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One-year follow-up of femtosecond laser-assisted penetrating keratoplasty.

Tan JC, Heng WJ - Clin Ophthalmol (2013)

Bottom Line: At one-year follow-up, there was an improvement in unaided visual acuity from a mean preoperative logMAR of 1.67 to 0.44, and best spectacle-corrected visual acuity from a mean preoperative logMAR of 1.33 to 0.13.By postoperative month 3, mean manifest refractive and topographic astigmatism was 2.31 ± 1.41 D and 2.59 ± 1.57 D, respectively.The mean reduction in endothelial cell density was 20.7% after one year of follow-up.

View Article: PubMed Central - PubMed

Affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.

ABSTRACT

Background: The purpose of this report is to describe the initial outcomes of femtosecond laser-assisted penetrating keratoplasty.

Methods: This retrospective surgical case series consisted of 10 eyes from 10 patients undergoing penetrating keratoplasty at a tertiary center. Femtosecond laser was used to perform a zig-square incision on the donor cornea with matched dimensions on the recipient cornea. Outcomes measured included: unaided visual acuity and best spectacle-corrected visual acuity preoperatively and at one, 3, 6, and 12 months postoperatively; manifest refractive and topographic astigmatism at 3, 6, and 12 months postoperatively; and endothelial cell density loss, calculated at the end of the one-year follow-up period.

Results: At one-year follow-up, there was an improvement in unaided visual acuity from a mean preoperative logMAR of 1.67 to 0.44, and best spectacle-corrected visual acuity from a mean preoperative logMAR of 1.33 to 0.13. By postoperative month 3, mean manifest refractive and topographic astigmatism was 2.31 ± 1.41 D and 2.59 ± 1.57 D, respectively. The mean reduction in endothelial cell density was 20.7% after one year of follow-up.

Conclusion: Femtosecond laser-assisted penetrating keratoplasty provided a good visual outcome and early visual rehabilitation due to precise graft-host alignment and reduced astigmatism in the early postoperative months.

No MeSH data available.


Related in: MedlinePlus

Side profile of zig-square wound created by the femtosecond laser.
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f1-opth-7-403: Side profile of zig-square wound created by the femtosecond laser.

Mentions: An incision was made on the donor cornea using a 60 kHz or 150 kHz femtosecond laser (IntraLase™ FS Laser, Abbott Medical Optics Inc, Abbott Park, IL) with a zig-square shape pattern. For the donor cornea, the posterior side cut was programmed to be penetrating, and to end 30 μm anterior to the lamellar resection plane. The lamellar resection was set at a depth of 300 μm and extended 30 μm outside the posterior side cut. The anterior side cut was angled at 40 degrees to the anterior corneal surface, and similarly had an overlap of 30 μm with the lamellar resection (Figure 1). The anterior diameter ranged from 7.3 mm to 7.5 mm, and the posterior diameter ranged from 7.6 mm to 7.8 mm (Table 1).


One-year follow-up of femtosecond laser-assisted penetrating keratoplasty.

Tan JC, Heng WJ - Clin Ophthalmol (2013)

Side profile of zig-square wound created by the femtosecond laser.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3585506&req=5

f1-opth-7-403: Side profile of zig-square wound created by the femtosecond laser.
Mentions: An incision was made on the donor cornea using a 60 kHz or 150 kHz femtosecond laser (IntraLase™ FS Laser, Abbott Medical Optics Inc, Abbott Park, IL) with a zig-square shape pattern. For the donor cornea, the posterior side cut was programmed to be penetrating, and to end 30 μm anterior to the lamellar resection plane. The lamellar resection was set at a depth of 300 μm and extended 30 μm outside the posterior side cut. The anterior side cut was angled at 40 degrees to the anterior corneal surface, and similarly had an overlap of 30 μm with the lamellar resection (Figure 1). The anterior diameter ranged from 7.3 mm to 7.5 mm, and the posterior diameter ranged from 7.6 mm to 7.8 mm (Table 1).

Bottom Line: At one-year follow-up, there was an improvement in unaided visual acuity from a mean preoperative logMAR of 1.67 to 0.44, and best spectacle-corrected visual acuity from a mean preoperative logMAR of 1.33 to 0.13.By postoperative month 3, mean manifest refractive and topographic astigmatism was 2.31 ± 1.41 D and 2.59 ± 1.57 D, respectively.The mean reduction in endothelial cell density was 20.7% after one year of follow-up.

View Article: PubMed Central - PubMed

Affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.

ABSTRACT

Background: The purpose of this report is to describe the initial outcomes of femtosecond laser-assisted penetrating keratoplasty.

Methods: This retrospective surgical case series consisted of 10 eyes from 10 patients undergoing penetrating keratoplasty at a tertiary center. Femtosecond laser was used to perform a zig-square incision on the donor cornea with matched dimensions on the recipient cornea. Outcomes measured included: unaided visual acuity and best spectacle-corrected visual acuity preoperatively and at one, 3, 6, and 12 months postoperatively; manifest refractive and topographic astigmatism at 3, 6, and 12 months postoperatively; and endothelial cell density loss, calculated at the end of the one-year follow-up period.

Results: At one-year follow-up, there was an improvement in unaided visual acuity from a mean preoperative logMAR of 1.67 to 0.44, and best spectacle-corrected visual acuity from a mean preoperative logMAR of 1.33 to 0.13. By postoperative month 3, mean manifest refractive and topographic astigmatism was 2.31 ± 1.41 D and 2.59 ± 1.57 D, respectively. The mean reduction in endothelial cell density was 20.7% after one year of follow-up.

Conclusion: Femtosecond laser-assisted penetrating keratoplasty provided a good visual outcome and early visual rehabilitation due to precise graft-host alignment and reduced astigmatism in the early postoperative months.

No MeSH data available.


Related in: MedlinePlus