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Belimumab: anti-BLyS monoclonal antibody; Benlysta; BmAb; LymphoStat-B.

- Drugs R D (2010)

Bottom Line: Belimumab is a fully human monoclonal antibody for the treatment of autoimmune disorders that is being developed by Human Genome Sciences and GlaxoSmithKline.Marketing authorization submissions are being prepared in the major markets worldwide.This review discusses the development history and scientific profile of belimumab.

View Article: PubMed Central - PubMed

ABSTRACT
Belimumab is a fully human monoclonal antibody for the treatment of autoimmune disorders that is being developed by Human Genome Sciences and GlaxoSmithKline. Two pivotal phase III trials in systemic lupus erythematosus have been concluded with the primary endpoints being met in both studies. A phase II trial in rheumatoid arthritis has also been completed, with positive results. Marketing authorization submissions are being prepared in the major markets worldwide. This review discusses the development history and scientific profile of belimumab.

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Related in: MedlinePlus

History
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Tab2: History


Belimumab: anti-BLyS monoclonal antibody; Benlysta; BmAb; LymphoStat-B.

- Drugs R D (2010)

History
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3585980&req=5

Tab2: History
Bottom Line: Belimumab is a fully human monoclonal antibody for the treatment of autoimmune disorders that is being developed by Human Genome Sciences and GlaxoSmithKline.Marketing authorization submissions are being prepared in the major markets worldwide.This review discusses the development history and scientific profile of belimumab.

View Article: PubMed Central - PubMed

ABSTRACT
Belimumab is a fully human monoclonal antibody for the treatment of autoimmune disorders that is being developed by Human Genome Sciences and GlaxoSmithKline. Two pivotal phase III trials in systemic lupus erythematosus have been concluded with the primary endpoints being met in both studies. A phase II trial in rheumatoid arthritis has also been completed, with positive results. Marketing authorization submissions are being prepared in the major markets worldwide. This review discusses the development history and scientific profile of belimumab.

Show MeSH
Related in: MedlinePlus