eliminating the need for a surgical biopsy in many patients. HRCT may also have a role to play in predicting the prognosis of the disease;. The role of routine follow-up with HRCT to monitor patients with IPF remains unclear due to lack of sufficient evidence, although, sometimes follow-up HRCT might be necessary to rule out progressive disease in patients with undetermined diagnosis. Advances in the field of HRCT imaging are discussed, along with insights into the clinical utility of this procedure in the diagnosis and management of IPF.

Show MeSH
Related in: MedlinePlus