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One-year follow-up of femtosecond laser-assisted penetrating keratoplasty.

Tan JC, Heng WJ - Clin Ophthalmol (2013)

Bottom Line: At one-year follow-up, there was an improvement in unaided visual acuity from a mean preoperative logMAR of 1.67 to 0.44, and best spectacle-corrected visual acuity from a mean preoperative logMAR of 1.33 to 0.13.By postoperative month 3, mean manifest refractive and topographic astigmatism was 2.31 ± 1.41 D and 2.59 ± 1.57 D, respectively.The mean reduction in endothelial cell density was 20.7% after one year of follow-up.

View Article: PubMed Central - PubMed

Affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.

ABSTRACT

Background: The purpose of this report is to describe the initial outcomes of femtosecond laser-assisted penetrating keratoplasty.

Methods: This retrospective surgical case series consisted of 10 eyes from 10 patients undergoing penetrating keratoplasty at a tertiary center. Femtosecond laser was used to perform a zig-square incision on the donor cornea with matched dimensions on the recipient cornea. Outcomes measured included: unaided visual acuity and best spectacle-corrected visual acuity preoperatively and at one, 3, 6, and 12 months postoperatively; manifest refractive and topographic astigmatism at 3, 6, and 12 months postoperatively; and endothelial cell density loss, calculated at the end of the one-year follow-up period.

Results: At one-year follow-up, there was an improvement in unaided visual acuity from a mean preoperative logMAR of 1.67 to 0.44, and best spectacle-corrected visual acuity from a mean preoperative logMAR of 1.33 to 0.13. By postoperative month 3, mean manifest refractive and topographic astigmatism was 2.31 ± 1.41 D and 2.59 ± 1.57 D, respectively. The mean reduction in endothelial cell density was 20.7% after one year of follow-up.

Conclusion: Femtosecond laser-assisted penetrating keratoplasty provided a good visual outcome and early visual rehabilitation due to precise graft-host alignment and reduced astigmatism in the early postoperative months.

No MeSH data available.


Related in: MedlinePlus

Photographs and Optovue® anterior segment optical coherence tomographic image from patient 5. (A) Preoperative photograph. (B) Postoperative photograph at week 8. (C) One year after femtosecond laser-assisted penetrating keratoplasty, there was a smooth anterior surface and good wound healing and apposition of the interlocking zig-square configuration.
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f2-opth-7-403: Photographs and Optovue® anterior segment optical coherence tomographic image from patient 5. (A) Preoperative photograph. (B) Postoperative photograph at week 8. (C) One year after femtosecond laser-assisted penetrating keratoplasty, there was a smooth anterior surface and good wound healing and apposition of the interlocking zig-square configuration.

Mentions: The wound profile after FLPK was demonstrated using Optovue OCT (Figure 2). At one-year follow-up, a smooth contour of the anterior corneal surface with good adhesion along the interface of the wound could be seen. The zig-square wound profile had been successfully achieved as planned. This was similarly demonstrated in Figure 3, which showed the OCT wound profile of patient 9 at the month 6 follow-up visit. The smooth edges of the interface cut by femtosecond laser are demonstrated on histological sectioning (Figure 4).


One-year follow-up of femtosecond laser-assisted penetrating keratoplasty.

Tan JC, Heng WJ - Clin Ophthalmol (2013)

Photographs and Optovue® anterior segment optical coherence tomographic image from patient 5. (A) Preoperative photograph. (B) Postoperative photograph at week 8. (C) One year after femtosecond laser-assisted penetrating keratoplasty, there was a smooth anterior surface and good wound healing and apposition of the interlocking zig-square configuration.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3585506&req=5

f2-opth-7-403: Photographs and Optovue® anterior segment optical coherence tomographic image from patient 5. (A) Preoperative photograph. (B) Postoperative photograph at week 8. (C) One year after femtosecond laser-assisted penetrating keratoplasty, there was a smooth anterior surface and good wound healing and apposition of the interlocking zig-square configuration.
Mentions: The wound profile after FLPK was demonstrated using Optovue OCT (Figure 2). At one-year follow-up, a smooth contour of the anterior corneal surface with good adhesion along the interface of the wound could be seen. The zig-square wound profile had been successfully achieved as planned. This was similarly demonstrated in Figure 3, which showed the OCT wound profile of patient 9 at the month 6 follow-up visit. The smooth edges of the interface cut by femtosecond laser are demonstrated on histological sectioning (Figure 4).

Bottom Line: At one-year follow-up, there was an improvement in unaided visual acuity from a mean preoperative logMAR of 1.67 to 0.44, and best spectacle-corrected visual acuity from a mean preoperative logMAR of 1.33 to 0.13.By postoperative month 3, mean manifest refractive and topographic astigmatism was 2.31 ± 1.41 D and 2.59 ± 1.57 D, respectively.The mean reduction in endothelial cell density was 20.7% after one year of follow-up.

View Article: PubMed Central - PubMed

Affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.

ABSTRACT

Background: The purpose of this report is to describe the initial outcomes of femtosecond laser-assisted penetrating keratoplasty.

Methods: This retrospective surgical case series consisted of 10 eyes from 10 patients undergoing penetrating keratoplasty at a tertiary center. Femtosecond laser was used to perform a zig-square incision on the donor cornea with matched dimensions on the recipient cornea. Outcomes measured included: unaided visual acuity and best spectacle-corrected visual acuity preoperatively and at one, 3, 6, and 12 months postoperatively; manifest refractive and topographic astigmatism at 3, 6, and 12 months postoperatively; and endothelial cell density loss, calculated at the end of the one-year follow-up period.

Results: At one-year follow-up, there was an improvement in unaided visual acuity from a mean preoperative logMAR of 1.67 to 0.44, and best spectacle-corrected visual acuity from a mean preoperative logMAR of 1.33 to 0.13. By postoperative month 3, mean manifest refractive and topographic astigmatism was 2.31 ± 1.41 D and 2.59 ± 1.57 D, respectively. The mean reduction in endothelial cell density was 20.7% after one year of follow-up.

Conclusion: Femtosecond laser-assisted penetrating keratoplasty provided a good visual outcome and early visual rehabilitation due to precise graft-host alignment and reduced astigmatism in the early postoperative months.

No MeSH data available.


Related in: MedlinePlus